Success Metrics

Clinical Success Rate
72.6%

Based on 82 completed trials

Completion Rate
73%(82/113)
Active Trials
114(43%)
Results Posted
91%(75 trials)
Terminated
31(12%)

Phase Distribution

Ph phase_2
122
46%
Ph phase_3
40
15%
Ph phase_1
92
35%
Ph not_applicable
2
1%
Ph phase_4
1
0%

Phase Distribution

92

Early Stage

122

Mid Stage

41

Late Stage

Phase Distribution257 total trials
Phase 1Safety & dosage
92(35.8%)
Phase 2Efficacy & side effects
122(47.5%)
Phase 3Large-scale testing
40(15.6%)
Phase 4Post-market surveillance
1(0.4%)
N/ANon-phased studies
2(0.8%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

68.3%

82 of 120 finished

Non-Completion Rate

31.7%

38 ended early

Currently Active

114

trials recruiting

Total Trials

265

all time

Status Distribution
Active(138)
Completed(82)
Terminated(38)
Other(7)

Detailed Status

Completed82
Active, not recruiting58
Recruiting56
Terminated31
Not yet recruiting24
Withdrawn7

Development Timeline

Analytics

Development Status

Total Trials
265
Active
114
Success Rate
72.6%
Most Advanced
Phase 4

Trials by Phase

Phase 192 (35.8%)
Phase 2122 (47.5%)
Phase 340 (15.6%)
Phase 41 (0.4%)
N/A2 (0.8%)

Trials by Status

withdrawn73%
active_not_recruiting5822%
suspended21%
not_yet_recruiting249%
terminated3112%
unknown52%
completed8231%
recruiting5621%

Recent Activity

Clinical Trials (265)

Showing 20 of 265 trialsScroll for more
NCT04408638Phase 3

A Phase III Study Evaluating Glofitamab in Combination With Gemcitabine + Oxaliplatin vs Rituximab in Combination With Gemcitabine + Oxaliplatin in Participants With Relapsed/Refractory Diffuse Large B-Cell Lymphoma

Active Not Recruiting
NCT03533283Phase 1

An Open-Label Phase lB/II Study of Glofitamab and Atezolizumab or Polatuzumab Vedotin in Adult Patients With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma

Active Not Recruiting
NCT03872180Phase 2

Bendamustine, Obinutuzumab, and Venetoclax in Patients With Untreated Mantle Cell Lymphoma

Active Not Recruiting
NCT03701282Phase 3

Assessing the Ability of Combination Treatment With Venetoclax to Permit Time Limited Therapy in Chronic Lymphocytic Leukemia

Active Not Recruiting
NCT04629248Phase 3

A Study Evaluating the Efficacy and Safety of Obinutuzumab in Participants With Primary Membranous Nephropathy

Active Not Recruiting
NCT03516617Phase 2

Acalabrutinib With or Without Obinutuzumab in Treating Patients With Early-Stage Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Recruiting
NCT06649812Phase 2

Testing the Effectiveness of a Combination Targeted Therapy (ViPOR) for Patients With Relapsed and/or Refractory Aggressive B-cell Lymphoma

Recruiting
NCT06252675Phase 2

Glofitamab With Pirtobrutinib for Relapsed or Refractory Mantle Cell Lymphoma

Recruiting
NCT04560322Phase 2

Venetoclax-Obinutuzumab +/- Acalabrutinib in R/R CLL

Active Not Recruiting
NCT04269902Phase 3

Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

Recruiting
NCT01414855Phase 2

A Study of Obinutuzumab [RO5072759 (GA101)] in Combination With CHOP Chemotherapy in Patients With Previously Untreated Advanced Diffuse Large B-Cell Lymphoma (GATHER)

Completed
NCT07847957Phase 1

Roginolisib Plus Obinutuzumab + Venetoclax in R/R CLL

Not Yet Recruiting
NCT06943872Phase 3

A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)

Recruiting
NCT03462719Phase 3

A Study of the Combination of Ibrutinib Plus Venetoclax Versus Chlorambucil Plus Obinutuzumab for the First-line Treatment of Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

Active Not Recruiting
NCT03223610Phase 1

Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid (ViPOR) in Relapsed/Refractory B-cell Lymphoma

Recruiting
NCT06073821Phase 3

Study of Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Obinutuzumab in Participants With Chronic Lymphocytic Leukemia (CLL)

Active Not Recruiting
NCT05100862Phase 3

A Study of Zanubrutinib Plus Anti-CD20 Versus Lenalidomide Plus Rituximab in Participants With Relapsed/Refractory Follicular or Marginal Zone Lymphoma

Active Not Recruiting
NCT05783596Phase 2

Glofit and Obin in Follicular Lymphoma and Marginal Zone Lymphoma

Active Not Recruiting
NCT07842523Phase 2

Obinutuzumab in Systemic Sclerosis

Not Yet Recruiting
NCT06284122Phase 3

Study of Mosunetuzumab Plus Lenalidomide Compared to Anti-CD20 Anti-body + Chemotherapy in Follicular Lymphoma FLIPI2-5

Active Not Recruiting

Drug Details

Intervention Type
BIOLOGICAL
Total Trials
265