Success Metrics

Clinical Success Rate
89.7%

Based on 165 completed trials

Completion Rate
90%(165/184)
Active Trials
6(3%)
Results Posted
45%(75 trials)
Terminated
19(9%)

Phase Distribution

Ph early_phase_1
4
2%
Ph phase_2
51
23%
Ph phase_1
28
13%
Ph phase_3
37
17%
Ph phase_4
44
20%
Ph not_applicable
48
22%

Phase Distribution

32

Early Stage

51

Mid Stage

81

Late Stage

Phase Distribution212 total trials
Early Phase 1First-in-human
4(1.9%)
Phase 1Safety & dosage
28(13.2%)
Phase 2Efficacy & side effects
51(24.1%)
Phase 3Large-scale testing
37(17.5%)
Phase 4Post-market surveillance
44(20.8%)
N/ANon-phased studies
48(22.6%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

86.4%

165 of 191 finished

Non-Completion Rate

13.6%

26 ended early

Currently Active

6

trials recruiting

Total Trials

218

all time

Status Distribution
Active(8)
Completed(165)
Terminated(26)
Other(19)

Detailed Status

Completed165
Terminated19
unknown19
Withdrawn7
Recruiting5
Not yet recruiting1

Development Timeline

Analytics

Development Status

Total Trials
218
Active
6
Success Rate
89.7%
Most Advanced
Phase 4

Trials by Phase

Early Phase 14 (1.9%)
Phase 128 (13.2%)
Phase 251 (24.1%)
Phase 337 (17.5%)
Phase 444 (20.8%)
N/A48 (22.6%)

Trials by Status

withdrawn73%
not_yet_recruiting10%
terminated199%
active_not_recruiting10%
completed16576%
enrolling_by_invitation10%
recruiting52%
unknown199%

Recent Activity

Clinical Trials (218)

Showing 20 of 218 trialsScroll for more
NCT05872893Phase 3

Continuous Infusion of First-Generation 5-HT3 Receptor Antagonists in Combination With Dexamethasone

Completed
NCT05378113Phase 2

Ondansetron as a Strategy for Reducing Propofol Injection Pain in Pediatrics: a Randomized Controlled Trial

Terminated
NCT03511118

Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants

Recruiting
NCT03593811Early Phase 1

Noninvasive Markers of Functional Nausea in Children

Completed
NCT05692245Phase 4

Dexamethasone vs Ondansetron After Cesarean Delivery

Completed
NCT06861010Phase 3

Evaluating the Safety and Efficacy of Ondansetron in the Prevention of Post Endoscopic Retrograde Cholangiopancreatography Pancreatitis

Recruiting
NCT07381634Phase 2

The Safety and Efficacy of Ondansetron in Reducing Immune Checkpoint Inhibitor-Related Toxicities

Not Yet Recruiting
NCT02858310Phase 1

E7 TCR T Cells for Human Papillomavirus-Associated Cancers

Completed
NCT02106494Phase 3

A Prospective, Multicenter, Study of APF530 (Granisetron) SC for Prevention of CINV in Patients Receiving HEC

Completed
NCT07334223Not Applicable

Comparison of Intravenous Ondansetron and Low Dose Ketamine in Preventing Post Spinal Shivering

Completed
NCT07310563Phase 1

A Trial to Evaluate Interactions Between Antiemetic Medication and AMG 133 in Participants Living With Overweight or Obesity

Completed
NCT05035407Phase 1

T Cell Receptor Gene Therapy Targeting KK-LC-1 for Gastric, Breast, Cervical, Lung and Other KK-LC-1 Positive Epithelial Cancers

Terminated
NCT04150614Phase 4

BMT-08: A Comparative Effectiveness Study of Transdermal Granisetron to Ondansetron

Recruiting
NCT05439772Phase 4

Examining the Effect of Ondansetron on Bowel Prep Success

Completed
NCT03817970Phase 3

Cisplatin Disposition and Kidney Injury

Active Not Recruiting
NCT04169828Not Applicable

The Ondansetron Premedication Trial in Juvenile Idiopathic Arthritis

Completed
NCT00001337Phase 2

Dose-Adjusted EPOCH Chemotherapy and Rituximab (CD20+) in Previously Untreated Aggressive Non-Hodgkin's Lymphoma

Completed
NCT04503668Phase 3

Olanzapine for the Prevention of Chemotherapy Induced Nausea and Vomiting in Gynecologic Oncology Patients

Terminated
NCT06930456Not Applicable

Comparison Between Intravenous Hydrocortisone and Ondansetron in Prevention of Post Spinal Anesthesia Hypotension

Enrolling By Invitation
NCT06898268Not Applicable

Efficacy and Safety of Ondansetron Versus Metaclopromide Treatment in Infants With Gastro Oesophageal Reflux

Completed

Drug Details

Intervention Type
DRUG
Total Trials
218