Success Metrics

Clinical Success Rate
69.2%

Based on 9 completed trials

Completion Rate
69%(9/13)
Active Trials
0(0%)
Results Posted
111%(10 trials)
Terminated
4(25%)

Phase Distribution

Ph phase_1
8
50%
Ph phase_2
8
50%

Phase Distribution

8

Early Stage

8

Mid Stage

0

Late Stage

Phase Distribution16 total trials
Phase 1Safety & dosage
8(50.0%)
Phase 2Efficacy & side effects
8(50.0%)

Highest Phase Reached

Phase 2

Trial Status & Enrollment

Completion Rate

60.0%

9 of 15 finished

Non-Completion Rate

40.0%

6 ended early

Currently Active

0

trials recruiting

Total Trials

16

all time

Status Distribution
Completed(9)
Terminated(6)
Other(1)

Detailed Status

Completed9
Terminated4
Withdrawn2
unknown1

Development Timeline

Analytics

Development Status

Total Trials
16
Active
0
Success Rate
69.2%
Most Advanced
Phase 2

Trials by Phase

Phase 18 (50.0%)
Phase 28 (50.0%)

Trials by Status

withdrawn213%
terminated425%
completed956%
unknown16%

Recent Activity

Clinical Trials (16)

Showing 16 of 16 trials
NCT01306045Phase 2

Molecular Profiling and Targeted Therapy for Advanced Non-Small Cell Lung Cancer, Small Cell Lung Cancer, and Thymic Malignancies

Completed
NCT00963547Phase 1

A Study of MK-2206 in Combination With Trastuzumab and Lapatinib for the Treatment of HER2+ Solid Tumors (MK-2206-015)

Terminated
NCT01248247Phase 2

BATTLE-2 Program: A Biomarker-Integrated Targeted Therapy Study in Previously Treated Patients With Advanced Non-Small Cell Lung Cancer

Completed
NCT00848718Phase 1

A Phase I Study of MK-2206 in Combination With Standard Chemotherapy in Participants With Locally Advanced or Metastatic Solid Tumors (MK-2206-003)

Completed
NCT00670488Phase 1

Dose Escalation Study With MK-2206 in Patients With Locally Advanced or Metastatic Solid Tumors (MK-2206-002)

Completed
NCT01243762Phase 1

A Study of Dalotuzumab + MK-2206, Dalotuzumab + MK-0752, and Dalotuzumab + Ridaforolimus Combination Therapies in Participants With Advanced Cancer (MK-0646-027)

Terminated
NCT01021748Phase 1

A Combination Therapy Study of MK-2206 and AZD6244 in Participants With Advanced Solid Tumors (MK-2206-010)

Completed
NCT01370070Phase 2

MK-2206 in Recurrent Nasopharyngeal Carcinoma

Completed
NCT01249105Phase 2

MK-2206 for Recurrent Malignant Glioma

Withdrawn
NCT01169649Phase 2

Study of MK-2206 in Patients With Metastatic Neuroendocrine Tumors (NET)

Completed
NCT01186705Phase 2

Clinical And Translational Study Of MK-2206 In Patients With Metastatic KRAS-Wild-Type, PIK3CA-Mutated, Colorectal Cancer

Terminated
NCT01295632Phase 1

Safety and Tolerability of Different Dose Combinations of Ridaforolimus With MK-2206 or MK-0752 for Participants With Advanced Cancer (MK-8669-049)

Completed
NCT01466868Phase 2

Study of MK 2206 in Patients With Relapsed or Refractory Diffuse Large B Cell Lymphoma

Terminated
NCT01235897Phase 1

MK-2206, Paclitaxel and Trastuzumab in Treating Patients With HER2-overexpressing Solid Tumor Malignancies

Completed
NCT01240941Phase 2

Trial of MK-2206 + Endocrine Treatment in Patients With Hormone Receptor Positive Breast Cancer

Withdrawn
NCT01147211Phase 1

Dose Defining Study For MK-2206 Combined With Gefitinib In Non Small Cell Lung Cancer (NSCLC)

Unknown

All 16 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
16