Success Metrics

Clinical Success Rate
72.3%

Based on 81 completed trials

Completion Rate
72%(81/112)
Active Trials
114(44%)
Results Posted
90%(73 trials)
Terminated
31(12%)

Phase Distribution

Ph phase_3
40
15%
Ph phase_1
91
35%
Ph not_applicable
2
1%
Ph phase_2
119
46%
Ph phase_4
1
0%

Phase Distribution

91

Early Stage

119

Mid Stage

41

Late Stage

Phase Distribution253 total trials
Phase 1Safety & dosage
91(36.0%)
Phase 2Efficacy & side effects
119(47.0%)
Phase 3Large-scale testing
40(15.8%)
Phase 4Post-market surveillance
1(0.4%)
N/ANon-phased studies
2(0.8%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

68.1%

81 of 119 finished

Non-Completion Rate

31.9%

38 ended early

Currently Active

114

trials recruiting

Total Trials

261

all time

Status Distribution
Active(136)
Completed(81)
Terminated(38)
Other(6)

Detailed Status

Completed81
Recruiting58
Active, not recruiting56
Terminated31
Not yet recruiting22
Withdrawn7

Development Timeline

Analytics

Development Status

Total Trials
261
Active
114
Success Rate
72.3%
Most Advanced
Phase 4

Trials by Phase

Phase 191 (36.0%)
Phase 2119 (47.0%)
Phase 340 (15.8%)
Phase 41 (0.4%)
N/A2 (0.8%)

Trials by Status

unknown52%
completed8131%
not_yet_recruiting228%
active_not_recruiting5621%
recruiting5822%
terminated3112%
suspended10%
withdrawn73%

Recent Activity

Clinical Trials (261)

Showing 20 of 261 trialsScroll for more
NCT06943872Phase 3

A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)

Recruiting
NCT02846623Phase 2

Atezolizumab, Obinutuzumab, and Venetoclax in Treating Patients With Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, or Relapsed or Refractory Richter Syndrome

Active Not Recruiting
NCT05169515Phase 1

A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Mosunetuzumab or Glofitamab in Combination With CC-220 and/or CC-99282 in Participants With B-Cell Non-Hodgkin Lymphoma

Active Not Recruiting
NCT06970743Phase 3

A Study of BGB-16673 Compared to Investigator's Choice in Participants With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Previously Exposed to Covalent Bruton Tyrosine Kinase (BTK) Inhibitors

Active Not Recruiting
NCT06073821Phase 3

Study of Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Obinutuzumab in Participants With Chronic Lymphocytic Leukemia (CLL)

Active Not Recruiting
NCT06624085Phase 1

A Study Evaluating the Safety and Efficacy of Glofitamab + Gemcitabine + Oxaliplatin in U.S. Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Active Not Recruiting
NCT04269902Phase 3

Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

Recruiting
NCT06649812Phase 2

Testing the Effectiveness of a Combination Targeted Therapy (ViPOR) for Patients With Relapsed and/or Refractory Aggressive B-cell Lymphoma

Recruiting
NCT03223610Phase 1

Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid (ViPOR) in Relapsed/Refractory B-cell Lymphoma

Recruiting
NCT05100862Phase 3

A Study of Zanubrutinib Plus Anti-CD20 Versus Lenalidomide Plus Rituximab in Participants With Relapsed/Refractory Follicular or Marginal Zone Lymphoma

Active Not Recruiting
NCT05039619Phase 2

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Participants

Recruiting
NCT06084936Phase 3

A Study to Evaluate Glofitamab as a Single Agent vs. Investigator's Choice in Participants With Relapsed/Refractory Mantle Cell Lymphoma

Recruiting
NCT05533775Phase 1

A Study to Evaluate Glofitamab Monotherapy and Glofitamab + Chemoimmunotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Mature B-Cell Non-Hodgkin Lymphoma

Recruiting
NCT06191744Phase 3

Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral Lenalidomide (R2) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Previously Untreated Follicular Lymphoma

Active Not Recruiting
NCT06849713Phase 2

Zanubrutinib, Obinutuzumab, Sonrotoclax (BOSon) or BGB-16673, Obinutuzumab, Sonrotoclax (DOSon) in TN CLL/SLL

Recruiting
NCT03737981Phase 3

Testing the Addition of a New Anti-cancer Drug, Venetoclax, to the Usual Treatment (Ibrutinib and Obinutuzumab) in Untreated, Older Patients With Chronic Lymphocytic Leukemia

Active Not Recruiting
NCT03701282Phase 3

Assessing the Ability of Combination Treatment With Venetoclax to Permit Time Limited Therapy in Chronic Lymphocytic Leukemia

Active Not Recruiting
NCT07003295Phase 2

Testing the Anti-cancer Drug, Glofitamab, in Patients With Mantle Cell Lymphoma (A Type of Blood Cancer) Whose Disease Returned After CAR-T Cell Therapy

Recruiting
NCT06967610Phase 2

Phase II Study of Combined Pirtobrutinib, Venetoclax and Obinutuzumab (PVO) Time-limited Treatment for Patients With Recurrent Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL).

Recruiting
NCT03075696Phase 1

A Dose Escalation Study of Glofitamab (RO7082859) as a Single Agent and in Combination With Obinutuzumab, Administered After a Fixed, Single Pre-treatment Dose of Obinutuzumab in Participants With Relapsed/Refractory B-cell Non-hodgkin's Lymphoma

Active Not Recruiting

Drug Details

Intervention Type
BIOLOGICAL
Total Trials
261