Success Metrics

Clinical Success Rate
84.6%

Based on 11 completed trials

Completion Rate
85%(11/13)
Active Trials
0(0%)
Results Posted
55%(6 trials)
Terminated
2(13%)

Phase Distribution

Ph phase_3
1
7%
Ph phase_1
7
47%
Ph phase_2
7
47%

Phase Distribution

7

Early Stage

7

Mid Stage

1

Late Stage

Phase Distribution15 total trials
Phase 1Safety & dosage
7(46.7%)
Phase 2Efficacy & side effects
7(46.7%)
Phase 3Large-scale testing
1(6.7%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

73.3%

11 of 15 finished

Non-Completion Rate

26.7%

4 ended early

Currently Active

0

trials recruiting

Total Trials

15

all time

Status Distribution
Completed(11)
Terminated(4)

Detailed Status

Completed11
Terminated2
Withdrawn2

Development Timeline

Analytics

Development Status

Total Trials
15
Active
0
Success Rate
84.6%
Most Advanced
Phase 3

Trials by Phase

Phase 17 (46.7%)
Phase 27 (46.7%)
Phase 31 (6.7%)

Trials by Status

terminated213%
completed1173%
withdrawn213%

Recent Activity

Clinical Trials (15)

Showing 15 of 15 trials
NCT03731832Phase 2

Pomalidomide, Ixazomib, and Dexamethasone With or Without Intensification by Cyclophosphamide in Relapsed or Refractory Multiple Myeloma

Completed
NCT02586038Phase 2

STUDY THAT COMPARE 3 ARM: MLN9708 DEXAMETHASONE, MLN9708 CYCLOPHOSPHAMIDE AND DEXAMETHASONE, MLN9708 THALIDOMIDE AND DEXAMETHASONE FOLLOWED BY MAINTENANCE WITH MLN9708 IN NEWLY DIAGNOSED ELDERLY MULTIPLE MYELOMA PATIENTS

Completed
NCT01936532Phase 2

Safety and Efficacy Study of a Triplet Combination of MLN9708, Lenalidomide and Dexamethasone in the Initial Management of Multiple Myeloma (IFM2013-06)

Completed
NCT02582359Phase 1

MLN 9708 in Induction and Consolidation for Adults With AML >= 60 Years of Age

Completed
NCT02042989Phase 1

MLN9708 and Vorinostat in Patients With Advanced p53 Mutant Malignancies

Completed
NCT02169791Phase 2

Nonmyeloablative Haploidentical Transplant Followed by MLN9708

Completed
NCT02477215Phase 1

Study of Bendamustine and IXAZOMIB (MLN9708) Plus Dexamethasone in Relapsed/Refractory Multiple Myeloma

Completed
NCT02168101Phase 2

Determining the Feasibility of MLN9708 as Maintenance After Allogeneic Stem Cell Transplant for Multiple Myeloma

Completed
NCT01887587Phase 1

Vincristine, Doxorubicin, And Dexamethasone + Ixazomib in Acute Lymphoblastic Leukemia (ALL), Lymphoblastic Lymphoma Or Mixed Phenotype Acute Leukemia

Terminated
NCT01660997Phase 2

MLN9708 and Dexamethasone for High-Risk Smoldering Multiple Myeloma

Withdrawn
NCT02057640Phase 1

MLN9708 (Ixazomib) in Combination With Panobinostat and Dexamethasone in Multiple Myeloma

Completed
NCT02384746Phase 1

Phase I Study of the Combination of MLN9708 and Fulvestrant

Terminated
NCT03422874Phase 1

Dose Escalation Study of Nelfinavir Plus MLN9708 in Patients With Advanced Solid Tumors or Lymphoma

Withdrawn
NCT02406144Phase 3

Trial Studying Maintenance Treatment With Lenalidomide and Dexamethasone Versus Lenalidomide, Dexamethasone and MLN9708 After Autologous Hematopoietic Stem Cell Transplantation in Patients With Newly-diagnosed Symptomatic Multiple Myeloma

Completed
NCT02158975Phase 2

Open-label, Phase II Study of MLN9708 in Patients With Relapsed/Refractory Cutaneous and Peripheral T-cell Lymphomas

Completed

All 15 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
15