Neratinib
Neratinib is a pharmaceutical drug with 69 clinical trials. Currently 15 active trials ongoing. Historical success rate of 83.3%.
Success Metrics
Based on 35 completed trials
Phase Distribution
Phase Distribution
31
Early Stage
30
Mid Stage
3
Late Stage
Highest Phase Reached
Phase 3Trial Status & Enrollment
74.5%
35 of 47 finished
25.5%
12 ended early
15
trials recruiting
69
all time
Detailed Status
Development Timeline
Analytics
Development Status
Trials by Phase
Trials by Status
Recent Activity
T-DXd With or Without Neratinib for HER2 Positive Breast Cancer With Brain Metastasis
Trial of Pre-operative Neratinib and Endocrine Therapy With Trastuzumab in ER-Positive, HER-2 Positive Breast Cancers
Innovative Trial for Understanding the Impact of Targeted Therapies in NF2-Related Schwannomatosis (INTUITT-NF2)
INdividualized Screening Trial of Innovative Glioblastoma Therapy (INSIGhT)
Neoadjuvant Neratinib in Stage I-III HER2-Mutated Lobular Breast Cancers
Clinical Trials (69)
T-DXd With or Without Neratinib for HER2 Positive Breast Cancer With Brain Metastasis
Trial of Pre-operative Neratinib and Endocrine Therapy With Trastuzumab in ER-Positive, HER-2 Positive Breast Cancers
Innovative Trial for Understanding the Impact of Targeted Therapies in NF2-Related Schwannomatosis (INTUITT-NF2)
INdividualized Screening Trial of Innovative Glioblastoma Therapy (INSIGhT)
Neoadjuvant Neratinib in Stage I-III HER2-Mutated Lobular Breast Cancers
Neratinib and Everolimus, Palbociclib, or Trametinib in Treating Participants With Refractory and Advanced or Metastatic Solid Tumors With EGFR Mutation/Amplification, HER2 Mutation/Amplification, or HER3/4 Mutation or KRAS Mutation
Neratinib + Valproate in Advanced Solid Tumors, w/Expansion Cohort in Ras-Mutated Ca
Using Tumor Models to Determine Treatments
Neratinib In Combination With Chemotherapy/Trastuzumab/Pembrolizumab In HER2 Gastroesophageal Cancer
Personalized Medicine for Advanced Biliary Cancer Patients
I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer
Capecitabine 7/7 Schedule With Neratinib in Patients With Metastatic HER2-Positive Breast Cancer
Neratinib and Paclitaxel With or Without Pertuzumab and Trastuzumab Before Combination Chemotherapy in Treating Patients With Metastatic or Locally Advanced Breast Cancer
Neratinib +/- Fulvestrant in HER2+, ER+ Metastatic Breast Cancer
Genetically-informed Therapy for ER+ Breast Cancer Post-CDK4/6 Inhibitor
Safety and Dose Finding Study of Neratinib in Children and Young Adults With Cancer That Has Returned or Not Responded to Treatment
Real-life Pan-HER-blockade With Neratinib
Incidence and Severity of Diarrhea in Patients With HER2 Positive Breast Cancer Treated With Trastuzumab and Neratinib
Neratinib and Capmatinib Combination (Phase Ib/II) in Metastatic Breast Cancer and Inflammatory Breast Cancer Patients With Abnormal HER-family and c-Met Pathway Activity as Measured by the CELsignia Signaling Analysis Test
Three Antidiarrheal Strategies in HER2+/HR+ Early Breast Cancer Patients Treated With Extended Adjuvant Neratinib
Drug Details
- Intervention Type
- DRUG
- Total Trials
- 69