Success Metrics

Clinical Success Rate
50.0%

Based on 5 completed trials

Completion Rate
50%(5/10)
Active Trials
125(81%)
Results Posted
440%(22 trials)
Terminated
5(3%)

Phase Distribution

Ph phase_1
71
46%
Ph phase_3
14
9%
Ph phase_2
69
45%
Ph early_phase_1
1
1%

Phase Distribution

72

Early Stage

69

Mid Stage

14

Late Stage

Phase Distribution155 total trials
Early Phase 1First-in-human
1(0.6%)
Phase 1Safety & dosage
71(45.8%)
Phase 2Efficacy & side effects
69(44.5%)
Phase 3Large-scale testing
14(9.0%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

33.3%

5 of 15 finished

Non-Completion Rate

66.7%

10 ended early

Currently Active

125

trials recruiting

Total Trials

155

all time

Status Distribution
Active(136)
Completed(5)
Terminated(10)
Other(4)

Detailed Status

Recruiting79
Active, not recruiting46
Not yet recruiting11
Terminated5
Withdrawn5
Completed5

Development Timeline

Analytics

Development Status

Total Trials
155
Active
125
Success Rate
50.0%
Most Advanced
Phase 3

Trials by Phase

Early Phase 11 (0.6%)
Phase 171 (45.8%)
Phase 269 (44.5%)
Phase 314 (9.0%)

Trials by Status

active_not_recruiting4630%
suspended43%
terminated53%
not_yet_recruiting117%
recruiting7951%
withdrawn53%
completed53%

Recent Activity

Clinical Trials (155)

Showing 20 of 155 trialsScroll for more
NCT06863402Phase 2

Nemtabrutinib and Pembrolizumab for the Treatment of Richter Transformation, Diffuse Large B-cell Lymphoma Subtype

Recruiting
NCT05372614Phase 1

Testing the Safety and Tolerability of the Anti-cancer Drugs Trastuzumab Deruxtecan and Neratinib for Cancers With Changes in the HER2 Gene

Recruiting
NCT06124157Phase 2

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

Recruiting
NCT06172296Phase 3

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

Recruiting
NCT06876714Phase 3

ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab

Recruiting
NCT05564377Phase 2

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

Recruiting
NCT05256225Phase 3

Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

Active Not Recruiting
NCT04231877Phase 1

Polatuzumab Vedotin and Combination Chemotherapy With or Without Glofitamab for the Treatment of Untreated Aggressive Large B-cell Lymphoma

Active Not Recruiting
NCT05828069Phase 2

A Study With Tovorafenib (DAY101) as a Treatment Option for Progressive, Relapsed, or Refractory Langerhans Cell Histiocytosis

Recruiting
NCT04799275Phase 2

Testing CC-486 (Oral Azacitidine) Plus the Standard Drug Therapy in Patients 75 Years or Older With Newly Diagnosed Diffuse Large B Cell Lymphoma

Active Not Recruiting
NCT05554419Phase 2

Testing the Use of Combination Therapy in Patients With Persistent Low Level Acute Myeloid Leukemia Following Initial Treatment, The ERASE Study (A MyeloMATCH Treatment Trial)

Not Yet Recruiting
NCT03660826Phase 2

Testing the Combination of Olaparib and Durvalumab, Cediranib and Durvalumab, Olaparib and Capivasertib, and Cediranib Alone in Recurrent or Refractory Endometrial Cancer Following the Earlier Phase of the Study That Tested Olaparib and Cediranib in Comparison to Cediranib Alone, and Olaparib Alone

Active Not Recruiting
NCT07301268Phase 2

GI-102 Alone or With Pembrolizumab Before Surgery for Treatment of Recurrent or Progressive IDH Wildtype Glioblastoma and IDH Mutated Grade 4 Astrocytoma

Recruiting
NCT04739800Phase 2

Comparison of Standard of Care Treatment With a Triplet Combination of Targeted Immunotherapeutic Agents

Active Not Recruiting
NCT06126276Phase 2

Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)

Recruiting
NCT04181060Phase 3

Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

Recruiting
NCT05432791Phase 2

Testing Olaparib and Temozolomide Versus the Usual Treatment for Uterine Leiomyosarcoma After Chemotherapy Has Stopped Working

Active Not Recruiting
NCT02224781Phase 3

Dabrafenib and Trametinib Followed by Ipilimumab and Nivolumab or Ipilimumab and Nivolumab Followed by Dabrafenib and Trametinib in Treating Patients With Stage III-IV BRAFV600 Melanoma

Active Not Recruiting
NCT06484062Phase 1

Testing the Anti-cancer Drug, Cirtuvivint, and Its Combination With ASTX727 to Improve Outcomes in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndromes

Recruiting
NCT02446600Phase 3

Testing the Use of A Single Drug (Olaparib) or the Combination of Two Drugs (Cediranib and Olaparib) Compared to the Usual Chemotherapy for Women With Platinum Sensitive Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Active Not Recruiting

Drug Details

Intervention Type
PROCEDURE
Total Trials
155