Success Metrics

Clinical Success Rate

84.9%

Based on 79 completed trials

Completion Rate

85%(79/93)

Active Trials

7(6%)

Results Posted

44%(35 trials)

Terminated

14(12%)

Phase Distribution

Ph early_phase_1

Ph phase_2

29%

Ph not_applicable

12%

Ph phase_1

20%

Ph phase_3

19%

Ph phase_4

15%

Phase Distribution

Early Stage

Mid Stage

Late Stage

Phase Distribution117 total trials

Early Phase 1First-in-human

4(3.4%)

Phase 1Safety & dosage

24(20.5%)

Phase 2Efficacy & side effects

34(29.1%)

Phase 3Large-scale testing

23(19.7%)

Phase 4Post-market surveillance

18(15.4%)

N/ANon-phased studies

14(12.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

80.6%

79 of 98 finished

Non-Completion Rate

19.4%

19 ended early

Currently Active

trials recruiting

Total Trials

119

all time

Status Distribution

Active(10)

Completed(79)

Terminated(19)

Other(11)

Detailed Status

Completed79

Terminated14

unknown11

Withdrawn5

Recruiting4

Active, not recruiting3

Development Timeline

Analytics

Development Status

Total Trials

119

Active

Success Rate

84.9%

Most Advanced

Phase 4

Trials by Phase

Early Phase 14 (3.4%)

Phase 124 (20.5%)

Phase 234 (29.1%)

Phase 323 (19.7%)

Phase 418 (15.4%)

N/A14 (12.0%)

Trials by Status

terminated1412%

recruiting43%

active_not_recruiting33%

unknown119%

withdrawn54%

not_yet_recruiting33%

completed7966%

Recent Activity

7 active trials

Showing 5 of 119

not_yet_recruitingphase_3

Clinical Trials (119)

Showing 20 of 119 trialsScroll for more

NCT07263022Phase 3

Cognitive Strategies in Early Psychosis 2

Not Yet Recruiting

NCT07231497Phase 3

Cognitive Strategies in Early Psychosis 1

Recruiting

NCT06404099Phase 2

RECOVER-SLEEP: Platform Protocol, Appendix_A (Hypersomnia)

Active Not Recruiting

NCT06404086Phase 2

RECOVER-SLEEP: Platform Protocol

Completed

NCT01988883Early Phase 1

Modafinil and Cognitive Function in POTS

Active Not Recruiting

NCT05333250Phase 1

Modafinil to Improve Fatiguability

Recruiting

NCT07295834Phase 2

Modafinil For Fatigue in IBD: A Feasibility Randomised Controlled Trial

Not Yet Recruiting

NCT06041048Phase 4

Investigation of Locus Coeruleus Function in Sustained Attention

Recruiting

NCT00262470Phase 1

Treatment of Orthostatic Intolerance

Active Not Recruiting

NCT07128719Not Applicable

Study Effects of Preoperative Modafinil on Recovery Profile of Morbidly Obese Patients Scheduled for Bariatric Surgery if it Can Enhance Recovery From Anesthesia

Completed

NCT06665230Phase 1

A Clinical Study of MK-6552 and Modafinil in Healthy Men (MK-6552-005)

Completed

NCT06619665Phase 1

A Study of MK-6552 in Sleep Deprived Healthy Participants (MK-6552-003)

Completed

NCT03864042Phase 1

Pharmacokinetic Drug-drug Interaction Study of Encorafenib and Binimetinib on Probe Drugs in Patients With BRAF V600-mutant Melanoma or Other Advanced Solid Tumors

Completed

NCT03772314Phase 2

Modafinil Versus Amphetamines for the Treatment of Narcolepsy Type 2 and Idiopathic Hypersomnia

Completed

NCT00439049

Substance Abuse Pre-Treatment Screening Study

Recruiting

NCT05675098Early Phase 1

Central Nervous System Stimulants and Physical Function in Children With Cerebral Palsy

Not Yet Recruiting

NCT02896712Phase 2

Developing Adaptive Interventions for Cocaine Cessation and Relapse Prevention