Success Metrics

Clinical Success Rate
71.8%

Based on 509 completed trials

Completion Rate
72%(509/709)
Active Trials
451(34%)
Results Posted
92%(466 trials)
Terminated
200(15%)

Phase Distribution

Ph phase_1
516
39%
Ph not_applicable
12
1%
Ph phase_2
621
46%
Ph phase_3
118
9%
Ph early_phase_1
26
2%
Ph phase_4
10
1%

Phase Distribution

542

Early Stage

621

Mid Stage

128

Late Stage

Phase Distribution1303 total trials
Early Phase 1First-in-human
26(2.0%)
Phase 1Safety & dosage
516(39.6%)
Phase 2Efficacy & side effects
621(47.7%)
Phase 3Large-scale testing
118(9.1%)
Phase 4Post-market surveillance
10(0.8%)
N/ANon-phased studies
12(0.9%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

64.9%

509 of 784 finished

Non-Completion Rate

35.1%

275 ended early

Currently Active

451

trials recruiting

Total Trials

1,338

all time

Status Distribution
Active(475)
Completed(509)
Terminated(275)
Other(79)

Detailed Status

Completed509
Active, not recruiting267
Terminated200
Recruiting184
Withdrawn75
unknown66

Development Timeline

Analytics

Development Status

Total Trials
1338
Active
451
Success Rate
71.8%
Most Advanced
Phase 4

Trials by Phase

Early Phase 126 (2.0%)
Phase 1516 (39.6%)
Phase 2621 (47.7%)
Phase 3118 (9.1%)
Phase 410 (0.8%)
N/A12 (0.9%)

Trials by Status

unknown665%
not_yet_recruiting191%
enrolling_by_invitation50%
recruiting18414%
completed50938%
suspended131%
terminated20015%
active_not_recruiting26720%
withdrawn756%

Recent Activity

Clinical Trials (1,338)

Showing 20 of 1,338 trialsScroll for more
NCT02194738Not Applicable

Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The ALCHEMIST Screening Trial)

Active Not Recruiting
NCT03604991Phase 2

Nivolumab and Ipilimumab in Treating Patients With Esophageal and Gastroesophageal Junction Adenocarcinoma Undergoing Surgery

Suspended
NCT03383458Phase 3

A Study of Nivolumab in Participants With Hepatocellular Carcinoma Who Are at High Risk of Recurrence After Curative Hepatic Resection or Ablation

Active Not Recruiting
NCT05111574Phase 2

Using Nivolumab Alone or With Cabozantinib to Prevent Mucosal Melanoma Return After Surgery

Active Not Recruiting
NCT06866262Phase 1

Inulin Gel in Combination With Ipilimumab and Nivolumab for the Treatment of Metastatic or Locally Advanced Kidney Cell Cancer, ICON Trial

Recruiting
NCT02465060Phase 2

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

Active Not Recruiting
NCT05136196Phase 2

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

Recruiting
NCT05112601Phase 2

Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma

Recruiting
NCT03816332Phase 1

Tacrolimus, Nivolumab, and Ipilimumab in Treating Kidney Transplant Recipients With Selected Unresectable or Metastatic Cancers

Active Not Recruiting
NCT03811015Phase 3

Testing Immunotherapy Versus Observation in Patients With HPV Throat Cancer

Active Not Recruiting
NCT05675410Phase 3

A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

Recruiting
NCT04912765Phase 2

Neoantigen Dendritic Cell Vaccine and Nivolumab in HCC and Liver Metastases From CRC

Recruiting
NCT02314169Phase 2

Nivolumab With or Without Ipilimumab in Treating Patients With Refractory Metastatic Anal Canal Cancer

Active Not Recruiting
NCT04339738Phase 2

Testing the Addition of Nivolumab to Chemotherapy in Treatment of Soft Tissue Sarcoma

Active Not Recruiting
NCT05568095Phase 3

A Clinical Trial of a New Combination Treatment, Domvanalimab and Zimberelimab, Plus Chemotherapy, for People With an Upper Gastrointestinal Tract Cancer That Cannot be Removed With Surgery That Has Spread to Other Parts of the Body

Active Not Recruiting
NCT03233711Phase 3

Nivolumab After Combined Modality Therapy in Treating Patients With High Risk Stage II-IIIB Anal Cancer

Active Not Recruiting
NCT02595944Phase 3

Nivolumab After Surgery and Chemotherapy in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer (An ALCHEMIST Treatment Trial)

Active Not Recruiting
NCT02339571Phase 2

A Phase II/III Trial of Nivolumab, Ipilimumab, and GM-CSF in Patients With Advanced Melanoma

Active Not Recruiting
NCT02453620Phase 1

Entinostat, Nivolumab, and Ipilimumab in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery or Locally Advanced or Metastatic HER2-Negative Breast Cancer

Active Not Recruiting
NCT03055013Phase 3

Nivolumab in Treating Patients With Localized Kidney Cancer Undergoing Nephrectomy

Active Not Recruiting

Drug Details

Intervention Type
BIOLOGICAL
Total Trials
1,338