Success Metrics

Clinical Success Rate
75.0%

Based on 3 completed trials

Completion Rate
75%(3/4)
Active Trials
2(33%)
Results Posted
33%(1 trials)
Terminated
1(17%)

Phase Distribution

Ph phase_4
1
17%
Ph phase_1
1
17%
Ph early_phase_1
3
50%
Ph phase_2
1
17%

Phase Distribution

4

Early Stage

1

Mid Stage

1

Late Stage

Phase Distribution6 total trials
Early Phase 1First-in-human
3(50.0%)
Phase 1Safety & dosage
1(16.7%)
Phase 2Efficacy & side effects
1(16.7%)
Phase 4Post-market surveillance
1(16.7%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

75.0%

3 of 4 finished

Non-Completion Rate

25.0%

1 ended early

Currently Active

2

trials recruiting

Total Trials

6

all time

Status Distribution
Active(2)
Completed(3)
Terminated(1)

Detailed Status

Completed3
Recruiting2
Terminated1

Development Timeline

Analytics

Development Status

Total Trials
6
Active
2
Success Rate
75.0%
Most Advanced
Phase 4

Trials by Phase

Early Phase 13 (50.0%)
Phase 11 (16.7%)
Phase 21 (16.7%)
Phase 41 (16.7%)

Trials by Status

completed350%
recruiting233%
terminated117%

Recent Activity

2 active trials
Showing 5 of 6
recruitingphase_4

Intrathecal Chemotherapy Through Ommaya Reservoir Upon Her-2 Negative Breast Cancer With Leptomeningeal Metastasis

NCT06230055
completedearly_phase_1

Methotrexate and Etoposide Infusions Into the Fourth Ventricle in Children with Recurrent Posterior Fossa Brain Tumors

NCT02905110
terminatedphase_2

Radiation Therapy Followed by Bleomycin in Treating Adult Patients With Newly Diagnosed Supratentorial Glioblastoma Multiforme

NCT00006916
recruitingearly_phase_1

A Study of CAR-T Cells Therapy for Patients With Relapsed and/or Refractory Central Nervous System Hematological Malignancies

NCT04532203
completedphase_1

Methotrexate Infusion Into Fourth Ventricle in Children With Recurrent Malignant Fourth Ventricular Brain Tumors

NCT02458339
View all 6 trials

Clinical Trials (6)

Showing 6 of 6 trials
NCT06230055Phase 4

Intrathecal Chemotherapy Through Ommaya Reservoir Upon Her-2 Negative Breast Cancer With Leptomeningeal Metastasis

Recruiting
NCT02905110Early Phase 1

Methotrexate and Etoposide Infusions Into the Fourth Ventricle in Children with Recurrent Posterior Fossa Brain Tumors

Completed
NCT00006916Phase 2

Radiation Therapy Followed by Bleomycin in Treating Adult Patients With Newly Diagnosed Supratentorial Glioblastoma Multiforme

Terminated
NCT04532203Early Phase 1

A Study of CAR-T Cells Therapy for Patients With Relapsed and/or Refractory Central Nervous System Hematological Malignancies

Recruiting
NCT02458339Phase 1

Methotrexate Infusion Into Fourth Ventricle in Children With Recurrent Malignant Fourth Ventricular Brain Tumors

Completed
NCT01737671Early Phase 1

Methotrexate Infusion Into the Fourth Ventricle in Children With Malignant Fourth Ventricular Brain Tumors: A Pilot Study

Completed

All 6 trials loaded

Drug Details

Intervention Type
PROCEDURE
Total Trials
6