Success Metrics

Clinical Success Rate
79.6%

Based on 78 completed trials

Completion Rate
80%(78/98)
Active Trials
17(14%)
Results Posted
85%(66 trials)
Terminated
20(17%)

Phase Distribution

Ph phase_3
21
18%
Ph early_phase_1
1
1%
Ph phase_2
57
48%
Ph phase_4
7
6%
Ph phase_1
13
11%

Phase Distribution

14

Early Stage

57

Mid Stage

28

Late Stage

Phase Distribution99 total trials
Early Phase 1First-in-human
1(1.0%)
Phase 1Safety & dosage
13(13.1%)
Phase 2Efficacy & side effects
57(57.6%)
Phase 3Large-scale testing
21(21.2%)
Phase 4Post-market surveillance
7(7.1%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

78.8%

78 of 99 finished

Non-Completion Rate

21.2%

21 ended early

Currently Active

17

trials recruiting

Total Trials

120

all time

Status Distribution
Active(19)
Completed(78)
Terminated(21)
Other(2)

Detailed Status

Completed78
Terminated20
Recruiting10
Active, not recruiting7
unknown2
Enrolling by invitation1

Development Timeline

Analytics

Development Status

Total Trials
120
Active
17
Success Rate
79.6%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (1.0%)
Phase 113 (13.1%)
Phase 257 (57.6%)
Phase 321 (21.2%)
Phase 47 (7.1%)

Trials by Status

active_not_recruiting76%
enrolling_by_invitation11%
terminated2017%
unknown22%
completed7865%
recruiting108%
withdrawn11%
not_yet_recruiting11%

Recent Activity

Clinical Trials (120)

Showing 20 of 120 trialsScroll for more
NCT05171972

Reduced Oligodendrocyte-specific Cytotoxicity and Ofatumumab Treatment

Completed
NCT03650114Phase 3

Long-term Safety, Tolerability and Effectiveness Study of Ofatumumab in Patients With Relapsing MS

Active Not Recruiting
NCT05344469

A NIS Evaluating Various Injectable and Oral Treatments in Patients With Relapsing Multiple Sclerosis

Recruiting
NCT04926818Phase 3

Efficacy and Safety of Ofatumumab and Siponimod Compared to Fingolimod in Pediatric Patients With Multiple Sclerosis

Active Not Recruiting
NCT06157086

Assessment of the Quality of Life of Multiple Sclerosis Patients Treated With Ofatumumab in Real-life in France

Active Not Recruiting
NCT07546110Early Phase 1

An Open-Label, Single-Arm Clinical Study to Evaluate the Safety and Preliminary Efficacy of CD20 Monoclonal Antibody Combined With NK042 Cell Injection in the Treatment of Multiple Sclerosis (MS).

Not Yet Recruiting
NCT05285904

Kesimpta® (Ofatumumab) in Swiss Multiple Sclerosis Patients - an Observational Study

Completed
NCT06345157

ITAKOS - Italian Observation, Multicenter, Prospective Study of Ofatumumab in RRMS Patients

Active Not Recruiting
NCT04353492Phase 3

An Open-label Study Evaluating Ofatumumab Treatment Effectiveness and PROs in Subjects With RMS Transitioning From Fumarate-based RMS Approved Therapies or Fingolimod to Ofatumumab

Completed
NCT06551519

A Non-interventional Study Evaluating Clinical Utility and Implications on Improved Patient Management of Serum Neurofilament as a Prognostic Marker for Disease Activity in Patients With Relapsing Multiple Sclerosis

Recruiting
NCT05090371Phase 4

A Multicenter Study of Continued Current Therapy vs Transition to Ofatumumab After Neurofilament (NfL) Elevation

Active Not Recruiting
NCT02135133Phase 2

A Study of Idelalisib (GS1101, CAL101) + Ofatumumab in Previously Untreated CLL/SLL

Completed
NCT05090033

Characterizing the Use of Ofatumumab in a Real World Setting

Completed
NCT04788615Phase 3

Open Label Randomized Multicenter to Assess Efficacy & Tolerability of Ofatumumab 20mg vs. First Line DMT in RMS

Completed
NCT05084638Phase 4

Study to Assess the Effect of Ofatumumab in Treatment Naïve, Very Early RRMS Patients Benchmarked Against Healthy Controls.

Completed
NCT03136146Phase 2

Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma, Burkitt Lymphoma/Leukemia, or Double-Hit Lymphoma/Leukemia

Recruiting
NCT05504694Phase 1

Ofatumumab in AQP4-IgG Seropositive NMOSD

Recruiting
NCT04510220Phase 3

9-month Study to Assess the Efficacy of Ofatumumab on Microglia in Patients With Relapsing Forms of Multiple Sclerosis

Completed
NCT07353216

Exploring the Efficacy and Safety of Ofatumumab in Patients With Relapsing Multiple Sclerosis (RMS) and Its Impact on Serum Neurofilament Light Chain (sNfL) Levels

Recruiting
NCT05199571Phase 4

Study of Efficacy and Safety of Ofatumumab in Relapsing Multiple Sclerosis (RMS) Patients in China

Completed

Drug Details

Intervention Type
DRUG
Total Trials
120