Success Metrics

Clinical Success Rate
50.0%

Based on 4 completed trials

Completion Rate
50%(4/8)
Active Trials
122(81%)
Results Posted
525%(21 trials)
Terminated
4(3%)

Phase Distribution

Ph early_phase_1
1
1%
Ph phase_3
13
9%
Ph phase_2
67
45%
Ph phase_1
69
46%

Phase Distribution

70

Early Stage

67

Mid Stage

13

Late Stage

Phase Distribution150 total trials
Early Phase 1First-in-human
1(0.7%)
Phase 1Safety & dosage
69(46.0%)
Phase 2Efficacy & side effects
67(44.7%)
Phase 3Large-scale testing
13(8.7%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

30.8%

4 of 13 finished

Non-Completion Rate

69.2%

9 ended early

Currently Active

122

trials recruiting

Total Trials

150

all time

Status Distribution
Active(132)
Completed(4)
Terminated(9)
Other(5)

Detailed Status

Recruiting78
Active, not recruiting44
Not yet recruiting10
Suspended5
Withdrawn5
Completed4

Development Timeline

Analytics

Development Status

Total Trials
150
Active
122
Success Rate
50.0%
Most Advanced
Phase 3

Trials by Phase

Early Phase 11 (0.7%)
Phase 169 (46.0%)
Phase 267 (44.7%)
Phase 313 (8.7%)

Trials by Status

suspended53%
recruiting7852%
completed43%
not_yet_recruiting107%
terminated43%
withdrawn53%
active_not_recruiting4429%

Recent Activity

Clinical Trials (150)

Showing 20 of 150 trialsScroll for more
NCT05554393Phase 2

Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)

Recruiting
NCT02224781Phase 3

Dabrafenib and Trametinib Followed by Ipilimumab and Nivolumab or Ipilimumab and Nivolumab Followed by Dabrafenib and Trametinib in Treating Patients With Stage III-IV BRAFV600 Melanoma

Active Not Recruiting
NCT02465060Phase 2

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

Active Not Recruiting
NCT06422806Phase 3

Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas

Recruiting
NCT05564390Phase 2

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Recruiting
NCT05256225Phase 3

Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

Recruiting
NCT05554406Phase 2

Testing New Therapies for Patients With Acute Myeloid Leukemia Who Are Newly Diagnosed and Have Not Yet Started Treatment (A MyeloMATCH Treatment Trial)

Recruiting
NCT02339571Phase 2

A Phase II/III Trial of Nivolumab, Ipilimumab, and GM-CSF in Patients With Advanced Melanoma

Active Not Recruiting
NCT04616560Phase 1

Trastuzumab Deruxtecan (DS-8201a) for the Treatment of Recurrent or Refractory Osteosarcoma, Wilms Tumor, and Desmoplastic Small Round Cell Tumor

Recruiting
NCT05564377Phase 2

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

Recruiting
NCT03191149Phase 2

Testing Osimertinib as a Treatment for Lung Cancers With an EGFR Exon 20 Change

Recruiting
NCT05554328Phase 2

Testing the Use of the Combination of Selumetinib and Olaparib or Selumetinib Alone Targeted Treatment for RAS Pathway Mutant Recurrent or Persistent Ovarian and Endometrial Cancers, A ComboMATCH Treatment Trial

Active Not Recruiting
NCT04181060Phase 3

Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

Recruiting
NCT06126276Phase 2

Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)

Recruiting
NCT02196181Phase 2

Testing Two Different Treatment Schedules of Dabrafenib and Trametinib for Skin Cancer Which Has Spread

Active Not Recruiting
NCT04739800Phase 2

Comparison of Standard of Care Treatment With a Triplet Combination of Targeted Immunotherapeutic Agents

Active Not Recruiting
NCT05564403Phase 2

Study of Chemotherapy, With or Without Binimetinib in Advanced Biliary Tract Cancers in 2nd Line Setting (A ComboMATCH Treatment Trial)

Active Not Recruiting
NCT04284787Phase 2

BLAST MRD AML-2: BLockade of PD-1 Added to Standard Therapy to Target Measurable Residual Disease in Acute Myeloid Leukemia 2- A Randomized Phase 2 Study of Anti-PD-1 Pembrolizumab in Combination With Azacitidine and Venetoclax as Frontline Therapy in Unfit Patients With Acute Myeloid Leukemia

Active Not Recruiting
NCT06102902Phase 1

Testing the Addition of Anti-cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment, Cetuximab Plus Encorafenib, for Colorectal Cancer

Suspended
NCT05432791Phase 2

Testing Olaparib and Temozolomide Versus the Usual Treatment for Uterine Leiomyosarcoma After Chemotherapy Has Stopped Working

Active Not Recruiting

Drug Details

Intervention Type
PROCEDURE
Total Trials
150