Success Metrics

Clinical Success Rate
75.0%

Based on 6 completed trials

Completion Rate
75%(6/8)
Active Trials
3(25%)
Results Posted
100%(6 trials)
Terminated
2(17%)

Phase Distribution

Ph phase_1
7
58%
Ph early_phase_1
1
8%
Ph phase_2
4
33%

Phase Distribution

8

Early Stage

4

Mid Stage

0

Late Stage

Phase Distribution12 total trials
Early Phase 1First-in-human
1(8.3%)
Phase 1Safety & dosage
7(58.3%)
Phase 2Efficacy & side effects
4(33.3%)

Highest Phase Reached

Phase 2

Trial Status & Enrollment

Completion Rate

75.0%

6 of 8 finished

Non-Completion Rate

25.0%

2 ended early

Currently Active

3

trials recruiting

Total Trials

12

all time

Status Distribution
Active(3)
Completed(6)
Terminated(2)
Other(1)

Detailed Status

Completed6
Recruiting3
Terminated2
unknown1

Development Timeline

Analytics

Development Status

Total Trials
12
Active
3
Success Rate
75.0%
Most Advanced
Phase 2

Trials by Phase

Early Phase 11 (8.3%)
Phase 17 (58.3%)
Phase 24 (33.3%)

Trials by Status

completed650%
recruiting325%
terminated217%
unknown18%

Recent Activity

Clinical Trials (12)

Showing 12 of 12 trials
NCT07144384Early Phase 1

Intratumoral Injection of Standard Universal Donor Expanded Natural Killer Cells and TGF-beta Imprinted Natural Killer Cells for the Treatment of Skin Squamous Cell Carcinoma and Basal Cell Carcinoma

Recruiting
NCT04848064Phase 1

Third-Party Natural Killer Cells and Mogamulizumab for the Treatment of Relapsed or Refractory Cutaneous T-cell Lymphomas or Adult T-Cell Leukemia/Lymphoma

Recruiting
NCT05588453Phase 1

Natural Killer Cell Therapy (UD TGFbetai NK Cells) and Temozolomide for the Treatment of Stage IV Melanoma Metastatic to the Brain

Recruiting
NCT01729091Phase 2

Umbilical Cord Blood-Derived Natural Killer Cells, Elotuzumab, Lenalidomide, and High Dose Melphalan, Followed by Stem Cell Transplant in Treating Patients With Multiple Myeloma

Completed
NCT01904136Phase 1

Natural Killer Cells Before and After Donor Stem Cell Transplant in Treating Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelogenous Leukemia

Completed
NCT02271711Phase 1

Expanded Natural Killer Cell Infusion in Treating Younger Patients With Recurrent/Refractory Brain Tumors

Completed
NCT02316964Phase 1

Decitabine, Donor Natural Killer Cells, and Aldesleukin in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

Completed
NCT01619761Phase 1

NK Cells in Cord Blood Transplantation

Unknown
NCT00789776Phase 1

Fludarabine Phosphate, Cyclophosphamide, Total-Body Irradiation, and Donor Bone Marrow Transplant Followed by Donor Natural Killer Cell Therapy, Mycophenolate Mofetil, and Tacrolimus in Treating Patients With Hematologic Cancer

Completed
NCT02259348Phase 2

Repeat Transplantation for Relapsed or Refractory Hematologic Malignancies Following Prior Transplantation

Terminated
NCT00450983Phase 2

Donor Peripheral Stem Cell Transplant and Donor Natural Killer Cell Transplant After Total-Body Irradiation, Thiotepa, Fludarabine, and Muromonab-CD3 in Treating Patients With Leukemia or Other Blood Diseases

Terminated
NCT00526292Phase 2

Chemotherapy and a Donor Natural Killer Cell Infusion in Treating Patients With Relapsed or Persistent Leukemia or Myelodysplastic Syndrome After a Donor Stem Cell Transplant

Completed

All 12 trials loaded

Drug Details

Intervention Type
BIOLOGICAL
Total Trials
12