Success Metrics

Clinical Success Rate
64.9%

Based on 50 completed trials

Completion Rate
65%(50/77)
Active Trials
14(14%)
Results Posted
74%(37 trials)
Terminated
27(28%)

Phase Distribution

Ph phase_4
8
8%
Ph not_applicable
1
1%
Ph phase_2
42
43%
Ph phase_3
16
16%
Ph phase_1
30
31%

Phase Distribution

30

Early Stage

42

Mid Stage

24

Late Stage

Phase Distribution97 total trials
Phase 1Safety & dosage
30(30.9%)
Phase 2Efficacy & side effects
42(43.3%)
Phase 3Large-scale testing
16(16.5%)
Phase 4Post-market surveillance
8(8.2%)
N/ANon-phased studies
1(1.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

63.3%

50 of 79 finished

Non-Completion Rate

36.7%

29 ended early

Currently Active

14

trials recruiting

Total Trials

98

all time

Status Distribution
Active(14)
Completed(50)
Terminated(29)
Other(5)

Detailed Status

Completed50
Terminated27
Recruiting7
Active, not recruiting7
unknown5
Withdrawn2

Development Timeline

Analytics

Development Status

Total Trials
98
Active
14
Success Rate
64.9%
Most Advanced
Phase 4

Trials by Phase

Phase 130 (30.9%)
Phase 242 (43.3%)
Phase 316 (16.5%)
Phase 48 (8.2%)
N/A1 (1.0%)

Trials by Status

completed5051%
recruiting77%
unknown55%
active_not_recruiting77%
withdrawn22%
terminated2728%

Recent Activity

Clinical Trials (98)

Showing 20 of 98 trialsScroll for more
NCT03182244Phase 3

A Study of ASP2215 Versus Salvage Chemotherapy In Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) With FMS-like Tyrosine Kinase 3 (FLT3) Mutation

Active Not Recruiting
NCT02101853Phase 3

Blinatumomab in Treating Younger Patients With Relapsed B-cell Acute Lymphoblastic Leukemia

Active Not Recruiting
NCT03591510Phase 2

A Global Study of Midostaurin in Combination With Chemotherapy to Evaluate Safety, Efficacy and Pharmacokinetics in Newly Diagnosed Pediatric Patients With FLT3 Mutated AML

Active Not Recruiting
NCT03164057Phase 2

A Trial of Epigenetic Priming in Patients With Newly Diagnosed Acute Myeloid Leukemia

Active Not Recruiting
NCT05848687Phase 1

TINI 2: Total Therapy for Infants With Acute Lymphoblastic Leukemia II

Recruiting
NCT04797767Phase 1

Venetoclax and CLAG-M for the Treatment of Acute Myeloid Leukemia and High-Grade Myeloid Neoplasms

Recruiting
NCT03250338Phase 3

Study Investigating the Efficacy of Crenolanib With Chemotherapy vs Chemotherapy Alone in R/R FLT3 Mutated AML

Completed
NCT04375631Phase 1

CLAG-M or FLAG-Ida Chemotherapy and Reduced-Intensity Conditioning Donor Stem Cell Transplant for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelomonocytic Leukemia

Recruiting
NCT02523976Phase 2

Dasatinib Combined With Chemotherapy in Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia

Completed
NCT03926624Phase 3

Trial of DFP-10917 vs Non-Intensive or Intensive Reinduction for AML Patients in 2nd/3rd/4th Salvage

Terminated
NCT06429449Phase 1

Mitoxantrone for Venetoclax Resistant Acute Myeloid Leukemia

Recruiting
NCT02553460Phase 1

Total Therapy for Infants With Acute Lymphoblastic Leukemia (ALL) I

Active Not Recruiting
NCT03118466Phase 2

Mitoxantrone, Etoposide, and Cytarabine (MEC) Plus Lenalidomide for Relapsed or Refractory Acute Myeloid Leukemia

Completed
NCT03860844Phase 2

Isatuximab in Combination With Chemotherapy in Pediatric Patients With Relapsed/Refractory Acute Lymphoblastic Leukemia or Acute Myeloid Leukemia

Terminated
NCT06262438Phase 2

CHIP-AML22/Quizartinib: Quizartinib + Chemotherapy in Newly Diagnosed Pediatric FLT3-ITD+ and NPM1wt AML Patients

Recruiting
NCT04195945Phase 2

CPX-351 or CLAG-M Regimen for the Treatment of Acute Myeloid Leukemia or Other High-Grade Myeloid Neoplasms in Medically Less-Fit Patients

Active Not Recruiting
NCT02303821Phase 1

Study of Carfilzomib in Combination With Induction Chemotherapy in Children With Relapsed or Refractory Acute Lymphoblastic Leukemia

Completed
NCT01184898Not Applicable

Pilot Trial of Sirolimus/MEC in High Risk Acute Myelogenous Leukemia (AML)

Completed
NCT02632708Phase 1

Safety Study of AG-120 or AG-221 in Combination With Induction and Consolidation Therapy in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) With an IDH1 and/or IDH2 Mutation

Active Not Recruiting
NCT04778410Phase 2

Study of Magrolimab Combinations in Participants With Myeloid Malignancies

Terminated

Drug Details

Intervention Type
DRUG
Total Trials
98