Success Metrics

Clinical Success Rate

81.0%

Based on 115 completed trials

Completion Rate

81%(115/142)

Active Trials

29(12%)

Results Posted

35%(40 trials)

Terminated

27(11%)

Phase Distribution

Ph early_phase_1

Ph not_applicable

31%

Ph phase_2

29%

Ph phase_1

11%

Ph phase_3

13%

Ph phase_4

10%

Phase Distribution

Early Stage

Mid Stage

Late Stage

Phase Distribution248 total trials

Early Phase 1First-in-human

12(4.8%)

Phase 1Safety & dosage

27(10.9%)

Phase 2Efficacy & side effects

73(29.4%)

Phase 3Large-scale testing

32(12.9%)

Phase 4Post-market surveillance

26(10.5%)

N/ANon-phased studies

78(31.5%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

73.2%

115 of 157 finished

Non-Completion Rate

26.8%

42 ended early

Currently Active

trials recruiting

Total Trials

250

all time

Status Distribution

Active(44)

Completed(115)

Terminated(42)

Other(49)

Detailed Status

Completed115

unknown48

Terminated27

Recruiting23

Withdrawn15

Not yet recruiting14

Development Timeline

Analytics

Development Status

Total Trials

250

Active

Success Rate

81.0%

Most Advanced

Phase 4

Trials by Phase

Early Phase 112 (4.8%)

Phase 127 (10.9%)

Phase 273 (29.4%)

Phase 332 (12.9%)

Phase 426 (10.5%)

N/A78 (31.5%)

Trials by Status

terminated2711%

enrolling_by_invitation10%

recruiting239%

not_yet_recruiting146%

suspended10%

completed11546%

unknown4819%

withdrawn156%

active_not_recruiting62%

Recent Activity

29 active trials

Showing 5 of 250

recruitingphase_3

Sleep Quality and the Efficacy of a Multimodal Sleep Pathway in Hospitalized Orthopedic Trauma Patients

NCT07336277

completedphase_2

Clinical Trials (250)

Showing 20 of 250 trialsScroll for more

NCT07336277Phase 3

Sleep Quality and the Efficacy of a Multimodal Sleep Pathway in Hospitalized Orthopedic Trauma Patients

Recruiting

NCT00097474Phase 2

Effects of Hydrocortisone, Melatonin, and Placebo on Jet Lag

Completed

NCT07721324Phase 2

Effect of Melatonin Administration on Systemic Lupus Erythematosus Patients

Not Yet Recruiting

NCT07036796Phase 2

Effect of Melatonin in Patients With Diabetic Peripheral Neuropathy

Recruiting

NCT07375342Not Applicable

Melatonin for Post Tonsillectomy Emergence Agitation in Pediatric

Recruiting

NCT07691996Phase 4

Effects of Melatonin on Sleep Architecture of Critically Ill Patients in the ICU

Not Yet Recruiting

NCT04588233Not Applicable

Melatonin Adolescent Research Study

Recruiting

NCT06404112Phase 2

RECOVER-SLEEP: Platform Protocol, Appendix_B (CPSD)

Completed

NCT07669766Not Applicable

Somato® (Phytomelatonin) Versus Synthetic Melatonin and Placebo on Sleep Quality

Completed

NCT02621944Early Phase 1

Melatonin as a Neuroprotective Therapy in Neonates With HIE Undergoing Hypothermia

Recruiting

NCT07617922Phase 2

Melatonin and Solifenacin for Double-J Ureteral Stent Symptoms

Recruiting

NCT05358834Not Applicable

Testing Effects of Melatonin on Uterine Contractions in Women

Recruiting

NCT07472075Phase 2

Melatonin Versus Placebo for Bipolar Disorder

Recruiting

NCT06226025Phase 2

Correcting Circadian Rhythms to Breakthrough in Bipolar Disorder

Recruiting

NCT07568873Not Applicable

Melatonin vs Metoprolol or Dexmedetomidine to Improve Surgical Field in FESS

Completed

NCT04831398Phase 4

The Effects of Acute Melatonin Supplementation on Cardiovascular Responses to Sympathetic Activation

Active Not Recruiting

NCT05701969Early Phase 1

Effect of Melatonin on Sleep Patterns of Resident Trainees During Night Float Shift

Recruiting

NCT07549295Phase 1

Melatonin and Perinatal Outcomes in MVM-Related Fetal Growth Restriction (MIMVMFGR)

Enrolling By Invitation

NCT07550751Phase 4

Optimal Dosage of Melatonin for Preoperative Sedation in FESS

Completed

NCT04547439Phase 2

Sleep, Diabetic Retinopathy and Melatonin

Recruiting

Drug Details

Intervention Type: DIETARY SUPPLEMENT
Total Trials: 250