Success Metrics

Clinical Success Rate
100.0%

Based on 8 completed trials

Completion Rate
100%(8/8)
Active Trials
12(52%)
Results Posted
100%(8 trials)

Phase Distribution

Ph phase_1
10
43%
Ph phase_2
12
52%
Ph phase_3
1
4%

Phase Distribution

10

Early Stage

12

Mid Stage

1

Late Stage

Phase Distribution23 total trials
Phase 1Safety & dosage
10(43.5%)
Phase 2Efficacy & side effects
12(52.2%)
Phase 3Large-scale testing
1(4.3%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

80.0%

8 of 10 finished

Non-Completion Rate

20.0%

2 ended early

Currently Active

12

trials recruiting

Total Trials

23

all time

Status Distribution
Active(13)
Completed(8)
Terminated(2)

Detailed Status

Active, not recruiting10
Completed8
Recruiting2
Withdrawn2
Not yet recruiting1

Development Timeline

Analytics

Development Status

Total Trials
23
Active
12
Success Rate
100.0%
Most Advanced
Phase 3

Trials by Phase

Phase 110 (43.5%)
Phase 212 (52.2%)
Phase 31 (4.3%)

Trials by Status

active_not_recruiting1043%
not_yet_recruiting14%
recruiting29%
completed835%
withdrawn29%

Recent Activity

Clinical Trials (23)

Showing 20 of 23 trialsScroll for more
NCT07146230Phase 2

The Selective Personalized Radio-Immunotherapy for Locally Advanced Non-Small Cell Lung Cancer Trial 2

Not Yet Recruiting
NCT03742102Phase 1

A Study of Novel Anti-cancer Agents in Patients With Metastatic Triple Negative Breast Cancer

Active Not Recruiting
NCT04940286Phase 2

Gemcitabine, Nab-paclitaxel, Durvalumab, and Oleclumab Before Surgery for the Treatment of in Resectable/Borderline Resectable Primary Pancreatic Cancer

Active Not Recruiting
NCT04668300Phase 2

Oleclumab and Durvalumab for the Treatment of Recurrent, Refractory, or Metastatic Sarcoma

Active Not Recruiting
NCT06606847Phase 2

A Study to Investigate the Effects of Durvalumab With Oleclumab Following Chemoradiation in Participants With Locally Advanced Unresectable Non-Small Cell Lung Cancer (LADOGA)

Active Not Recruiting
NCT03381274Phase 1

Oleclumab (MEDI9447) Epidermal Growth Factor Receptor Mutant (EGFRm) Non-small Cell Lung Cancer (NSCLC) Novel Combination Study

Active Not Recruiting
NCT05061550Phase 2

Neoadjuvant and Adjuvant Treatment in Resectable Non-small Cell Lung Cancer

Recruiting
NCT04068610Phase 1

COLUMBIA-1: Novel Oncology Therapies in Combination With Chemotherapy and Bevacizumab as First- Line Therapy in MSS-CRC

Active Not Recruiting
NCT03819465Phase 1

A Study of Novel Anti-cancer Agents in Patients With Previously Untreated NSCLC

Active Not Recruiting
NCT05221840Phase 3

A Global Study to Assess the Effects of Durvalumab With Oleclumab or Durvalumab With Monalizumab Following Concurrent Chemoradiation in Patients With Stage III Unresectable Non-Small Cell Lung Cancer

Active Not Recruiting
NCT03334617Phase 2

Phase II Umbrella Study of Novel Anti-cancer Agents in Participants With NSCLC Who Progressed on an Anti-PD-1/PD-L1 Containing Therapy

Active Not Recruiting
NCT03801902Phase 1

Testing the Safety of Adding Either Monalizumab (IPH2201) or Oleclumab (MEDI9447) to Durvalumab (MEDI4736) Plus Standard Radiation Therapy for Locally Advanced Non-small Cell Lung Cancer (NSCLC), ARCHON-1 Trial

Completed
NCT03875573Phase 2

Neo-adjuvant Chemotherapy Combined With Stereotactic Body Radiotherapy to the Primary Tumour +/- Durvalumab, +/- Oleclumab in Luminal B Breast Cancer:

Active Not Recruiting
NCT04089553Phase 2

An Open-label, Phase II Study of AZD4635 in Patients With Prostate Cancer

Completed
NCT06060405Phase 2

Durvalumab and Oleclumab in Resectable PDAC

Recruiting
NCT03611556Phase 1

MEDI9447(Oleclumab) Pancreatic Chemotherapy Combination Study.

Completed
NCT02503774Phase 1

MEDI9447 Alone and in Combination With MEDI4736 in Adult Participants With Select Advanced Solid Tumors.

Completed
NCT02740985Phase 1

A Phase 1 Clinical Study of AZD4635 in Patients With Advanced Solid Malignancies

Completed
NCT03773666Phase 1

A Feasibility Study of Durvalumab +/- Oleclumab as Neoadjuvant Therapy for Muscle-invasive Bladder Cancer (BLASST-2)

Completed
NCT04261075Phase 1

IPH5201 as Monotherapy or in Combination With Durvalumab +/- Oleclumab in Subjects With Advanced Solid Tumors.

Completed

Drug Details

Intervention Type
DRUG
Total Trials
23