Success Metrics

Clinical Success Rate
72.3%

Based on 81 completed trials

Completion Rate
72%(81/112)
Active Trials
114(44%)
Results Posted
90%(73 trials)
Terminated
31(12%)

Phase Distribution

Ph not_applicable
2
1%
Ph phase_3
40
15%
Ph phase_4
1
0%
Ph phase_2
119
46%
Ph phase_1
91
35%

Phase Distribution

91

Early Stage

119

Mid Stage

41

Late Stage

Phase Distribution253 total trials
Phase 1Safety & dosage
91(36.0%)
Phase 2Efficacy & side effects
119(47.0%)
Phase 3Large-scale testing
40(15.8%)
Phase 4Post-market surveillance
1(0.4%)
N/ANon-phased studies
2(0.8%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

68.1%

81 of 119 finished

Non-Completion Rate

31.9%

38 ended early

Currently Active

114

trials recruiting

Total Trials

261

all time

Status Distribution
Active(136)
Completed(81)
Terminated(38)
Other(6)

Detailed Status

Completed81
Recruiting61
Active, not recruiting53
Terminated31
Not yet recruiting22
Withdrawn7

Development Timeline

Analytics

Development Status

Total Trials
261
Active
114
Success Rate
72.3%
Most Advanced
Phase 4

Trials by Phase

Phase 191 (36.0%)
Phase 2119 (47.0%)
Phase 340 (15.8%)
Phase 41 (0.4%)
N/A2 (0.8%)

Trials by Status

suspended10%
active_not_recruiting5320%
not_yet_recruiting228%
terminated3112%
unknown52%
completed8131%
recruiting6123%
withdrawn73%

Recent Activity

Clinical Trials (261)

Showing 20 of 261 trialsScroll for more
NCT07003295Phase 2

Testing the Anti-cancer Drug, Glofitamab, in Patients With Mantle Cell Lymphoma (A Type of Blood Cancer) Whose Disease Returned After CAR-T Cell Therapy

Recruiting
NCT04269902Phase 3

Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

Recruiting
NCT06967610Phase 2

Phase II Study of Combined Pirtobrutinib, Venetoclax and Obinutuzumab (PVO) Time-limited Treatment for Patients With Recurrent Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL).

Recruiting
NCT03075696Phase 1

A Dose Escalation Study of Glofitamab (RO7082859) as a Single Agent and in Combination With Obinutuzumab, Administered After a Fixed, Single Pre-treatment Dose of Obinutuzumab in Participants With Relapsed/Refractory B-cell Non-hodgkin's Lymphoma

Active Not Recruiting
NCT06943872Phase 3

A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)

Recruiting
NCT03223610Phase 1

Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid (ViPOR) in Relapsed/Refractory B-cell Lymphoma

Recruiting
NCT07724457Phase 2

Testing the Addition of a New Anti-Cancer Drug, Glofitamab to Usual Chemotherapy for Burkitt and Double Hit Lymphoma

Not Yet Recruiting
NCT06252675Phase 2

Glofitamab With Pirtobrutinib for Relapsed or Refractory Mantle Cell Lymphoma

Recruiting
NCT06970743Phase 3

A Study of BGB-16673 Compared to Investigator's Choice in Participants With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Previously Exposed to Covalent Bruton Tyrosine Kinase (BTK) Inhibitors

Active Not Recruiting
NCT06634589Phase 1

A Study to Investigate Safety and Effectiveness of BGB-16673 in Combination With Other Agents in Participants With Relapsed or Refractory B-Cell Malignancies

Recruiting
NCT07721363Phase 2

Obinutuzumab for Systemic Lupus Erythematosus Pure Membranous Nephropathy: a Phase II Trial

Not Yet Recruiting
NCT05100862Phase 3

A Study of Zanubrutinib Plus Anti-CD20 Versus Lenalidomide Plus Rituximab in Participants With Relapsed/Refractory Follicular or Marginal Zone Lymphoma

Active Not Recruiting
NCT05861050Phase 1

Glofitamab With Obinutuzumab, Venetoclax, and Lenalidomide for the Treatment of Patients With Newly Diagnosed High Risk Mantle Cell Lymphoma

Recruiting
NCT06765317Phase 2

A Study of Glofitamab-based Treatment in People With Diffuse Large B-cell Lymphoma

Recruiting
NCT06073821Phase 3

Study of Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Obinutuzumab in Participants With Chronic Lymphocytic Leukemia (CLL)

Active Not Recruiting
NCT07719855Phase 3

A Multicenter, Prospective, Open-Label, Randomized Controlled Clinical Study of Orelabrutinib Combined With Obinutuzumab and Lenalidomide Versus Obinutuzumab Plus Chemotherapy for Treatment-Naive Follicular Lymphoma

Not Yet Recruiting
NCT06849713Phase 2

Zanubrutinib, Obinutuzumab, Sonrotoclax (BOSon) or BGB-16673, Obinutuzumab, Sonrotoclax (DOSon) in TN CLL/SLL

Recruiting
NCT07719556Phase 2

Orelabrutinib Combined With Obinutuzumab and Short-Course Venetoclax in Patients With Treatment-Naïve Mantle Cell Lymphoma (MCL)

Recruiting
NCT04221477Phase 3

A Study to Evaluate the Efficacy and Safety of Obinutuzumab in Participants With ISN/RPS 2003 Class III or IV Lupus Nephritis

Active Not Recruiting
NCT06806033Phase 2

A Study to Evaluate the Optimization of the Cytokine Release Syndrome Profile for Glofitamab in Combination With Gemcitabine Plus Oxaliplatin in Participants With Relapsed/Refractory Aggressive B-Cell Non-Hodgkin's Lymphoma

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
261