Success Metrics

Clinical Success Rate
92.0%

Based on 23 completed trials

Completion Rate
92%(23/25)
Active Trials
4(9%)
Results Posted
26%(6 trials)
Terminated
2(5%)

Phase Distribution

Ph not_applicable
14
33%
Ph phase_4
10
23%
Ph phase_2
6
14%
Ph early_phase_1
1
2%
Ph phase_3
5
12%
Ph phase_1
5
12%

Phase Distribution

6

Early Stage

6

Mid Stage

15

Late Stage

Phase Distribution41 total trials
Early Phase 1First-in-human
1(2.4%)
Phase 1Safety & dosage
5(12.2%)
Phase 2Efficacy & side effects
6(14.6%)
Phase 3Large-scale testing
5(12.2%)
Phase 4Post-market surveillance
10(24.4%)
N/ANon-phased studies
14(34.1%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

71.9%

23 of 32 finished

Non-Completion Rate

28.1%

9 ended early

Currently Active

4

trials recruiting

Total Trials

43

all time

Status Distribution
Active(5)
Completed(23)
Terminated(9)
Other(6)

Detailed Status

Completed23
Withdrawn7
unknown6
Recruiting3
Terminated2
Active, not recruiting1

Development Timeline

Analytics

Development Status

Total Trials
43
Active
4
Success Rate
92.0%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (2.4%)
Phase 15 (12.2%)
Phase 26 (14.6%)
Phase 35 (12.2%)
Phase 410 (24.4%)
N/A14 (34.1%)

Trials by Status

unknown614%
withdrawn716%
completed2353%
active_not_recruiting12%
recruiting37%
not_yet_recruiting12%
terminated25%

Recent Activity

Clinical Trials (43)

Showing 20 of 43 trialsScroll for more
NCT02429557Phase 1

Hemodynamic Mechanisms of Abdominal Compression in the Treatment of Orthostatic Hypotension in Autonomic Failure

Completed
NCT04620382Early Phase 1

Effect of Midodrine vs Abdominal Compression on Cardiovascular Risk Markers in Autonomic Failure Patients

Completed
NCT03482297Phase 1

Automated Abdominal Binder for Orthostatic Hypotension

Completed
NCT06091345Not Applicable

Midodrine Plus Albumin Versus Midodrine Alone to Prevent Cirrhosis Related Complications in Children With Cirrhosis and Ascites

Completed
NCT07422948Not Applicable

Efficacy and Safety of Early Initiation of Midodrine for Control and Prevention of Ascites and Its Related Complications in Acute-on-chronic Liver Failure.

Not Yet Recruiting
NCT05058612Phase 4

Midodrine for the Early Liberation of Vasopressor Support in the ICU (LIBERATE Multi-Site)

Recruiting
NCT02897063Phase 1

Effects of Midodrine and Droxidopa on Splanchnic Capacitance in Autonomic Failure

Recruiting
NCT00262470Phase 1

Treatment of Orthostatic Intolerance

Active Not Recruiting
NCT06319248Phase 2

MID-STEP (MIDodrine for Sepsis Treatment and Early vasoPressor Weaning) Trial

Recruiting
NCT02307565Phase 3

Blood Pressure, Cerebral Blood Flow and Cognition in Spinal Cord Injury

Completed
NCT05084534Not Applicable

Efficacy and Safety of Midodrine in Refractory or Recurrent Ascites in Children With Cirrhosis.

Withdrawn
NCT04208776Not Applicable

Efficacy of Combination of Midodrine With Propranolol in Preventing First Bleed in Decompensated Cirrhotics With Severe Ascites.

Completed
NCT04048707Phase 2

Angiotensin 2 for Hepatorenal Syndrome

Withdrawn
NCT06245590Not Applicable

Evaluation of Low-dose Albumin and Midodrine Versus Midodrine Alone in Outcome of Recurrent Ascites in Patients With Decompensated Cirrhosis.

Unknown
NCT06213935Not Applicable

Preoperative Oral Midodrine Versus Intraoperative Intravenous Norepinephrine in Preventing Post-spinal Anesthesia Hypotension in Cesarean Section: A Prospective Double-blind Randomized Clinical Trial

Unknown
NCT02990546Phase 3

Midodrine in the Recovery Phase of Septic Shock

Withdrawn
NCT04489589Phase 4

Midodrine for the Early Liberation of Vasopressor Support in the ICU

Completed
NCT03431194Not Applicable

Midodrine is Effective in Management of Intradialytic Hypotension Among Critically-ill Patients With Acute Kidney Injury

Completed
NCT04668859Phase 4

Midodrine as Novel Treatment of Post-Cardiopulmonary Bypass Vasoplegic Syndrome

Terminated
NCT02308124Phase 4

Treatment and Prognosis of Neurogenic Orthostatic Hypotension : A Prospective Randomized Study

Completed

Drug Details

Intervention Type
DRUG
Total Trials
43