Success Metrics

Clinical Success Rate
94.4%

Based on 17 completed trials

Completion Rate
94%(17/18)
Active Trials
2(8%)
Results Posted
18%(3 trials)
Terminated
1(4%)

Phase Distribution

Ph phase_2
12
48%
Ph phase_3
7
28%
Ph phase_4
1
4%

Phase Distribution

0

Early Stage

12

Mid Stage

8

Late Stage

Phase Distribution20 total trials
Phase 2Efficacy & side effects
12(60.0%)
Phase 3Large-scale testing
7(35.0%)
Phase 4Post-market surveillance
1(5.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

85.0%

17 of 20 finished

Non-Completion Rate

15.0%

3 ended early

Currently Active

2

trials recruiting

Total Trials

25

all time

Status Distribution
Active(3)
Completed(17)
Terminated(3)
Other(2)

Detailed Status

Completed17
unknown2
Withdrawn2
Terminated1
Active, not recruiting1
Recruiting1

Development Timeline

Analytics

Development Status

Total Trials
25
Active
2
Success Rate
94.4%
Most Advanced
Phase 4

Trials by Phase

Phase 212 (60.0%)
Phase 37 (35.0%)
Phase 41 (5.0%)

Trials by Status

terminated14%
unknown28%
withdrawn28%
active_not_recruiting14%
completed1768%
recruiting14%
not_yet_recruiting14%

Recent Activity

Clinical Trials (25)

Showing 20 of 25 trialsScroll for more
NCT07463040Phase 3

Study Comparing Several Drugs to Understand Which Work Against Cutaneous Leishmaniasis (CL)

Not Yet Recruiting
NCT04515186Phase 3

Combination, Miltefosine Monotherapy for Cutaneous Leishmaniasis in New World

Completed
NCT02427308

Treatment of Leishmaniasis With Impavido® (Miltefosine): Pregnancy Registry

Withdrawn
NCT06514560

OPTImizing MIltefosine Treatment for Cutaneous LEISHmaniasis Patients

Recruiting
NCT03129646Phase 3

Miltefosine/Paromomycin Phase III Trial for Treatment of Primary Visceral Leishmaniasis (VL) Patients in Eastern Africa

Completed
NCT02530697Phase 2

The Association of Miltefosine and Pentoxifylline to Treat Mucosal and Cutaneous Leishmaniasis: A Clinical Trial in Brazil

Active Not Recruiting
NCT03829917Phase 2

Oral Miltefosine Plus Topical Paromomycin In American Cutaneous Leishmaniasis

Completed
NCT01050907Phase 2

Miltefosine to Treat Mucocutaneous Leishmaniasis

Completed
NCT02429518

Dedicated QT Study in Bolivian Patients Taking Impavido® (Miltefosine) for Mucocutaneous Leishmaniasis

Completed
NCT02429505

Treatment of Leishmaniasis With Impavido® (Miltefosine): Higher-Weight Patient Registry

Withdrawn
NCT03399955Phase 2

Short Course Regimens for Treatment of PKDL (Sudan)

Unknown
NCT02687971Phase 2

Thermotherapy + a Short Course of Miltefosine for the Treatment of Uncomplicated Cutaneous Leishmaniasis in the New World¨

Completed
NCT02193022Phase 3

Miltefosine for Children With PKDL

Completed
NCT02011958Phase 3

Efficacy Trial of Ambisome Given Alone and Ambisome Given in Combination With Miltefosine for the Treatment of VL HIV Positive Ethiopian Patients.

Completed
NCT02431429

Spermiogram Assessment in Bolivian Patients Taking Impavido® (Miltefosine) for Mucocutaneous Leishmaniasis

Completed
NCT00471705Phase 3

Efficacy and Safety of Miltefosine or Thermotherapy for Cutaneous Leishmaniasis in Colombia.

Completed
NCT01067443Phase 2

Clinical Trial to Assess the Safety and Efficacy of Sodium Stibogluconate (SSG) and AmBisome® Combination, Miltefosine and AmBisome® and Miltefosine Alone for the Treatment Visceral Leishmaniasis in Eastern Africa

Completed
NCT01170949Phase 2

Efficacy and Safety of Miltefosine in Antihistamine Resistant Chronic Urticaria

Terminated
NCT02431143Phase 2

Pharmacokinetics/Safety of Miltefosine Allometric Dose for the Treatment of Visceral Leishmaniasis in Children in Eastern Africa

Completed
NCT01462500Phase 4

Pharmacokinetics of Miltefosine in Children and Adults

Completed

Drug Details

Intervention Type
DRUG
Total Trials
25