Success Metrics

Clinical Success Rate
100.0%

Based on 9 completed trials

Completion Rate
100%(9/9)
Active Trials
6(35%)
Results Posted
78%(7 trials)

Phase Distribution

Ph phase_1
4
24%
Ph phase_2
9
53%
Ph phase_3
4
24%

Phase Distribution

4

Early Stage

9

Mid Stage

4

Late Stage

Phase Distribution17 total trials
Phase 1Safety & dosage
4(23.5%)
Phase 2Efficacy & side effects
9(52.9%)
Phase 3Large-scale testing
4(23.5%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

90.0%

9 of 10 finished

Non-Completion Rate

10.0%

1 ended early

Currently Active

6

trials recruiting

Total Trials

17

all time

Status Distribution
Active(6)
Completed(9)
Terminated(1)
Other(1)

Detailed Status

Completed9
Recruiting4
Active, not recruiting2
Withdrawn1
unknown1

Development Timeline

Analytics

Development Status

Total Trials
17
Active
6
Success Rate
100.0%
Most Advanced
Phase 3

Trials by Phase

Phase 14 (23.5%)
Phase 29 (52.9%)
Phase 34 (23.5%)

Trials by Status

completed953%
withdrawn16%
recruiting424%
active_not_recruiting212%
unknown16%

Recent Activity

Clinical Trials (17)

Showing 17 of 17 trials
NCT06890338Phase 2

A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.

Recruiting
NCT06365853Phase 2

A Study of Ocular Toxicity Evaluation and Mitigation During Treatment With Mirvetuximab Soravtansine in Participants With Recurrent Ovarian Cancer With High Folate Receptor-Alpha Expression

Recruiting
NCT06682988Phase 2

A Study to Assess Adverse Events and Change in Disease Activity in Participants With Platinum-Resistant Advanced High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancers With High Folate Receptor-Alpha Expression Treated With Intravenously (IV) Infused Mirvetuximab Soravtansine

Recruiting
NCT05041257Phase 2

Mirvetuximab Soravtansine Monotherapy in Platinum-Sensitive Epithelial, Peritoneal, and Fallopian Tube Cancers

Completed
NCT07059845Phase 2

A Study to Assess Adverse Events and Change in Disease Activity of Multiple Treatment Combinations With Intravenous Mirvetuximab Soravtansine in Adult Participants With Ovarian Cancer

Recruiting
NCT05456685Phase 2

Mirvetuximab Soravtansine (MIRV) With Carboplatin in Second-line Treatment of Folate Receptor Alpha (FRα) Expressing, Platinum-sensitive Epithelial Ovarian Cancer

Active Not Recruiting
NCT04209855Phase 3

A Study of Mirvetuximab Soravtansine vs. Investigator's Choice (IC) of Chemotherapy in Platinum-Resistant, Advanced High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancers With High Folate Receptor-Alpha (FRα) Expression

Completed
NCT04274426Phase 2

Mirvetuximab Soravtansine (IMGN853), in Folate Receptor Alpha (FRα) High Recurrent Ovarian Cancer

Active Not Recruiting
NCT03552471Phase 1

Mirvetuximab Soravtansine and Rucaparib Camsylate in Treating Participants With Recurrent Endometrial, Ovarian, Fallopian Tube or Primary Peritoneal Cancer

Completed
NCT04296890Phase 3

A Study of Mirvetuximab Soravtansine in Platinum-Resistant, Advanced High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancers With High Folate Receptor-Alpha Expression

Completed
NCT02606305Phase 1

Study of Mirvetuximab Soravtansine in Combination With Bevacizumab, Carboplatin, Pegylated Liposomal Doxorubicin, Pembrolizumab, or Bevacizumab + Carboplatin in Participants With Folate Receptor Alpha (FRα) Positive Advanced Epithelial Ovarian Cancer, Primary Peritoneal, or Fallopian Tube Cancer

Completed
NCT02996825Phase 1

Mirvetuximab Soravtansine and Gemcitabine Hydrochloride in Treating Patients With FRalpha-Positive Recurrent Ovarian, Primary Peritoneal, Fallopian Tube, Endometrial, or Triple Negative Breast Cancer

Completed
NCT05622890Phase 3

A Single-arm Clinical Trial of IMGN853 in Chinese Adult Patients With Platinum-resistant, Epithelial Ovarian Cancer

Unknown
NCT01609556Phase 1

First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Mirvetuximab Soravtansine in Adults With Ovarian Cancer and Other Folate Receptor 1 (FOLR1)-Positive Solid Tumors

Completed
NCT03106077Phase 2

Mirvetuximab Soravtansine as First Line in Treating Patients With Triple Negative Breast Cancer

Completed
NCT02631876Phase 3

A Study of Mirvetuximab Soravtansine vs. Investigator's Choice of Chemotherapy in Women With Folate Receptor (FR) Alpha Positive Advanced Epithelial Ovarian Cancer (EOC), Primary Peritoneal or Fallopian Tube Cancer

Completed
NCT03836157Phase 2

Mirvetuximab Soravtansine (IMGN853) and Bevacizumab in Patients With Endometrial Cancer

Withdrawn

All 17 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
17