Success Metrics

Clinical Success Rate
78.8%

Based on 41 completed trials

Completion Rate
79%(41/52)
Active Trials
2(3%)
Results Posted
39%(16 trials)
Terminated
11(18%)

Phase Distribution

Ph not_applicable
1
2%
Ph phase_1
6
10%
Ph phase_2
14
23%
Ph phase_4
11
18%
Ph phase_3
10
17%

Phase Distribution

6

Early Stage

14

Mid Stage

21

Late Stage

Phase Distribution42 total trials
Phase 1Safety & dosage
6(14.3%)
Phase 2Efficacy & side effects
14(33.3%)
Phase 3Large-scale testing
10(23.8%)
Phase 4Post-market surveillance
11(26.2%)
N/ANon-phased studies
1(2.4%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

75.9%

41 of 54 finished

Non-Completion Rate

24.1%

13 ended early

Currently Active

2

trials recruiting

Total Trials

60

all time

Status Distribution
Active(2)
Completed(41)
Terminated(13)
Other(4)

Detailed Status

Completed41
Terminated11
unknown4
Withdrawn2
Recruiting1
Active, not recruiting1

Development Timeline

Analytics

Development Status

Total Trials
60
Active
2
Success Rate
78.8%
Most Advanced
Phase 4

Trials by Phase

Phase 16 (14.3%)
Phase 214 (33.3%)
Phase 310 (23.8%)
Phase 411 (26.2%)
N/A1 (2.4%)

Trials by Status

recruiting12%
withdrawn23%
completed4168%
terminated1118%
unknown47%
active_not_recruiting12%

Recent Activity

Clinical Trials (60)

Showing 20 of 60 trialsScroll for more
NCT05925049

A Study Utilising Data From European Union (EU) National Multiple Sclerosis (MS) Registries to Assess the Incidence of Anti-Natalizumab Antibody Among Participants Who Receive Subcutaneous Administration of Natalizumab for Treatment of Relapsing-remitting Multiple Sclerosis (RRMS)

Active Not Recruiting
NCT05265728Phase 3

A Study to Evaluate Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Multiple Doses of Natalizumab (BG00002) Administered Subcutaneously to Japanese Participants With Relapsing-Remitting Multiple Sclerosis

Terminated
NCT05688436

A Study to Learn More About The Safety of Diroximel Fumarate (VUMERITY®) in Participants Who Took it During Pregnancy And About the Health of Their Babies

Recruiting
NCT05618301Phase 1

Motixafortide and Natalizumab to Mobilize CD34+ Hematopoietic Stem Cells for Gene Therapies in Sickle Cell Disease (SCD)

Completed
NCT05236777

TOPIK Study: A Study to Report Progressive Multifocal Leukoencephalopathy and Other Serious Opportunistic Infections in Natalizumab Treated Participants

Completed
NCT03046251Phase 4

Natalizumab in Preventing Post-partum Relapses in Multiple Sclerosis

Completed
NCT03811886Phase 1

Natalizumab in Recurrent, Refractory or Progressive Pulmonary Metastatic Osteosarcoma

Withdrawn
NCT06705608

Examining the Risk of Skin Cancer in Multiple Sclerosis Patients Using Fingolimod: a Population-Based Study

Completed
NCT05701423

A Study of End of Dose Phenomena in Subcutaneous Natalizumab Treated Multiple Sclerosis (MS) Participants

Terminated
NCT05532163Phase 4

A Study to Investigate the Radiological Onset of Action After Treatment Initiation With Subcutaneous (SC) Natalizumab in Participants With Relapsing-Remitting Multiple Sclerosis (RRMS)

Terminated
NCT03689972Phase 3

A Study to Evaluate Efficacy, Safety, and Tolerability of EID of Natalizumab (BG00002) in Participants With RRMS Switching From Treatment With Natalizumab SID in Relation to Continued SID Treatment- Followed by Extension Study Comprising SC and IV Natalizumab Administration

Completed
NCT02142192Phase 2

Natalizumab Subcutaneous Immunogenicity and Safety Study

Terminated
NCT00707512

CD INFORM: Investigating Natalizumab Through Further Observational Research and Monitoring

Terminated
NCT05304520

A Study for Tysabri Participant Preference

Completed
NCT03093064Phase 1

Inflammatory Response In Schizophrenia

Completed
NCT04832399

Study of Tysabri in Early Relapsing Remitting Multiple Sclerosis Participants

Completed
NCT05627271

The 'Wearing Off' Effect of DMT

Completed
NCT02133924Phase 2

Multicenter Study Of Natalizumab Plus Standard Steroid Treatment For High Risk Acute Graft-Versus-Host Disease

Completed
NCT04964700

Analysis of MS Patients Who Have Had Greater Than 60 Infusions of Natalizumab

Unknown
NCT03283371Phase 2

Phase 2 Efficacy, Safety, and Tolerability Study of Natalizumab in Focal Epilepsy

Completed

Drug Details

Intervention Type
DRUG
Total Trials
60