Success Metrics

Clinical Success Rate
100.0%

Based on 7 completed trials

Completion Rate
100%(7/7)
Active Trials
1(13%)
Results Posted
14%(1 trials)

Phase Distribution

Ph phase_2
1
13%
Ph phase_1
6
75%
Ph phase_3
1
13%

Phase Distribution

6

Early Stage

1

Mid Stage

1

Late Stage

Phase Distribution8 total trials
Phase 1Safety & dosage
6(75.0%)
Phase 2Efficacy & side effects
1(12.5%)
Phase 3Large-scale testing
1(12.5%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

100.0%

7 of 7 finished

Non-Completion Rate

0.0%

0 ended early

Currently Active

1

trials recruiting

Total Trials

8

all time

Status Distribution
Active(1)
Completed(7)

Detailed Status

Completed7
Active, not recruiting1

Development Timeline

Analytics

Development Status

Total Trials
8
Active
1
Success Rate
100.0%
Most Advanced
Phase 3

Trials by Phase

Phase 16 (75.0%)
Phase 21 (12.5%)
Phase 31 (12.5%)

Trials by Status

active_not_recruiting113%
completed788%

Recent Activity

1 active trials
Showing 5 of 8
completedphase_2

Phase 2 Study of MGL-3196 in Patients With Non-Alcoholic Steatohepatitis (NASH)

NCT02912260
active_not_recruitingphase_3

A Phase 3 Study to Evaluate the Efficacy and Safety of MGL-3196 (Resmetirom) in Patients With NASH and Fibrosis

NCT03900429
completedphase_1

Phase 1 Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Multiple Oral Doses of MGL-3196 in Subjects With Varying Degrees of Hepatic Impairment and Healthy Matched Control Subjects

NCT04643795
completedphase_1

Drug Interaction Study of MGL-3196 With Rosuvastatin and Simvastatin

NCT02542969
completedphase_1

Drug Interaction Study of MGL-3196 With Clopidogrel

NCT04671069
View all 8 trials

Clinical Trials (8)

Showing 8 of 8 trials
NCT02912260Phase 2

Phase 2 Study of MGL-3196 in Patients With Non-Alcoholic Steatohepatitis (NASH)

Completed
NCT03900429Phase 3

A Phase 3 Study to Evaluate the Efficacy and Safety of MGL-3196 (Resmetirom) in Patients With NASH and Fibrosis

Active Not Recruiting
NCT04643795Phase 1

Phase 1 Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Multiple Oral Doses of MGL-3196 in Subjects With Varying Degrees of Hepatic Impairment and Healthy Matched Control Subjects

Completed
NCT02542969Phase 1

Drug Interaction Study of MGL-3196 With Rosuvastatin and Simvastatin

Completed
NCT04671069Phase 1

Drug Interaction Study of MGL-3196 With Clopidogrel

Completed
NCT04671056Phase 1

Drug Interaction Study of MGL-3196 With Pioglitazone

Completed
NCT03220165Phase 1

Radiolabeled Study to Determine the Mass Balance of [14C] MGL-3196

Completed
NCT02749578Phase 1

Drug Interaction Study of MGL-3196 With Atorvastatin

Completed

All 8 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
8