Success Metrics

Active Trials
10(77%)

Phase Distribution

Ph phase_1
3
23%
Ph phase_2
9
69%
Ph phase_4
1
8%

Phase Distribution

3

Early Stage

9

Mid Stage

1

Late Stage

Phase Distribution13 total trials
Phase 1Safety & dosage
3(23.1%)
Phase 2Efficacy & side effects
9(69.2%)
Phase 4Post-market surveillance
1(7.7%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

0.0%

0 of 0 finished

Non-Completion Rate

0.0%

0 ended early

Currently Active

10

trials recruiting

Total Trials

13

all time

Status Distribution
Active(13)

Detailed Status

Recruiting10
Not yet recruiting3

Development Timeline

Analytics

Development Status

Total Trials
13
Active
10
Success Rate
N/A
Most Advanced
Phase 4

Trials by Phase

Phase 13 (23.1%)
Phase 29 (69.2%)
Phase 41 (7.7%)

Trials by Status

recruiting1077%
not_yet_recruiting323%

Recent Activity

Clinical Trials (13)

Showing 13 of 13 trials
NCT05564390Phase 2

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Recruiting
NCT07411586Phase 1

Phase 1/1b Trial Of Olutasidenib And Ziftomenib For NPM1 And IDH1 Co-Mutated Acute Myeloid Leukemia

Not Yet Recruiting
NCT06782542Phase 2

Olutasidenib, Venetoclax, and Azacitidine in IDH1 Mutated Newly Diagnosed Acute Myeloid Leukemia Patients Eligible for Intensive Induction Chemotherapy

Recruiting
NCT07032727Phase 2

Olutasidenib Combined With Co-targeted Therapy in Relapsed or Refractory IDH1-mutated Myeloid Malignancies Harboring Activated Signaling Pathway Mutations

Recruiting
NCT06597734Phase 2

A Phase 2 Study Evaluating Olutasidenib in Combination With Hypomethylating Agents in Patients With IDH1-mutated Higher-risk Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, or Advanced Myeloproliferative Neoplasm

Recruiting
NCT07153497Phase 2

Testing the Use of an IDH1 Inhibitor, Olutasidenib, in Acute Myeloid Leukemia Added to ASTX727 and Venetoclax; in High-Risk MDS Added to ASTX727; and Alone in Low Risk MDS (A MyeloMATCH Treatment Substudy)

Not Yet Recruiting
NCT06445959Phase 1

Phase 1b/2 Study of Decitabine and Venetoclax in Combination With the Targeted Mutant IDH1 Inhibitor Olutasidenib

Recruiting
NCT07486713Phase 4

Olutasidenib DDI Study in Patients With IDH1 Mutation Positive Malignancies

Recruiting
NCT07471841Phase 2

Olutasidenib in Relapsed IDH1 Mutated AML Patients Who Have Previously Received Venetoclax

Not Yet Recruiting
NCT06543381Phase 1

Olutasidenib for the Treatment of Patients With IDH1 Mutated AML, MDS or CMML After Donor Hematopoietic Cell Transplant

Recruiting
NCT07304011Phase 2

Olutasidenib With Azacitidine Followed by Olutasidenib Maintenance for the Treatment of IDH1-mutated Acute Myeloid Leukemia in Patients With Prior Treatment With Venetoclax Plus a Hypomethylating Agent

Recruiting
NCT06668584Phase 2

A Phase II Open-label Study of Olutasidenib Post-transplant Maintenance Therapy for Patients With IDH1-mutated Myeloid Malignancies

Recruiting
NCT06566742Phase 2

A Phase 2 Study Evaluating Olutasidenib in Patients With IDH1-mutated Clonal Cytopenia of Undetermined Significance and Lower-risk Myelodysplastic/Syndromes/Chronic Myelomonocytic Leukemia.

Recruiting

All 13 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
13