Success Metrics

Clinical Success Rate
81.1%

Based on 116 completed trials

Completion Rate
81%(116/143)
Active Trials
30(12%)
Results Posted
34%(40 trials)
Terminated
27(11%)

Phase Distribution

Ph phase_1
27
11%
Ph phase_2
73
29%
Ph phase_4
26
10%
Ph early_phase_1
12
5%
Ph phase_3
32
13%
Ph not_applicable
82
32%

Phase Distribution

39

Early Stage

73

Mid Stage

58

Late Stage

Phase Distribution252 total trials
Early Phase 1First-in-human
12(4.8%)
Phase 1Safety & dosage
27(10.7%)
Phase 2Efficacy & side effects
73(29.0%)
Phase 3Large-scale testing
32(12.7%)
Phase 4Post-market surveillance
26(10.3%)
N/ANon-phased studies
82(32.5%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

73.4%

116 of 158 finished

Non-Completion Rate

26.6%

42 ended early

Currently Active

30

trials recruiting

Total Trials

254

all time

Status Distribution
Active(47)
Completed(116)
Terminated(42)
Other(49)

Detailed Status

Completed116
unknown48
Terminated27
Recruiting23
Withdrawn15
Not yet recruiting15

Development Timeline

Analytics

Development Status

Total Trials
254
Active
30
Success Rate
81.1%
Most Advanced
Phase 4

Trials by Phase

Early Phase 112 (4.8%)
Phase 127 (10.7%)
Phase 273 (29.0%)
Phase 332 (12.7%)
Phase 426 (10.3%)
N/A82 (32.5%)

Trials by Status

suspended10%
completed11646%
unknown4819%
withdrawn156%
recruiting239%
not_yet_recruiting156%
active_not_recruiting73%
terminated2711%
enrolling_by_invitation21%

Recent Activity

Clinical Trials (254)

Showing 20 of 254 trialsScroll for more
NCT07850934Not Applicable

Effect of Melatonin on Pulmonary Hypertension in Full Term Neonates

Recruiting
NCT03954899Not Applicable

Disease Modifying Potential of 5mg of Melatonin on Cognition and Brain Health in Aging

Recruiting
NCT00097474Phase 2

Effects of Hydrocortisone, Melatonin, and Placebo on Jet Lag

Completed
NCT07842900Not Applicable

Oral Melatonin as Adjunctive Therapy in Adults With Atopic Dermatitis

Not Yet Recruiting
NCT05474846Phase 2

Combination Therapy for Treatment of Sleep Disturbance in Patients With Advanced Cancer

Active Not Recruiting
NCT07825961Not Applicable

Efficacy of Melatonin in the Treatment of Diabetic Nephropathy Compared With Folic Acid

Completed
NCT05541276Phase 3

MELAtonin for Prevention of Postoperative Agitation and Emergence Delirium in Children

Recruiting
NCT06382610Not Applicable

Pharmacokinetics of Melatonin Administered in Oral, Lotion, and Bubble Bath Formulations

Completed
NCT07743255Not Applicable

Preventive Role of Melatonin and Propranolol Administration in Pediatric Migraine

Enrolling By Invitation
NCT07336277Phase 3

Sleep Quality and the Efficacy of a Multimodal Sleep Pathway in Hospitalized Orthopedic Trauma Patients

Recruiting
NCT07721324Phase 2

Effect of Melatonin Administration on Systemic Lupus Erythematosus Patients

Not Yet Recruiting
NCT07036796Phase 2

Effect of Melatonin in Patients With Diabetic Peripheral Neuropathy

Recruiting
NCT07375342Not Applicable

Melatonin for Post Tonsillectomy Emergence Agitation in Pediatric

Recruiting
NCT07691996Phase 4

Effects of Melatonin on Sleep Architecture of Critically Ill Patients in the ICU

Not Yet Recruiting
NCT04588233Not Applicable

Melatonin Adolescent Research Study

Recruiting
NCT06404112Phase 2

RECOVER-SLEEP: Platform Protocol, Appendix_B (CPSD)

Completed
NCT07669766Not Applicable

Somato® (Phytomelatonin) Versus Synthetic Melatonin and Placebo on Sleep Quality

Completed
NCT02621944Early Phase 1

Melatonin as a Neuroprotective Therapy in Neonates With HIE Undergoing Hypothermia

Recruiting
NCT07617922Phase 2

Melatonin and Solifenacin for Double-J Ureteral Stent Symptoms

Recruiting
NCT05358834Not Applicable

Testing Effects of Melatonin on Uterine Contractions in Women

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
254