Drug
Melflufen
Total Trials
5
Max Phase
—
Type
DRUG
Molecule
—
Success Metrics
Completion Rate
0%(0/4)
Active Trials
0(0%)
Terminated
4(80%)
Phase Distribution
Ph phase_3
2
40%
Ph phase_1
1
20%
Ph phase_2
2
40%
Phase Distribution
1
Early Stage
2
Mid Stage
2
Late Stage
Phase Distribution5 total trials
Phase 1Safety & dosage
1(20.0%)
Phase 2Efficacy & side effects
2(40.0%)
Phase 3Large-scale testing
2(40.0%)
Highest Phase Reached
Phase 3Trial Status & Enrollment
Completion Rate
0.0%
0 of 5 finished
Non-Completion Rate
100.0%
5 ended early
Currently Active
0
trials recruiting
Total Trials
5
all time
Status Distribution
Terminated(5)
Detailed Status
Terminated4
Withdrawn1
Development Timeline
Analytics
Development Status
Total Trials
5
Active
0
Success Rate
0.0%
Most Advanced
Phase 3
Trials by Phase
Phase 11 (20.0%)
Phase 22 (40.0%)
Phase 32 (40.0%)
Trials by Status
terminated480%
withdrawn120%
Recent Activity
0 active trials
Showing 5 of 5
withdrawnphase_2
Melflufen for Elderly Patients With Relapsed Myeloma
NCT06682637
terminatedphase_3
A Study of Melphalan Flufenamide (Melflufen)-Dex or Pomalidomide-dex for RRMM Patients Refractory to Lenalidomide
NCT03151811
terminatedphase_3
Study of Melflufen (Melphalan Flufenamide) in Combination With Daratumumab in Relapsed-Refractory Multiple Myeloma
NCT04649060
terminatedphase_2
PK of Melphalan During Treatment With Melflufen and Dexamethasone in Patients With RRMM and Impaired Renal Function
NCT03639610
terminatedphase_1
Safety and Efficacy of Melflufen and Dexamethasone in Relapsed and/or Relapsed-Refractory Multiple Myeloma Patients
NCT01897714
Clinical Trials (5)
Showing 5 of 5 trials
NCT06682637Phase 2
Melflufen for Elderly Patients With Relapsed Myeloma
NCT03151811Phase 3
A Study of Melphalan Flufenamide (Melflufen)-Dex or Pomalidomide-dex for RRMM Patients Refractory to Lenalidomide
NCT04649060Phase 3
Study of Melflufen (Melphalan Flufenamide) in Combination With Daratumumab in Relapsed-Refractory Multiple Myeloma
NCT03639610Phase 2
PK of Melphalan During Treatment With Melflufen and Dexamethasone in Patients With RRMM and Impaired Renal Function
NCT01897714Phase 1
Safety and Efficacy of Melflufen and Dexamethasone in Relapsed and/or Relapsed-Refractory Multiple Myeloma Patients
All 5 trials loaded
Drug Details
- Intervention Type
- DRUG
- Total Trials
- 5