Success Metrics

Clinical Success Rate
95.2%

Based on 20 completed trials

Completion Rate
95%(20/21)
Active Trials
3(10%)
Results Posted
60%(12 trials)
Terminated
1(3%)

Phase Distribution

Ph early_phase_1
2
6%
Ph phase_1
4
13%
Ph phase_4
2
6%
Ph phase_2
15
48%
Ph not_applicable
4
13%
Ph phase_3
4
13%

Phase Distribution

6

Early Stage

15

Mid Stage

6

Late Stage

Phase Distribution31 total trials
Early Phase 1First-in-human
2(6.5%)
Phase 1Safety & dosage
4(12.9%)
Phase 2Efficacy & side effects
15(48.4%)
Phase 3Large-scale testing
4(12.9%)
Phase 4Post-market surveillance
2(6.5%)
N/ANon-phased studies
4(12.9%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

95.2%

20 of 21 finished

Non-Completion Rate

4.8%

1 ended early

Currently Active

3

trials recruiting

Total Trials

31

all time

Status Distribution
Active(5)
Completed(20)
Terminated(1)
Other(5)

Detailed Status

Completed20
unknown5
Active, not recruiting3
Not yet recruiting2
Terminated1

Development Timeline

Analytics

Development Status

Total Trials
31
Active
3
Success Rate
95.2%
Most Advanced
Phase 4

Trials by Phase

Early Phase 12 (6.5%)
Phase 14 (12.9%)
Phase 215 (48.4%)
Phase 34 (12.9%)
Phase 42 (6.5%)
N/A4 (12.9%)

Trials by Status

terminated13%
unknown516%
active_not_recruiting310%
not_yet_recruiting26%
completed2065%

Recent Activity

Clinical Trials (31)

Showing 20 of 31 trialsScroll for more
NCT06311045Not Applicable

Obstructive Sleep Apnea (OSA) and Sex-Specific Responses to N-acetylcysteine (NAC)

Active Not Recruiting
NCT04481035Phase 2

Antioxidant Therapy With N-acetylcysteine for Learning and Motor Behavior in Children With Neurofibromatosis Type 1

Completed
NCT03493178Early Phase 1

Glutathione in Mild Cognitive Impairment

Active Not Recruiting
NCT04013555Phase 1

The Effects of Kynurenine Aminotransferase Inhibition in People With Schizophrenia

Completed
NCT07374991Not Applicable

Clinical and Molecular Effects of N-Acetylcysteine Treatment in COVID-19-Related Acute Respiratory Distress Syndrome

Completed
NCT07262554Phase 2

N-acetylcysteine for Root Canal Treatment of Necrotic Teeth With Apical Periodontitis

Active Not Recruiting
NCT07156786Phase 2

N-Acetylcysteine Roles in Preserving Renal Function Measured by Urinary KIM-1 (Kidney Injury Molecule-1) and Serum Creatinine on Cancer Patients With Cisplatin Based Chemotherapy: A Randomized Placebo-Controlled Trial

Not Yet Recruiting
NCT06890507Phase 2

The Anti-Anginal Effects of N-Acetylcysteine (NAC) in Patients with Angina and Non-Obstructive Coronary Arteries (ANOCA)

Not Yet Recruiting
NCT00780962Phase 2

N-Acetylcysteine to Prevent Radiocontrast Nephropathy in Emergency Department Patients

Completed
NCT03636932Phase 2

RENACTIF: Reduction of the Thrombotic Phenotype in Renal Insufficiency With N-AcetylCysteine

Completed
NCT02723162Phase 2

Translational Neuropsychopharmacology Research of Nicotine Addiction

Completed
NCT04928495Phase 3

Clinical Trial With N-acetylcysteine and Bromhexine for COVID-19

Unknown
NCT03881163Phase 1

A Study to Evaluate Pharmacokinetics, Safety and Tolerability of Single and Multiple Intravenous Doses of N-acetylcysteine (NAC) in Chinese Healthy Volunteers

Completed
NCT02737358Phase 2

N-acetylcysteine for Tobacco Use Disorder

Completed
NCT02269540Early Phase 1

A New Treatment Approach for Major Depressive Disorder Based Upon Targeting Monoamine Oxidase A (MAO-A)

Completed
NCT03708458Phase 4

Pharmacological Prophylaxis of Post- Endoscopic Retrograde Cholangiopancreatography (ERCP) Pancreatitis

Unknown
NCT01993849Phase 3

Use of N-Acetylcysteine (NAC) in Fingernail Biting

Completed
NCT01797575Phase 2

N-Acetyl Cysteine and Aspirin as an Adjunctive Treatment for Bipolar Disorder

Completed
NCT00004467Phase 3

Randomized Study of Acetylcysteine in Patients With Acute Liver Failure Not Caused by Acetaminophen

Completed
NCT03197103Phase 4

The Impact of N-Acetylcysteine on Volumetric Retention of Autologous Fat Graft for Breast Asymmetry Correction

Unknown

Drug Details

Intervention Type
DIETARY SUPPLEMENT
Total Trials
31