Success Metrics

Clinical Success Rate
91.3%

Based on 21 completed trials

Completion Rate
91%(21/23)
Active Trials
4(13%)
Results Posted
81%(17 trials)
Terminated
2(7%)

Phase Distribution

Ph phase_1
7
23%
Ph phase_2
3
10%
Ph phase_4
6
20%
Ph phase_3
14
47%

Phase Distribution

7

Early Stage

3

Mid Stage

20

Late Stage

Phase Distribution30 total trials
Phase 1Safety & dosage
7(23.3%)
Phase 2Efficacy & side effects
3(10.0%)
Phase 3Large-scale testing
14(46.7%)
Phase 4Post-market surveillance
6(20.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

87.5%

21 of 24 finished

Non-Completion Rate

12.5%

3 ended early

Currently Active

4

trials recruiting

Total Trials

30

all time

Status Distribution
Active(4)
Completed(21)
Terminated(3)
Other(2)

Detailed Status

Completed21
Recruiting3
Terminated2
unknown2
Active, not recruiting1
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
30
Active
4
Success Rate
91.3%
Most Advanced
Phase 4

Trials by Phase

Phase 17 (23.3%)
Phase 23 (10.0%)
Phase 314 (46.7%)
Phase 46 (20.0%)

Trials by Status

active_not_recruiting13%
terminated27%
unknown27%
withdrawn13%
recruiting310%
completed2170%

Recent Activity

Clinical Trials (30)

Showing 20 of 30 trialsScroll for more
NCT04939935Phase 3

Implementation of Metformin theraPy to Ease Decline of Kidney Function in Polycystic Kidney Disease (IMPEDE-PKD)

Recruiting
NCT07399535Phase 1

Clinical Investigation of Herbal Formulation and Its Efficacy in Polycystic Ovarian Syndrome

Recruiting
NCT04850846Phase 2

Investigation of Metformin for the Prevention of Progression of Precursor Multiple Myeloma

Active Not Recruiting
NCT02915198Phase 4

Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes

Recruiting
NCT04899349Phase 2

Study of Safety and Efficacy of Dapagliflozin + Metformin XR Versus Metformin XR in Participants With HR+, HER2-, Advanced Breast Cancer While on Treatment With Alpelisib and Fulvestrant

Terminated
NCT01267448Phase 4

Outpatient Discharge Therapy With Saxagliptin+MetforminXR vs GlipizideXL for Type 2 Diabetes With Severe Hyperglycemia

Completed
NCT03710460Phase 4

Effect of Dapagliflozin/Metformin XR vs Monotherapies on Anthropometric Indicators in Obesity

Unknown
NCT00643851Phase 3

An Efficacy & Safety Study of BMS-512148 in Combination With Metformin Extended Release Tablets

Completed
NCT01760447Phase 3

A Pooled Analysis of the Safety and Efficacy of MK-0431A and MK-0431A XR in Pediatric Participants With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin Therapy (Alone or in Combination With Insulin) (MK-0431A-170/MK-0431A-289)

Completed
NCT04047940Phase 1

A Study of LY900020 in Healthy Chinese Participants

Completed
NCT01864174Phase 4

Phase 4: Investigational Study to Evaluate Metformin XR Monotherapy Versus Metformin IR Monotherapy in Subjects With Type 2 Diabetes

Completed
NCT01999686Phase 3

PCOS Treatment Using DLBS3233, Metformin, and Combination of Both

Completed
NCT02145559Phase 1

A Pharmacodynamic Study of Sirolimus and Metformin in Patients With Advanced Solid Tumors

Completed
NCT02738879Phase 3

Randomized Sitagliptin Withdrawal Study (MK-0431-845)

Completed
NCT01733459Phase 3

Efficacy and Safety of DLBS3233 in Subjects With Polycystic Ovary Syndrome (PCOS)

Completed
NCT01809327Phase 3

A Study to Evaluate the Effectiveness, Safety, and Tolerability of Canagliflozin in Combination With Metformin in the Treatment of Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control With Diet and Exercise

Completed
NCT02022007Phase 3

Saxagliptin + Metformin Compared to Saxagliptin or Metformin Monotherapy in PCOS Women With Impaired Glucose Homeostasis

Completed
NCT01606007Phase 3

Safety and Efficacy of Combination Saxagliptin & Dapagliflozin Added to Metformin to Treat Subjects With Type 2 Diabetes

Completed
NCT02967276Phase 2

Clinical Activity of Metformin With High-dose of Dexamethasone in Relapse Multiple Myeloma

Unknown
NCT01434186Phase 3

A Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Saxagliptin (BMS-477118) in Combination With Metformin IR or Metformin XR in Pediatric Patients With Type 2 Diabetes Who Have Inadequate Glycemic Control on Metformin Alone

Completed

Drug Details

Intervention Type
DRUG
Total Trials
30