Success Metrics

Clinical Success Rate
81.2%

Based on 329 completed trials

Completion Rate
81%(329/405)
Active Trials
84(14%)
Results Posted
62%(205 trials)
Terminated
76(13%)

Phase Distribution

Ph not_applicable
27
5%
Ph phase_1
186
32%
Ph phase_4
3
1%
Ph early_phase_1
6
1%
Ph phase_3
73
12%
Ph phase_2
285
49%

Phase Distribution

192

Early Stage

285

Mid Stage

76

Late Stage

Phase Distribution580 total trials
Early Phase 1First-in-human
6(1.0%)
Phase 1Safety & dosage
186(32.1%)
Phase 2Efficacy & side effects
285(49.1%)
Phase 3Large-scale testing
73(12.6%)
Phase 4Post-market surveillance
3(0.5%)
N/ANon-phased studies
27(4.7%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

75.5%

329 of 436 finished

Non-Completion Rate

24.5%

107 ended early

Currently Active

84

trials recruiting

Total Trials

587

all time

Status Distribution
Active(92)
Completed(329)
Terminated(107)
Other(59)

Detailed Status

Completed329
Terminated76
unknown56
Recruiting44
Active, not recruiting40
Withdrawn31

Development Timeline

Analytics

Development Status

Total Trials
587
Active
84
Success Rate
81.2%
Most Advanced
Phase 4

Trials by Phase

Early Phase 16 (1.0%)
Phase 1186 (32.1%)
Phase 2285 (49.1%)
Phase 373 (12.6%)
Phase 43 (0.5%)
N/A27 (4.7%)

Trials by Status

active_not_recruiting407%
recruiting447%
suspended31%
unknown5610%
withdrawn315%
completed32956%
not_yet_recruiting81%
terminated7613%

Recent Activity

Clinical Trials (587)

Showing 20 of 587 trialsScroll for more
NCT01857934Phase 2

Therapy for Children With Advanced Stage Neuroblastoma

Completed
NCT03856216Phase 2

Inotuzumab Ozogamicin and Chemotherapy in Treating Patients With Leukemia or Lymphoma Undergoing Stem Cell Transplantation

Terminated
NCT05564390Phase 2

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Recruiting
NCT04384692Phase 2

Peritransplant Ruxolitinib for Patients With Primary and Secondary Myelofibrosis

Active Not Recruiting
NCT06172296Phase 3

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

Recruiting
NCT07257419Phase 1

CD45RA-depleted CD19-CAR T Cell Consolidation After TCRαβ+/CD19 B Cell-depleted Haploidentical Hematopoietic Cell Transplantation for Relapsed/Refractory CD19+ ALL and Lymphoma

Recruiting
NCT06954987Phase 2

Venetoclax or Placebo in Combination With Reduced-Intensity Conditioning Hematopoietic Cell (Bone Marrow/Blood Stem Cell) Transplant and as Maintenance Therapy After Transplant in Patients With Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)

Not Yet Recruiting
NCT03849651Phase 2

TCRαβ-depleted Progenitor Cell Graft With Additional Memory T-cell DLI, Plus Selected Use of Blinatumomab, in Naive T-cell Depleted Haploidentical Donor Hematopoietc Cell Transplantation for Hematologic Malignancies

Active Not Recruiting
NCT03786783Phase 2

Dinutuximab, Sargramostim, and Combination Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma

Active Not Recruiting
NCT02443077Phase 3

Ibrutinib Before and After Stem Cell Transplant in Treating Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma

Active Not Recruiting
NCT05088356Phase 1

Reduced Intensity Allogeneic HCT in Advanced Hematologic Malignancies w/T-Cell Depleted Graft

Recruiting
NCT01054196Phase 1

Lenalidomide Plus Melphalan as a Preparative Regimen for Autologous Stem Cell Transplantation in Relapsed Multiple Myeloma: A Phase 1 / 2 Study

Active Not Recruiting
NCT06692452Phase 2

Tazemetostat Plus CHOP in 1L T-cell Lymphoma

Withdrawn
NCT02251821Phase 2

JAK Inhibitor Before Donor Stem Cell Transplant in Treating Patients With Primary or Secondary Myelofibrosis

Completed
NCT04339101Phase 2

Itacitinib, Tacrolimus, and Sirolimus for the Prevention of GVHD in Patients With Acute Leukemia, Myelodysplastic Syndrome, or Myelofibrosis Undergoing Reduced Intensity Conditioning Donor Stem Cell Transplantation

Completed
NCT02333162Phase 1

Intensity Modulated Total Marrow Irradiation, Fludarabine Phosphate, and Melphalan in Treating Patients With Relapsed Hematologic Cancers Undergoing a Second Donor Stem Cell Transplant

Suspended
NCT04994977Phase 1

Intra-Arterial Chemotherapy for Newly Diagnosed, Residual, or Recurrent Atypical Choroid Plexus Papilloma and Choroid Plexus Carcinoma Prior to Second-Look Surgery

Terminated
NCT07281924Phase 1

Hepzato Kit and Opdualag for Metastatic Melanoma and Liver Metastasis

Recruiting
NCT01453088Phase 2

Auto Transplant High Dose Melphalan vs High Dose Melphalan+Bortezomib in Pts With Multiple Myeloma Age 65 Years or Older

Terminated
NCT05436418Phase 1

The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral Blood Stem Cell Transplantation

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
587