Success Metrics

Clinical Success Rate
72.1%

Based on 504 completed trials

Completion Rate
72%(504/699)
Active Trials
453(34%)
Results Posted
91%(457 trials)
Terminated
195(15%)

Phase Distribution

Ph phase_4
10
1%
Ph early_phase_1
26
2%
Ph phase_1
513
39%
Ph not_applicable
12
1%
Ph phase_2
620
47%
Ph phase_3
115
9%

Phase Distribution

539

Early Stage

620

Mid Stage

125

Late Stage

Phase Distribution1296 total trials
Early Phase 1First-in-human
26(2.0%)
Phase 1Safety & dosage
513(39.6%)
Phase 2Efficacy & side effects
620(47.8%)
Phase 3Large-scale testing
115(8.9%)
Phase 4Post-market surveillance
10(0.8%)
N/ANon-phased studies
12(0.9%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

65.3%

504 of 772 finished

Non-Completion Rate

34.7%

268 ended early

Currently Active

453

trials recruiting

Total Trials

1,329

all time

Status Distribution
Active(479)
Completed(504)
Terminated(268)
Other(78)

Detailed Status

Completed504
Active, not recruiting261
Terminated195
Recruiting192
Withdrawn73
unknown68

Development Timeline

Analytics

Development Status

Total Trials
1329
Active
453
Success Rate
72.1%
Most Advanced
Phase 4

Trials by Phase

Early Phase 126 (2.0%)
Phase 1513 (39.6%)
Phase 2620 (47.8%)
Phase 3115 (8.9%)
Phase 410 (0.8%)
N/A12 (0.9%)

Trials by Status

suspended101%
active_not_recruiting26120%
enrolling_by_invitation50%
completed50438%
withdrawn735%
not_yet_recruiting212%
terminated19515%
recruiting19214%
unknown685%

Recent Activity

Clinical Trials (1,329)

Showing 20 of 1,329 trialsScroll for more
NCT07645118Phase 2

Brachytherapy Followed by Nivolumab Prior to Surgery in Rectal Cancer

Not Yet Recruiting
NCT07527858Phase 2

Study of Denikitug (GS-1811) Given Alone or With Nivolumab or With Chemotherapy in Adults With Advanced Colorectal Cancer

Recruiting
NCT05904080Phase 2

Testing Nivolumab and Ipilimumab Immunotherapy With or Without the Targeted Drug Cabozantinib in Recurrent, Metastatic, or Incurable Nasopharyngeal Cancer

Recruiting
NCT03681561Phase 1

Nivolumab With Ruxolitinib in Relapsed or Refractory Classical Hodgkin Lymphoma

Recruiting
NCT07392892Phase 2

Symbiotic-GI-16: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Gastroesophageal Cancer

Recruiting
NCT04729322Phase 2

Fecal Microbiota Transplant and Re-introduction of Anti-PD-1 Therapy (Pembrolizumab or Nivolumab) for the Treatment of Metastatic Colorectal Cancer in Anti-PD-1 Non-responders

Active Not Recruiting
NCT05896839Phase 1

Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metastatic Skin Cancer

Recruiting
NCT03104439Phase 2

Nivolumab and Ipilimumab and Radiation Therapy in MSS and MSI High Colorectal and Pancreatic Cancer

Active Not Recruiting
NCT04546399Phase 2

A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)

Recruiting
NCT07405164Phase 3

Extension Study for Participants in Studies That Include Belzutifan (MK-6482-043/LITESPARK-043)

Recruiting
NCT05112601Phase 2

Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma

Recruiting
NCT05327270Phase 1

Non-randomized, Open-label Study of Intralesional Nivolumab for High Risk Oral Premalignant Lesions

Active Not Recruiting
NCT06064097Phase 2

A Study Using Nivolumab, in Combination With Chemotherapy Drugs to Treat Nasopharyngeal Carcinoma (NPC)

Recruiting
NCT07541170Phase 3

A Study to Evaluate the Efficacy and Safety of Divarasib Compared With Investigator's Choice of Immunotherapy or Observation in Participants With Resected Stage II-III KRAS G12C-Positive Non-Small Cell Lung Cancer (NSCLC)

Not Yet Recruiting
NCT05675410Phase 3

A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

Recruiting
NCT05987241Phase 2

Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study

Recruiting
NCT05076760Phase 1

MEM-288 Oncolytic Virus Alone and in Combination With Standard of Care Therapy in Advanced Solid Tumors

Recruiting
NCT03866382Phase 2

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

Recruiting
NCT02910700Phase 2

Nivolumab With Trametinib and Dabrafenib, or Encorafenib and Binimetinib in Treating Patients With BRAF Mutated Metastatic or Unresectable Stage III-IV Melanoma

Active Not Recruiting
NCT04495257Phase 1

A Study of APX005M in Combination With Nivolumab and Ipilimumab in Treatment Naïve Patients With Advanced Melanoma or Renal Cell Carcinoma (RCC)

Completed

Drug Details

Intervention Type
DRUG
Total Trials
1,329