Success Metrics

Clinical Success Rate
85.7%

Based on 12 completed trials

Completion Rate
86%(12/14)
Active Trials
9(30%)
Results Posted
33%(4 trials)
Terminated
2(7%)

Phase Distribution

Ph phase_1
3
10%
Ph not_applicable
8
27%
Ph phase_2
16
53%
Ph phase_3
2
7%
Ph early_phase_1
1
3%

Phase Distribution

4

Early Stage

16

Mid Stage

2

Late Stage

Phase Distribution30 total trials
Early Phase 1First-in-human
1(3.3%)
Phase 1Safety & dosage
3(10.0%)
Phase 2Efficacy & side effects
16(53.3%)
Phase 3Large-scale testing
2(6.7%)
N/ANon-phased studies
8(26.7%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

80.0%

12 of 15 finished

Non-Completion Rate

20.0%

3 ended early

Currently Active

9

trials recruiting

Total Trials

30

all time

Status Distribution
Active(9)
Completed(12)
Terminated(3)
Other(6)

Detailed Status

Completed12
Recruiting8
unknown6
Terminated2
Active, not recruiting1
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
30
Active
9
Success Rate
85.7%
Most Advanced
Phase 3

Trials by Phase

Early Phase 11 (3.3%)
Phase 13 (10.0%)
Phase 216 (53.3%)
Phase 32 (6.7%)
N/A8 (26.7%)

Trials by Status

active_not_recruiting13%
terminated27%
unknown620%
withdrawn13%
recruiting827%
completed1240%

Recent Activity

9 active trials
Showing 5 of 30
active_not_recruitingphase_2

Tolerance and Efficacy Nicotinamide (Vitamin B3) in Dominant Optic Atrophy OPA1

NCT06007391
recruitingearly_phase_1

Pilot Trial of Supplemental Vitamin A and Nicotinamide

NCT05702398
recruitingphase_2

Effects of Nicotinamide in Patients With Chronic Lymphocytic Leukemia With History of Non-melanoma Skin Cancers

NCT04844528
recruitingphase_2

Study of the Efficacy and Safety of Nicotinamide in Patients With Liver Fibrosis (NICOFIB)

NCT06599918
recruitingphase_2

Comparisons of NAD Precursors for Neuroenhancement in Glaucoma Patients

NCT06991712
View all 30 trials

Clinical Trials (30)

Showing 20 of 30 trialsScroll for more
NCT06007391Phase 2

Tolerance and Efficacy Nicotinamide (Vitamin B3) in Dominant Optic Atrophy OPA1

Active Not Recruiting
NCT05702398Early Phase 1

Pilot Trial of Supplemental Vitamin A and Nicotinamide

Recruiting
NCT04844528Phase 2

Effects of Nicotinamide in Patients With Chronic Lymphocytic Leukemia With History of Non-melanoma Skin Cancers

Recruiting
NCT06599918Phase 2

Study of the Efficacy and Safety of Nicotinamide in Patients With Liver Fibrosis (NICOFIB)

Recruiting
NCT06991712Phase 2

Comparisons of NAD Precursors for Neuroenhancement in Glaucoma Patients

Recruiting
NCT04055818Phase 1

A Study of Nicotinamide With Oral Tetrahydrouridine and Decitabine to Treat High Risk Sickle Cell Disease

Recruiting
NCT05955924Phase 3

Nicotinamide Chemoprevention for Keratinocyte Carcinoma in Solid Organ Transplant Recipients - Pivotal Trial

Recruiting
NCT04670081Phase 2

Efficacy and Safety of Psilocybin in Treatment-Resistant Major Depression

Completed
NCT06465602Phase 2

Nicotinamide Supplementation Improves Physical Performance in Older Adults at Risk of Falls

Recruiting
NCT03136705Phase 1

Healthy Combine Study

Completed
NCT03761511Phase 2

Study of the Efficacy and Safety of Nicotinamide in Patients With Friedreich Ataxia

Withdrawn
NCT03061474Phase 2

Nicotinamide as an Early Alzheimer's Disease Treatment

Completed
NCT05275738Not Applicable

The Glaucoma Nicotinamide Trial

Recruiting
NCT05916066Not Applicable

Nicotinamide and Glaucoma

Completed
NCT03769285Phase 2

Skin Cancer Prevention With Nicotinamide in Transplant Recipients - Pilot Trial

Unknown
NCT04751604Not Applicable

Improvement of the Nutritional Status Regarding Nicotinamide (Vitamin B3) and the Disease Course of COVID-19

Completed
NCT04012177Not Applicable

Nutritional Support and Prophylaxis Doses of Azithromycin for Pregnant Women - Mumta Pregnant Women Trial

Unknown
NCT03419364Phase 2

Study of Nicotinamide in Early Onset Preeclampsia

Completed
NCT04910230Not Applicable

Nicotinamide-based Supportive Therapy in Lymphopenia for Patients With COVID-19

Completed
NCT05017428Not Applicable

Absorption and Digestion Kinetics of Human Metabolites

Completed

Drug Details

Intervention Type
DRUG
Total Trials
30