Success Metrics

Clinical Success Rate
84.4%

Based on 65 completed trials

Completion Rate
84%(65/77)
Active Trials
9(9%)
Results Posted
80%(52 trials)
Terminated
12(12%)

Phase Distribution

Ph phase_3
15
15%
Ph phase_4
9
9%
Ph phase_2
25
25%
Ph phase_1
29
29%

Phase Distribution

29

Early Stage

25

Mid Stage

24

Late Stage

Phase Distribution78 total trials
Phase 1Safety & dosage
29(37.2%)
Phase 2Efficacy & side effects
25(32.1%)
Phase 3Large-scale testing
15(19.2%)
Phase 4Post-market surveillance
9(11.5%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

81.3%

65 of 80 finished

Non-Completion Rate

18.8%

15 ended early

Currently Active

9

trials recruiting

Total Trials

99

all time

Status Distribution
Active(13)
Completed(65)
Terminated(15)
Other(6)

Detailed Status

Completed65
Terminated12
unknown6
Recruiting5
Active, not recruiting4
Not yet recruiting4

Development Timeline

Analytics

Development Status

Total Trials
99
Active
9
Success Rate
84.4%
Most Advanced
Phase 4

Trials by Phase

Phase 129 (37.2%)
Phase 225 (32.1%)
Phase 315 (19.2%)
Phase 49 (11.5%)

Trials by Status

withdrawn33%
recruiting55%
terminated1212%
active_not_recruiting44%
completed6566%
not_yet_recruiting44%
unknown66%

Recent Activity

Clinical Trials (99)

Showing 20 of 99 trialsScroll for more
NCT04619680Phase 4

The Study of the Use of Nintedanib in Slowing Lung Disease in Patients With Fibrotic or Non-Fibrotic Interstitial Lung Disease Related to COVID-19

Completed
NCT05503030

Correlation Between Changes in Lung Function and Changes in Cough and Dyspnoea in Nintedanib-treated Connective Tissue Disease Interstitial Lung Disease (CTD-ILD) Patients

Active Not Recruiting
NCT06485635

Real-life-persistence to Antifibrotic Treatments

Completed
NCT06297096Phase 3

Study of the Efficacy of Nintedanib+Tocilizumab in Patients With Systemic Sclerosis and Interstitial Lung Disease

Recruiting
NCT03377023Phase 1

Phase I/II Study of Nivolumab and Ipilimumab Combined With Nintedanib in Non Small Cell Lung Cancer

Active Not Recruiting
NCT04325217

Post-marketing Surveillance on Long Term Use of Ofev Capsules in Systemic Scleroderma Associated Interstitial Lung Disease (SSc-ILD) in Japan

Active Not Recruiting
NCT01658462Phase 2

Phase II Study of Docetaxel +/- Nintedanib in Breast Cancer

Completed
NCT04976036Phase 2

Efficacy of Nintedanib for Treatment of Epistaxis in Hereditary Hemorrhagic Telangiectasia (HHT) Patients

Recruiting
NCT07454291Phase 1

A Phase 1, Open-Label Study to Evaluate Pharmacokinetics and Drug-drug Interactions of ENV-101 (Taladegib) in Healthy Participants

Not Yet Recruiting
NCT07335562Phase 3

A Study to Compare the Efficacy and Safety of BMS-986353 (Zolacaptagene- Autoleucel / Zola-cel), CD19-CAR T Cells, Versus Standard of Care in Participants With Active Systemic Sclerosis

Not Yet Recruiting
NCT05799755Phase 4

Myositis Interstitial Lung Disease Nintedanib Trial

Completed
NCT04559581

Post-marketing Surveillance of Ofev Capsules in Chronic Fibrosing Interstitial Lung Diseases With a Progressive Phenotype in Japan

Completed
NCT02856425Phase 1

Trial Of Pembrolizumab And Nintedanib

Completed
NCT03805477Phase 2

Nintedanib in Patients With Bronchiolitis Obliterans Syndrome Following Hematopoietic Stem Cell Transplantation

Recruiting
NCT06070610Phase 1

A Study in Healthy Men to Test Whether BI 1015550 Influences the Amount of Nintedanib and Pirfenidone in the Blood

Completed
NCT05151640

INCHANGE - Nintedanib for Changes in Cough and Dyspnea in Patients Suffering From Chronic Fibrosing Interstitial Lung Disease With a Progressive Phenotype in Everyday Clinical Practice: a Real-world Evaluation

Completed
NCT03513484Phase 1

Nintedanib and Azacitidine in Treating Participants With HOX Gene Overexpression Relapsed or Refractory Acute Myeloid Leukemia

Active Not Recruiting
NCT07015398Phase 1

A Study of the Pharmacokinetic Interaction Between Pirfenidone, Nintedanib, and Nalbuphine Extended Release (NAL ER) in Healthy Participants

Completed
NCT02863055Phase 2

Nintedanib as Switch Maintenance Treatment of Pleural Malignant Mesothelioma

Terminated
NCT07162961Phase 3

Nintedanib for Improving Reproductive Outcomes in Adenomyosis

Not Yet Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
99