Success Metrics

Clinical Success Rate
71.8%

Based on 79 completed trials

Completion Rate
72%(79/110)
Active Trials
114(46%)
Results Posted
90%(71 trials)
Terminated
31(12%)

Phase Distribution

Ph phase_1
91
37%
Ph phase_2
109
44%
Ph phase_4
1
0%
Ph phase_3
38
15%
Ph not_applicable
2
1%

Phase Distribution

91

Early Stage

109

Mid Stage

39

Late Stage

Phase Distribution241 total trials
Phase 1Safety & dosage
91(37.8%)
Phase 2Efficacy & side effects
109(45.2%)
Phase 3Large-scale testing
38(15.8%)
Phase 4Post-market surveillance
1(0.4%)
N/ANon-phased studies
2(0.8%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

67.5%

79 of 117 finished

Non-Completion Rate

32.5%

38 ended early

Currently Active

114

trials recruiting

Total Trials

249

all time

Status Distribution
Active(127)
Completed(79)
Terminated(38)
Other(5)

Detailed Status

Completed79
Recruiting67
Active, not recruiting47
Terminated31
Not yet recruiting13
Withdrawn7

Development Timeline

Analytics

Development Status

Total Trials
249
Active
114
Success Rate
71.8%
Most Advanced
Phase 4

Trials by Phase

Phase 191 (37.8%)
Phase 2109 (45.2%)
Phase 338 (15.8%)
Phase 41 (0.4%)
N/A2 (0.8%)

Trials by Status

completed7932%
withdrawn73%
recruiting6727%
unknown52%
active_not_recruiting4719%
terminated3112%
not_yet_recruiting135%

Recent Activity

Clinical Trials (249)

Showing 20 of 249 trialsScroll for more
NCT05896163Phase 1

A Study to Learn About the Effects of Two Study Medicines (Maplirpacept [PF-07901801] And Glofitamab) When Given Together In People With Relapsed Or Refractory Diffuse Large B Cell Lymphoma.

Terminated
NCT03322865Phase 2

Obinutuzumab in Marginal Zone Lymphoma

Active Not Recruiting
NCT06191744Phase 3

Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral Lenalidomide (R2) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Previously Untreated Follicular Lymphoma

Recruiting
NCT05376319Phase 2

PR3-AAV Resilient Remission or PRRR

Terminated
NCT05848765Phase 2

Relapsed Follicular Lymphoma Randomised Trial Against Standard ChemoTherapy

Recruiting
NCT06084936Phase 3

A Study to Evaluate Glofitamab as a Single Agent vs. Investigator's Choice in Participants With Relapsed/Refractory Mantle Cell Lymphoma

Recruiting
NCT05039619Phase 2

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Participants

Recruiting
NCT05533775Phase 1

A Study to Evaluate Glofitamab Monotherapy and Glofitamab + Chemoimmunotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Mature B-Cell Non-Hodgkin Lymphoma

Recruiting
NCT04269902Phase 3

Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

Recruiting
NCT06649812Phase 2

Testing the Effectiveness of a Combination Targeted Therapy (ViPOR) for Patients With Relapsed and/or Refractory Aggressive B-cell Lymphoma

Recruiting
NCT06624085Phase 1

A Study Evaluating the Safety and Efficacy of Glofitamab + Gemcitabine + Oxaliplatin in U.S. Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Recruiting
NCT03701282Phase 3

Assessing the Ability of Combination Treatment With Venetoclax to Permit Time Limited Therapy in Chronic Lymphocytic Leukemia

Active Not Recruiting
NCT03269669Phase 2

Obinutuzumab With or Without Umbralisib, Lenalidomide, or Combination Chemotherapy in Treating Patients With Relapsed or Refractory Grade I-IIIa Follicular Lymphoma

Active Not Recruiting
NCT03737981Phase 3

Testing the Addition of a New Anti-cancer Drug, Venetoclax, to the Usual Treatment (Ibrutinib and Obinutuzumab) in Untreated, Older Patients With Chronic Lymphocytic Leukemia

Active Not Recruiting
NCT03075696Phase 1

A Dose Escalation Study of Glofitamab (RO7082859) as a Single Agent and in Combination With Obinutuzumab, Administered After a Fixed, Single Pre-treatment Dose of Obinutuzumab in Participants With Relapsed/Refractory B-cell Non-hodgkin's Lymphoma

Active Not Recruiting
NCT05536349Phase 2

Time-limited Triplet Combination of Pirtobrutinib, Venetoclax, and Obinutuzumab for Patients With Treatment-naïve Chronic Lymphocytic Leukemia (CLL) or Richter Transformation (RT)

Recruiting
NCT04608318Phase 3

Ibrutinib Monotherapy Versus Fixed-duration Venetoclax Plus Obinutuzumab Versus Fixed-duration Ibrutinib Plus Venetoclax in Patients With Previously Untreated Chronic Lymphocytic Leukaemia (CLL)

Active Not Recruiting
NCT06765317Phase 2

A Study of Glofitamab-based Treatment in People With Diffuse Large B-cell Lymphoma

Recruiting
NCT04739813Phase 1

Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid in Combination With Polatuzumab (ViPOR-P) in Relapsed/Refractory B-cell Lymphoma

Recruiting
NCT03863184Phase 2

Acalabrutinib-Lenalidomide-Rituximab in Patients With Untreated MCL

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
249