Success Metrics

Clinical Success Rate

72.4%

Based on 21 completed trials

Completion Rate

72%(21/29)

Active Trials

1(3%)

Results Posted

57%(12 trials)

Terminated

8(21%)

Phase Distribution

Ph early_phase_1

Ph phase_3

28%

Ph phase_4

18%

Ph phase_2

18%

Ph phase_1

18%

Ph not_applicable

13%

Phase Distribution

Early Stage

Mid Stage

Late Stage

Phase Distribution38 total trials

Early Phase 1First-in-human

1(2.6%)

Phase 1Safety & dosage

7(18.4%)

Phase 2Efficacy & side effects

7(18.4%)

Phase 3Large-scale testing

11(28.9%)

Phase 4Post-market surveillance

7(18.4%)

N/ANon-phased studies

5(13.2%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

61.8%

21 of 34 finished

Non-Completion Rate

38.2%

13 ended early

Currently Active

trials recruiting

Total Trials

all time

Status Distribution

Active(1)

Completed(21)

Terminated(13)

Other(4)

Detailed Status

Completed21

Terminated8

Withdrawn5

unknown4

Recruiting1

Development Timeline

Analytics

Development Status

Total Trials

Active

Success Rate

72.4%

Most Advanced

Phase 4

Trials by Phase

Early Phase 11 (2.6%)

Phase 17 (18.4%)

Phase 27 (18.4%)

Phase 311 (28.9%)

Phase 47 (18.4%)

N/A5 (13.2%)

Trials by Status

withdrawn513%

completed2154%

terminated821%

recruiting13%

unknown410%

Recent Activity

1 active trials

Showing 5 of 39

terminatedphase_1

Clinical Trials (39)

Showing 20 of 39 trialsScroll for more

NCT00281671Phase 1

Nesiritide Use Following Cardiac Surgery in Infants

Terminated

NCT04455477

Nesiritide for Ventilated Congestive Heart Failure

Unknown

NCT00270829Phase 4

Renal Effects of Intrarenal Nesiritide

Terminated

NCT00204945Not Applicable

Catheterization Laboratory Study: Acute Responses in Diastolic Heart Failure

Completed

NCT00083772Phase 4

Use of Nesiritide in the Management of Acute Diastolic Heart Failure

Terminated

NCT00543309Phase 2

Effects of Perioperative Nesiritide or Milrinone Infusion on Recovery From Fontan Surgery

Terminated

NCT01544998Phase 1

Tadalafil and Nesiritide as Therapy in Pre-clinical Heart Failure

Completed

NCT01977859Phase 1

BNP Pharmacodynamics and Effects on Metabolism in Lean and Obese Subjects

Completed

NCT02608996Phase 1

Nesiritide in Hypertension

Recruiting

NCT02642523Early Phase 1

Natriuretic Peptides and Metabolic Risk in Obesity

Withdrawn

NCT00348556Phase 1

Use of Nesiritide (BNP) in Kidney Function in Patients With Congestive Heart Failure (CHF) and Kidney Failure

Terminated

NCT02269072Not Applicable

Testosterone Regulation of the Natriuretic Peptide System

Withdrawn

NCT03207295Not Applicable

Impact of Nesiritide on Early Postoperative Recovery After Total Cavo-Pulmonary Connection Surgery in Children

Unknown

NCT00530361Phase 3

An Efficacy and Safety Study for Nesiritide in Heart Failure Patients With Reduced Kidney Function Undergoing Coronary Artery Bypass Graft Surgery Requiring Cardiopulmonary Bypass (CPB Pump or Heart Lung Machine)

Withdrawn

NCT01836809Phase 4

Nesiritide and Renal Function After the Total Artificial Heart

Terminated

NCT00505791Phase 4

Double Blind Randomized Placebo Controlled Trial of Natrecor in Acute Decompensated Heart Failure With Normal EF

Withdrawn

NCT00562692Phase 3

Role of Natriuretic Peptides in the Treatment of Acutely Decompensated Heart Failure Patient With Obstructive Airways Disease

Terminated

NCT00453453Phase 4

BNP Therapy Observation Unit Outcomes STudy (BOOST)

Terminated

NCT00573144Phase 2

Nesiritide Therapy to Preserve Function of the Left Ventricle After Myocardial Infarction

Completed

NCT01132846Phase 2

Renal Optimization Strategies Evaluation in Acute Heart Failure and Reliable Evaluation of Dyspnea in the Heart Failure Network (ROSE) Study

Completed

Drug Details

Intervention Type: DRUG
Total Trials: 39