Success Metrics

Clinical Success Rate
100.0%

Based on 11 completed trials

Completion Rate
100%(11/11)
Active Trials
0(0%)
Results Posted
18%(2 trials)

Phase Distribution

Ph phase_3
1
8%
Ph phase_2
2
15%
Ph phase_1
10
77%

Phase Distribution

10

Early Stage

2

Mid Stage

1

Late Stage

Phase Distribution13 total trials
Phase 1Safety & dosage
10(76.9%)
Phase 2Efficacy & side effects
2(15.4%)
Phase 3Large-scale testing
1(7.7%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

84.6%

11 of 13 finished

Non-Completion Rate

15.4%

2 ended early

Currently Active

0

trials recruiting

Total Trials

13

all time

Status Distribution
Completed(11)
Terminated(2)

Detailed Status

Completed11
Withdrawn2

Development Timeline

Analytics

Development Status

Total Trials
13
Active
0
Success Rate
100.0%
Most Advanced
Phase 3

Trials by Phase

Phase 110 (76.9%)
Phase 22 (15.4%)
Phase 31 (7.7%)

Trials by Status

completed1185%
withdrawn215%

Recent Activity

Clinical Trials (13)

Showing 13 of 13 trials
NCT00605644Phase 2

Study Evaluating MOA-728 Oral for the Treatment of OIBD in Subjects With Chronic Non-Malignant Pain

Completed
NCT00427258Phase 1

Study Evaluating MOA-728 Administered in Healthy Men

Withdrawn
NCT00505583Phase 1

Study Evaluating Oral MOA-728 in Subjects on Methadone Therapy

Withdrawn
NCT00398502Phase 1

Comparisons Of The Bioavailability And Pharmacodynamics Of Various Formulations Of MOA-728 In Subjects On Methadone

Completed
NCT00366431Phase 2

Study Evaluating Oral MOA-728 for the Treatment of Opioid-Induced Bowel Dysfunction (OIBD) in Subjects With Chronic Non-Malignant Pain

Completed
NCT00387491Phase 1

Dose Ranging Study in Healthy Methadone Maintenance Subjects

Completed
NCT00447811Phase 1

Study Evaluating MOA-728 in Subjects on Stable Methadone Maintenance

Completed
NCT00464802Phase 1

Study Evaluating the Safety and Tolerability of a New Intravenous Formulation of MOA-728 in Healthy Subjects

Completed
NCT00387985Phase 1

Bioequivalence Study in Healthy Volunteers

Completed
NCT00311350Phase 1

Study Evaluating the Safety of MOA-728 Administered Orally to Healthy Subjects

Completed
NCT00434395Phase 1

Study Evaluating the Effects of MOA-728 on Cardiac Repolarization in Healthy Subjects

Completed
NCT00444158Phase 1

Double-Blind, Double-Dummy, 2-Period Crossover of a 20-Minute Versus a 4-hour IV of MOA-728 in Stable Methadone Subjects

Completed
NCT00528970Phase 3

A Study Evaluating Intravenous (IV) MOA-728 for the Treatment of Postoperative Ileus (POI) in Participants After Ventral Hernia Repair

Completed

All 13 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
13