Success Metrics

Clinical Success Rate
75.0%

Based on 15 completed trials

Completion Rate
75%(15/20)
Active Trials
6(21%)
Results Posted
27%(4 trials)
Terminated
5(17%)

Phase Distribution

Ph phase_3
3
10%
Ph phase_1
5
17%
Ph phase_2
16
55%
Ph not_applicable
2
7%

Phase Distribution

5

Early Stage

16

Mid Stage

3

Late Stage

Phase Distribution26 total trials
Phase 1Safety & dosage
5(19.2%)
Phase 2Efficacy & side effects
16(61.5%)
Phase 3Large-scale testing
3(11.5%)
N/ANon-phased studies
2(7.7%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

71.4%

15 of 21 finished

Non-Completion Rate

28.6%

6 ended early

Currently Active

6

trials recruiting

Total Trials

29

all time

Status Distribution
Active(7)
Completed(15)
Terminated(6)
Other(1)

Detailed Status

Completed15
Terminated5
Active, not recruiting3
Recruiting3
unknown1
Not yet recruiting1

Development Timeline

Analytics

Development Status

Total Trials
29
Active
6
Success Rate
75.0%
Most Advanced
Phase 3

Trials by Phase

Phase 15 (19.2%)
Phase 216 (61.5%)
Phase 33 (11.5%)
N/A2 (7.7%)

Trials by Status

unknown13%
not_yet_recruiting13%
completed1552%
active_not_recruiting310%
terminated517%
withdrawn13%
recruiting310%

Recent Activity

Clinical Trials (29)

Showing 20 of 29 trialsScroll for more
NCT06390319Phase 2

Adding Dasatinib Or Venetoclax To Improve Responses In Children With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (ALL) Or Lymphoma (T-LLY) Or Mixed Phenotype Acute Leukemia (MPAL)

Recruiting
NCT07294677Phase 1

CApivasertib, Venetoclax And Low-intensity chemotheRapY for Adults With ALL/LBL

Recruiting
NCT03020030Phase 3

Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Children and Adolescents

Active Not Recruiting
NCT03808610Phase 1

Low-Intensity Chemotherapy and Venetoclax in Treating Patients With Relapsed or Refractory B- or T-Cell Acute Lymphoblastic Leukemia

Active Not Recruiting
NCT00501826Phase 2

Combination Chemotherapy and Nelarabine in Treating Patients With T-cell Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma

Recruiting
NCT07072585Phase 2

Testing the Addition of Daratumumab to Chemotherapy for Treating Patients With Newly-Diagnosed T-Cell Lymphoblastic Leukemia (T-ALL) and T-Cell Lymphoblastic Lymphoma (T-LL)

Not Yet Recruiting
NCT02881086Phase 3

Optimization of Therapy in Adult Patients With Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma by Individualised, Targeted and Intensified Treatment

Completed
NCT03117751Phase 2

Total Therapy XVII for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia and Lymphoma

Active Not Recruiting
NCT00408005Phase 3

Combination Chemotherapy in Treating Young Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or T-cell Lymphoblastic Lymphoma

Completed
NCT01085617

Standard Chemotherapy with or Without Nelarabine or Rituximab in Treating Patients with Newly Diagnosed Acute Lymphoblastic Leukemia

Completed
NCT06210750Phase 2

Adding Targeted Drugs to Usual Chemotherapy for Adults With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (T-ALL) and T-Cell Lymphoblastic Lymphoma (T-LBL)

Withdrawn
NCT02763384Phase 2

BL-8040 and Nelarabine for Relapsed or Refractory T-Acute Lymphoblastic Leukemia/ Lymphoblastic Lymphoma

Terminated
NCT03328104Phase 1

Everolimus in Combination With Nelarabine, Cyclophosphamide and Etoposide in Lymphoblastic Leukemia/Lymphoma

Completed
NCT00684619Phase 2

506U78 In Relapsed Or Refractory Acute Lymphoblastic Leukemia (T-ALL)

Completed
NCT00981799Phase 1

Trial of Nelarabine, Etoposide and Cyclophosphamide in Relapsed T-cell ALL and T-cell LL

Terminated
NCT01094860Phase 1

Pharmacokinetic (PK) and Pharmacodynamic (PD) Study of Nelarabine in Patients With Relapsed/Refractory Lymphoid Malignancies

Completed
NCT02619630Phase 2

Multicenter Study of Risk-adapted Treatment for T-lineage ALL of Young Adults (18-59 Years Old)

Unknown
NCT02518750Phase 2

Re-Induction Therapy for Relapsed Pediatric T-Cell Acute Lymphoblastic Leukemia or Lymphoma

Terminated
NCT01376115

Drug Use Investigation for ARRANON G (Nelarabine) Injection 250mg

Completed
NCT00006020Phase 2

S0010 506U78 in Treating Patients With Recurrent or Refractory Acute Lymphocytic Leukemia

Completed

Drug Details

Intervention Type
DRUG
Total Trials
29