Success Metrics

Clinical Success Rate
81.3%

Based on 330 completed trials

Completion Rate
81%(330/406)
Active Trials
84(14%)
Results Posted
62%(206 trials)
Terminated
76(13%)

Phase Distribution

Ph early_phase_1
6
1%
Ph phase_1
186
31%
Ph phase_2
287
49%
Ph phase_3
74
13%
Ph not_applicable
28
5%
Ph phase_4
3
1%

Phase Distribution

192

Early Stage

287

Mid Stage

77

Late Stage

Phase Distribution584 total trials
Early Phase 1First-in-human
6(1.0%)
Phase 1Safety & dosage
186(31.8%)
Phase 2Efficacy & side effects
287(49.1%)
Phase 3Large-scale testing
74(12.7%)
Phase 4Post-market surveillance
3(0.5%)
N/ANon-phased studies
28(4.8%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

75.5%

330 of 437 finished

Non-Completion Rate

24.5%

107 ended early

Currently Active

84

trials recruiting

Total Trials

591

all time

Status Distribution
Active(95)
Completed(330)
Terminated(107)
Other(59)

Detailed Status

Completed330
Terminated76
unknown56
Recruiting44
Active, not recruiting40
Withdrawn31

Development Timeline

Analytics

Development Status

Total Trials
591
Active
84
Success Rate
81.3%
Most Advanced
Phase 4

Trials by Phase

Early Phase 16 (1.0%)
Phase 1186 (31.8%)
Phase 2287 (49.1%)
Phase 374 (12.7%)
Phase 43 (0.5%)
N/A28 (4.8%)

Trials by Status

active_not_recruiting407%
recruiting447%
completed33056%
suspended31%
unknown569%
terminated7613%
withdrawn315%
not_yet_recruiting112%

Recent Activity

Clinical Trials (591)

Showing 20 of 591 trialsScroll for more
NCT06172296Phase 3

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

Recruiting
NCT05564390Phase 2

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Recruiting
NCT00602641Phase 3

Melphalan, Prednisone, and Thalidomide or Lenalidomide in Treating Patients With Newly Diagnosed Multiple Myeloma

Active Not Recruiting
NCT05436418Phase 1

The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral Blood Stem Cell Transplantation

Recruiting
NCT04994977Phase 1

Intra-Arterial Chemotherapy for Newly Diagnosed, Residual, or Recurrent Atypical Choroid Plexus Papilloma and Choroid Plexus Carcinoma Prior to Second-Look Surgery

Terminated
NCT01702831Phase 2

Busulfan & Melphalan Conditioning for Autologous Stem Cell Transplant (ASCT) and Lenalidomide Maintenance

Completed
NCT03849651Phase 2

TCRαβ-depleted Progenitor Cell Graft With Additional Memory T-cell DLI, Plus Selected Use of Blinatumomab, in Naive T-cell Depleted Haploidentical Donor Hematopoietc Cell Transplantation for Hematologic Malignancies

Active Not Recruiting
NCT07624513Phase 3

Determination 2 - Isatuximab, Iberdomide, Bortezomib and Dexamethasone Induction, Followed by Risk- and Response-Adapted Consolidation and Maintenance Therapy, in Transplant-Eligible Patients With Newly Diagnosed Multiple Myeloma

Not Yet Recruiting
NCT07052370Phase 1

TCRαβ-depleted Progenitor Cell Graft With Early Memory T-cell DLI, Plus Selected Use of Blinatumomab, in naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies

Recruiting
NCT00544115Phase 2

Donor Peripheral Stem Cell Transplant in Treating Patients With Advanced Hematologic Cancer or Other Disorders

Active Not Recruiting
NCT03786783Phase 2

Dinutuximab, Sargramostim, and Combination Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma

Completed
NCT00114101Phase 3

Lenalidomide in Treating Patients With Multiple Myeloma Undergoing Autologous Stem Cell Transplant

Active Not Recruiting
NCT07281924Phase 1

Hepzato Kit and Opdualag for Metastatic Melanoma and Liver Metastasis

Recruiting
NCT01840566Phase 1

High Dose Therapy and Autologous Stem Cell Transplantation Followed by Infusion of Chimeric Antigen Receptor (CAR) Modified T-Cells Directed Against CD19+ B-Cells for Relapsed and Refractory Aggressive B Cell Non-Hodgkin Lymphoma

Active Not Recruiting
NCT07605416Phase 2

Testing an Experimental Approach to Treat Patients With Plasma Cell Leukemia, The QUANTUM Trial

Not Yet Recruiting
NCT00869232Phase 2

UARK 2008-02 A Trial for High-risk Myeloma Evaluating Accelerating and Sustaining Complete Remission

Active Not Recruiting
NCT02727803Phase 2

Personalized NK Cell Therapy in CBT

Recruiting
NCT07257419Phase 1

CD45RA-depleted CD19-CAR T Cell Consolidation After TCRαβ+/CD19 B Cell-depleted Haploidentical Hematopoietic Cell Transplantation for Relapsed/Refractory CD19+ ALL and Lymphoma

Recruiting
NCT02797470Phase 1

Gene Therapy in Treating Patients With Human Immunodeficiency Virus-Related Lymphoma Receiving Stem Cell Transplant

Active Not Recruiting
NCT06287944Phase 1

225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
591