Success Metrics

Clinical Success Rate
100.0%

Based on 5 completed trials

Completion Rate
100%(5/5)
Active Trials
0(0%)
Results Posted
60%(3 trials)

Phase Distribution

Ph phase_3
1
14%
Ph not_applicable
1
14%
Ph phase_4
1
14%
Ph phase_2
3
43%
Ph phase_1
1
14%

Phase Distribution

1

Early Stage

3

Mid Stage

2

Late Stage

Phase Distribution7 total trials
Phase 1Safety & dosage
1(14.3%)
Phase 2Efficacy & side effects
3(42.9%)
Phase 3Large-scale testing
1(14.3%)
Phase 4Post-market surveillance
1(14.3%)
N/ANon-phased studies
1(14.3%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

83.3%

5 of 6 finished

Non-Completion Rate

16.7%

1 ended early

Currently Active

0

trials recruiting

Total Trials

7

all time

Status Distribution
Completed(5)
Terminated(1)
Other(1)

Detailed Status

Completed5
Withdrawn1
unknown1

Development Timeline

Analytics

Development Status

Total Trials
7
Active
0
Success Rate
100.0%
Most Advanced
Phase 4

Trials by Phase

Phase 11 (14.3%)
Phase 23 (42.9%)
Phase 31 (14.3%)
Phase 41 (14.3%)
N/A1 (14.3%)

Trials by Status

withdrawn114%
unknown114%
completed571%

Recent Activity

0 active trials
Showing 5 of 7
withdrawnphase_2

A Study of Methylnaltrexone Bromide (MNTX) in Participants With Advanced Pancreatic Cancer

NCT04083651
completedphase_1

Evaluate the Pharmacokinetics (PK) of Methylnaltrexone (MNTX) in Healthy Adult Subjects

NCT01366326
completedphase_2

Study of Subcutaneous Methylnaltrexone (MNTX) in the Treatment of Opioid-Induced Constipation During Rehabilitation After Orthopedic Procedures

NCT00640146
completedphase_4

Safety of Subcutaneous Methylnaltrexone for Opioid-Induced Constipation in Patients With Advanced Illness

NCT00672139
completednot_applicable

The Effect of Naloxone and Methylnaltrexone on Esophageal Sensitivity in Health

NCT03014843
View all 7 trials

Clinical Trials (7)

Showing 7 of 7 trials
NCT04083651Phase 2

A Study of Methylnaltrexone Bromide (MNTX) in Participants With Advanced Pancreatic Cancer

Withdrawn
NCT01366326Phase 1

Evaluate the Pharmacokinetics (PK) of Methylnaltrexone (MNTX) in Healthy Adult Subjects

Completed
NCT00640146Phase 2

Study of Subcutaneous Methylnaltrexone (MNTX) in the Treatment of Opioid-Induced Constipation During Rehabilitation After Orthopedic Procedures

Completed
NCT00672139Phase 4

Safety of Subcutaneous Methylnaltrexone for Opioid-Induced Constipation in Patients With Advanced Illness

Completed
NCT03014843Not Applicable

The Effect of Naloxone and Methylnaltrexone on Esophageal Sensitivity in Health

Completed
NCT01004393Phase 2

Methylnaltrexone for Opioid-induced Constipation in Cancer Patients

Completed
NCT01050595Phase 3

Methylnaltrexone for Treatment of Opiate-Induced Constipation in the Intensive Care Unit

Unknown

All 7 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
7