Success Metrics

Clinical Success Rate
100.0%

Based on 8 completed trials

Completion Rate
100%(8/8)
Active Trials
0(0%)
Results Posted
50%(4 trials)

Phase Distribution

Ph phase_2
2
25%
Ph phase_3
3
38%
Ph phase_1
3
38%

Phase Distribution

3

Early Stage

2

Mid Stage

3

Late Stage

Phase Distribution8 total trials
Phase 1Safety & dosage
3(37.5%)
Phase 2Efficacy & side effects
2(25.0%)
Phase 3Large-scale testing
3(37.5%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

100.0%

8 of 8 finished

Non-Completion Rate

0.0%

0 ended early

Currently Active

0

trials recruiting

Total Trials

8

all time

Status Distribution
Completed(8)

Detailed Status

Completed8

Development Timeline

Analytics

Development Status

Total Trials
8
Active
0
Success Rate
100.0%
Most Advanced
Phase 3

Trials by Phase

Phase 13 (37.5%)
Phase 22 (25.0%)
Phase 33 (37.5%)

Trials by Status

completed8100%

Recent Activity

0 active trials
Showing 5 of 8
completedphase_2

Measure Liver Fat Content After ISIS 301012 (Mipomersen) Administration

NCT00362180
completedphase_3

Safety and Efficacy of Mipomersen in Patients With Severe Hypercholesterolemia on a Maximally Tolerated Lipid-Lowering Regimen and Who Are Not on Apheresis

NCT00794664
completedphase_3

Study to Assess the Safety and Efficacy of ISIS 301012 (Mipomersen) in Homozygous Familial Hypercholesterolemia

NCT00607373
completedphase_2

Safety and Efficacy Study of ISIS 301012 (Mipomersen) Administration in High Risk Statin Intolerant Subjects

NCT00707746
completedphase_1

A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Single Doses of Mipomersen in Japanese Healthy Volunteers

NCT01299298
View all 8 trials

Clinical Trials (8)

Showing 8 of 8 trials
NCT00362180Phase 2

Measure Liver Fat Content After ISIS 301012 (Mipomersen) Administration

Completed
NCT00794664Phase 3

Safety and Efficacy of Mipomersen in Patients With Severe Hypercholesterolemia on a Maximally Tolerated Lipid-Lowering Regimen and Who Are Not on Apheresis

Completed
NCT00607373Phase 3

Study to Assess the Safety and Efficacy of ISIS 301012 (Mipomersen) in Homozygous Familial Hypercholesterolemia

Completed
NCT00707746Phase 2

Safety and Efficacy Study of ISIS 301012 (Mipomersen) Administration in High Risk Statin Intolerant Subjects

Completed
NCT01299298Phase 1

A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Single Doses of Mipomersen in Japanese Healthy Volunteers

Completed
NCT01061814Phase 1

A Study to Evaluate 3 Different Dosing Regimens of Mipomersen Administered Via Subcutaneous Injections to Healthy Volunteers

Completed
NCT01414881Phase 1

Study to Assess the Effects of Mipomersen on Lipid and Lipoprotein Metabolism in Healthy Subjects

Completed
NCT01598948Phase 3

Effect of Mipomersen on LDL-Cholesterol Levels in Patients Treated by Regular Apheresis

Completed

All 8 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
8