Success Metrics

Clinical Success Rate
80.9%

Based on 114 completed trials

Completion Rate
81%(114/141)
Active Trials
27(11%)
Results Posted
35%(40 trials)
Terminated
27(11%)

Phase Distribution

Ph phase_2
72
29%
Ph phase_3
32
13%
Ph phase_4
25
10%
Ph early_phase_1
12
5%
Ph not_applicable
77
31%
Ph phase_1
27
11%

Phase Distribution

39

Early Stage

72

Mid Stage

57

Late Stage

Phase Distribution245 total trials
Early Phase 1First-in-human
12(4.9%)
Phase 1Safety & dosage
27(11.0%)
Phase 2Efficacy & side effects
72(29.4%)
Phase 3Large-scale testing
32(13.1%)
Phase 4Post-market surveillance
25(10.2%)
N/ANon-phased studies
77(31.4%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

73.1%

114 of 156 finished

Non-Completion Rate

26.9%

42 ended early

Currently Active

27

trials recruiting

Total Trials

247

all time

Status Distribution
Active(42)
Completed(114)
Terminated(42)
Other(49)

Detailed Status

Completed114
unknown48
Terminated27
Recruiting21
Withdrawn15
Not yet recruiting13

Development Timeline

Analytics

Development Status

Total Trials
247
Active
27
Success Rate
80.9%
Most Advanced
Phase 4

Trials by Phase

Early Phase 112 (4.9%)
Phase 127 (11.0%)
Phase 272 (29.4%)
Phase 332 (13.1%)
Phase 425 (10.2%)
N/A77 (31.4%)

Trials by Status

suspended10%
enrolling_by_invitation21%
active_not_recruiting62%
recruiting219%
unknown4819%
completed11446%
withdrawn156%
not_yet_recruiting135%
terminated2711%

Recent Activity

Clinical Trials (247)

Showing 20 of 247 trialsScroll for more
NCT00097474Phase 2

Effects of Hydrocortisone, Melatonin, and Placebo on Jet Lag

Completed
NCT06404112Phase 2

RECOVER-SLEEP: Platform Protocol, Appendix_B (CPSD)

Completed
NCT07617922Phase 2

Melatonin and Solifenacin for Double-J Ureteral Stent Symptoms

Recruiting
NCT05358834Not Applicable

Testing Effects of Melatonin on Uterine Contractions in Women

Recruiting
NCT07472075Phase 2

Melatonin Versus Placebo for Bipolar Disorder

Recruiting
NCT06226025Phase 2

Correcting Circadian Rhythms to Breakthrough in Bipolar Disorder

Recruiting
NCT07336277Phase 3

Sleep Quality and the Efficacy of a Multimodal Sleep Pathway in Hospitalized Orthopedic Trauma Patients

Not Yet Recruiting
NCT07568873Not Applicable

Melatonin vs Metoprolol or Dexmedetomidine to Improve Surgical Field in FESS

Completed
NCT04831398Phase 4

The Effects of Acute Melatonin Supplementation on Cardiovascular Responses to Sympathetic Activation

Active Not Recruiting
NCT05701969Early Phase 1

Effect of Melatonin on Sleep Patterns of Resident Trainees During Night Float Shift

Recruiting
NCT07550751Phase 4

Optimal Dosage of Melatonin for Preoperative Sedation in FESS

Completed
NCT07549295Phase 1

Melatonin and Perinatal Outcomes in MVM-Related Fetal Growth Restriction (MIMVMFGR)

Enrolling By Invitation
NCT04547439Phase 2

Sleep, Diabetic Retinopathy and Melatonin

Recruiting
NCT05716906Not Applicable

Melatonin and Sleep Spindles in Autism

Active Not Recruiting
NCT07503600Phase 3

The Effect of Adjunctive Melatonin With Colistin in Patients With Multidrug-Resistant Gram-Negative Bacterial Infections

Not Yet Recruiting
NCT05713877Phase 2

Melatonin for Treatment of Delirium in Critically Ill Adult Patients

Recruiting
NCT07475156Phase 4

The Effect of Dexmedetomidine Infusion Alone Versus the Combination of Dexmedetomidine and Melatonin on Reduction of Post-operative Delirium (POD) After Open Brain Surgeries

Completed
NCT03540485Phase 1

Safety and Efficacy of Melatonin in Patients With Multiple Progressive Primary Sclerosis

Terminated
NCT02642640Not Applicable

Interaction of Melatonin and MTNR1B Genotype on Glucose Control - Study 1

Completed
NCT04588233Not Applicable

Melatonin Adolescent Research Study

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
247