Success Metrics

Clinical Success Rate
85.1%

Based on 80 completed trials

Completion Rate
85%(80/94)
Active Trials
6(5%)
Results Posted
44%(35 trials)
Terminated
14(12%)

Phase Distribution

Ph phase_1
24
20%
Ph phase_3
23
19%
Ph phase_2
35
29%
Ph phase_4
18
15%
Ph not_applicable
15
12%
Ph early_phase_1
4
3%

Phase Distribution

28

Early Stage

35

Mid Stage

41

Late Stage

Phase Distribution119 total trials
Early Phase 1First-in-human
4(3.4%)
Phase 1Safety & dosage
24(20.2%)
Phase 2Efficacy & side effects
35(29.4%)
Phase 3Large-scale testing
23(19.3%)
Phase 4Post-market surveillance
18(15.1%)
N/ANon-phased studies
15(12.6%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

80.8%

80 of 99 finished

Non-Completion Rate

19.2%

19 ended early

Currently Active

6

trials recruiting

Total Trials

121

all time

Status Distribution
Active(11)
Completed(80)
Terminated(19)
Other(11)

Detailed Status

Completed80
Terminated14
unknown11
Withdrawn5
Not yet recruiting4
Recruiting4

Development Timeline

Analytics

Development Status

Total Trials
121
Active
6
Success Rate
85.1%
Most Advanced
Phase 4

Trials by Phase

Early Phase 14 (3.4%)
Phase 124 (20.2%)
Phase 235 (29.4%)
Phase 323 (19.3%)
Phase 418 (15.1%)
N/A15 (12.6%)

Trials by Status

not_yet_recruiting43%
enrolling_by_invitation11%
withdrawn54%
completed8066%
terminated1412%
recruiting43%
active_not_recruiting22%
unknown119%

Recent Activity

Clinical Trials (121)

Showing 20 of 121 trialsScroll for more
NCT06404099Phase 2

RECOVER-SLEEP: Platform Protocol, Appendix_A (Hypersomnia)

Completed
NCT07263022Phase 3

Cognitive Strategies in Early Psychosis 2

Not Yet Recruiting
NCT07582458Phase 2

Modafinil for Debilitating Fatigue in Quiescent Inflammatory Bowel Disease MODIFI-IBD Trial)

Not Yet Recruiting
NCT00916253Not Applicable

Method of Assessment of Driving Ability in Patients Suffering From Wakefulness Pathologies

Completed
NCT07568574Not Applicable

Impact of Medically Supervised Performance-Enhancing Substances (PES) on Elite Athletes

Enrolling By Invitation
NCT07231497Phase 3

Cognitive Strategies in Early Psychosis 1

Recruiting
NCT06404086Phase 2

RECOVER-SLEEP: Platform Protocol

Completed
NCT01988883Early Phase 1

Modafinil and Cognitive Function in POTS

Active Not Recruiting
NCT05333250Phase 1

Modafinil to Improve Fatiguability

Recruiting
NCT07295834Phase 2

Modafinil For Fatigue in IBD: A Feasibility Randomised Controlled Trial

Not Yet Recruiting
NCT06041048Phase 4

Investigation of Locus Coeruleus Function in Sustained Attention

Recruiting
NCT00262470Phase 1

Treatment of Orthostatic Intolerance

Active Not Recruiting
NCT07128719Not Applicable

Study Effects of Preoperative Modafinil on Recovery Profile of Morbidly Obese Patients Scheduled for Bariatric Surgery if it Can Enhance Recovery From Anesthesia

Completed
NCT06665230Phase 1

A Clinical Study of MK-6552 and Modafinil in Healthy Men (MK-6552-005)

Completed
NCT06619665Phase 1

A Study of MK-6552 in Sleep Deprived Healthy Participants (MK-6552-003)

Completed
NCT03864042Phase 1

Pharmacokinetic Drug-drug Interaction Study of Encorafenib and Binimetinib on Probe Drugs in Patients With BRAF V600-mutant Melanoma or Other Advanced Solid Tumors

Completed
NCT03772314Phase 2

Modafinil Versus Amphetamines for the Treatment of Narcolepsy Type 2 and Idiopathic Hypersomnia

Completed
NCT00439049

Substance Abuse Pre-Treatment Screening Study

Recruiting
NCT05675098Early Phase 1

Central Nervous System Stimulants and Physical Function in Children With Cerebral Palsy

Not Yet Recruiting
NCT02896712Phase 2

Developing Adaptive Interventions for Cocaine Cessation and Relapse Prevention

Completed

Drug Details

Intervention Type
DRUG
Total Trials
121