Success Metrics

Clinical Success Rate
71.9%

Based on 519 completed trials

Completion Rate
72%(519/722)
Active Trials
446(33%)
Results Posted
91%(473 trials)
Terminated
203(15%)

Phase Distribution

Ph phase_2
624
46%
Ph phase_3
118
9%
Ph early_phase_1
26
2%
Ph phase_1
520
39%
Ph phase_4
10
1%
Ph not_applicable
12
1%

Phase Distribution

546

Early Stage

624

Mid Stage

128

Late Stage

Phase Distribution1310 total trials
Early Phase 1First-in-human
26(2.0%)
Phase 1Safety & dosage
520(39.7%)
Phase 2Efficacy & side effects
624(47.6%)
Phase 3Large-scale testing
118(9.0%)
Phase 4Post-market surveillance
10(0.8%)
N/ANon-phased studies
12(0.9%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

65.1%

519 of 797 finished

Non-Completion Rate

34.9%

278 ended early

Currently Active

446

trials recruiting

Total Trials

1,345

all time

Status Distribution
Active(468)
Completed(519)
Terminated(278)
Other(80)

Detailed Status

Completed519
Active, not recruiting264
Terminated203
Recruiting182
Withdrawn75
unknown65

Development Timeline

Analytics

Development Status

Total Trials
1345
Active
446
Success Rate
71.9%
Most Advanced
Phase 4

Trials by Phase

Early Phase 126 (2.0%)
Phase 1520 (39.7%)
Phase 2624 (47.6%)
Phase 3118 (9.0%)
Phase 410 (0.8%)
N/A12 (0.9%)

Trials by Status

recruiting18214%
suspended151%
enrolling_by_invitation60%
terminated20315%
unknown655%
withdrawn756%
active_not_recruiting26420%
completed51939%
not_yet_recruiting161%

Recent Activity

Clinical Trials (1,345)

Showing 20 of 1,345 trialsScroll for more
NCT06049576Phase 1

Nivolumab and Ipilimumab With and Without Camu Camu for the Treatment of Patients With Metastatic Renal Cell Carcinoma

Suspended
NCT03576417Phase 3

A Trial Evaluating the Addition of Nivolumab to Cisplatin-RT for Treatment of Cancers of the Head and Neck

Active Not Recruiting
NCT02379520Phase 1

HPV-16/18 E6/E7-Specific T Lymphocytes, Relapsed HPV-Associated Cancers, HESTIA

Completed
NCT03258567Phase 2

Nivolumab in Epstein-Barr Virus (EBV)-Positive Lymphoproliferative Disorders and EBV-Positive Non-HodgkinLymphomas

Recruiting
NCT05675410Phase 3

A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

Recruiting
NCT03719131Phase 2

Rituximab and Hyaluronidase Human in Patients With Advanced Melanoma Undergoing Nivolumab and Ipilimumab Therapy

Completed
NCT07226856Phase 2

BMS-986340 in Combination With Nivolumab, Gemcitabine and Nab-paclitaxel for the Treatment of Metastatic and Recurrent Pancreatic Adenocarcinoma

Recruiting
NCT06265285Phase 2

Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program

Recruiting
NCT06325683Phase 2

Anti-Lag-3 (Relatlimab) and Anti-PD-1 Blockade (Nivolumab) Versus Standard of Care (Lomustine) for the Treatment of Patients With Recurrent Glioblastoma

Suspended
NCT04991025Phase 2

Adding Certolizumab to Chemotherapy + Nivolumab in People Who Have Lung Cancer That Can Be Treated With Surgery

Recruiting
NCT05203172Phase 4

The FLOTILLA Study: Providing Continued Access to The Study Medicines Encorafenib and Binimetinib for Participants in Prior Clinical Trials

Recruiting
NCT05677490Phase 3

mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma

Recruiting
NCT06203600Phase 2

Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial

Recruiting
NCT05176483Phase 1

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

Recruiting
NCT04759586Phase 3

Nivolumab in Combination With Chemo-Immunotherapy for the Treatment of Newly Diagnosed Primary Mediastinal B-Cell Lymphoma

Active Not Recruiting
NCT02224781Phase 3

Dabrafenib and Trametinib Followed by Ipilimumab and Nivolumab or Ipilimumab and Nivolumab Followed by Dabrafenib and Trametinib in Treating Patients With Stage III-IV BRAFV600 Melanoma

Active Not Recruiting
NCT03793166Phase 3

Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer, The PDIGREE Study

Active Not Recruiting
NCT03595124Phase 2

A Study to Compare Treatments for a Type of Kidney Cancer Called TFE/Translocation Renal Cell Carcinoma (tRCC)

Active Not Recruiting
NCT02465060Phase 2

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

Active Not Recruiting
NCT06365619Phase 2

Neoadjuvant Ipilimumab/Nivolumab for Patients With Recurrent, High Risk, Resectable Melanoma

Recruiting

Drug Details

Intervention Type
BIOLOGICAL
Total Trials
1,345