Success Metrics

Clinical Success Rate
78.1%

Based on 25 completed trials

Completion Rate
78%(25/32)
Active Trials
6(13%)
Results Posted
40%(10 trials)
Terminated
7(15%)

Phase Distribution

Ph phase_1
4
9%
Ph not_applicable
2
4%
Ph phase_4
3
7%
Ph phase_2
26
57%
Ph phase_3
11
24%

Phase Distribution

4

Early Stage

26

Mid Stage

14

Late Stage

Phase Distribution46 total trials
Phase 1Safety & dosage
4(8.7%)
Phase 2Efficacy & side effects
26(56.5%)
Phase 3Large-scale testing
11(23.9%)
Phase 4Post-market surveillance
3(6.5%)
N/ANon-phased studies
2(4.3%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

71.4%

25 of 35 finished

Non-Completion Rate

28.6%

10 ended early

Currently Active

6

trials recruiting

Total Trials

46

all time

Status Distribution
Active(8)
Completed(25)
Terminated(10)
Other(3)

Detailed Status

Completed25
Terminated7
Active, not recruiting4
unknown3
Withdrawn3
Recruiting2

Development Timeline

Analytics

Development Status

Total Trials
46
Active
6
Success Rate
78.1%
Most Advanced
Phase 4

Trials by Phase

Phase 14 (8.7%)
Phase 226 (56.5%)
Phase 311 (23.9%)
Phase 43 (6.5%)
N/A2 (4.3%)

Trials by Status

recruiting24%
completed2554%
active_not_recruiting49%
not_yet_recruiting24%
terminated715%
unknown37%
withdrawn37%

Recent Activity

Clinical Trials (46)

Showing 20 of 46 trialsScroll for more
NCT04939090Phase 3

Olanzapine Versus Megestrol Acetate for the Treatment of Loss of Appetite Among Advanced Cancer Patients

Active Not Recruiting
NCT05538897Phase 1

Testing the Addition of the AKT Inhibitor, Ipatasertib, to Treatment With the Hormonal Agent Megestrol Acetate for Recurrent or Metastatic Endometrial Cancers

Active Not Recruiting
NCT07436793Phase 2

Progestins for the Treatment of Endometrial Cancer or Precancers of the Uterus Before Surgery, The Pro-Window Trial

Not Yet Recruiting
NCT04576104Phase 2

Megestrol Acetate Compared With Megestrol Acetate and Metformin to Prevent Endometrial Cancer

Active Not Recruiting
NCT03671811Phase 2

Megestrol Acetate With or Without Pterostilbene in Treating Patients With Endometrial Cancer Undergoing Hysterectomy

Active Not Recruiting
NCT06998758Phase 3

Megestrol Acetate in Improving Neoadjuvant Chemotherapy-Related Weight Loss in Locally Advanced CRC

Recruiting
NCT07254416Phase 4

A Study on Nausea and Vomiting Caused by T-DXd in Breast Cancer Patients

Not Yet Recruiting
NCT03815019Phase 4

iKanEat: A Randomized-controlled, Multi-center Trial of Megestrol for Chronic Oral Food Refusal in Children

Completed
NCT04491643Phase 2

Megestrol Acetate Plus Rosuvastatin in Young Women With Early Endometrial Carcinoma

Completed
NCT05255653Phase 2

Refining Adjuvant Treatment in Endometrial Cancer Based on Molecular Features

Recruiting
NCT03241888Phase 2

Megestrol Acetate Plus LNG-IUS in Young Women With Endometrial Atypical Hyperplasia

Completed
NCT04607252Phase 2

Metformin Plus Megestrol Acetate As a Fertility-sparing Treatment in Patients with Atypical Endometrial Hyperplasia

Terminated
NCT04491682Phase 2

Megestrol Acetate Plus Rosuvastatin in Young Women With Atypical Endometrial Hyperplasia

Completed
NCT05332483Phase 1

Study of Megestrol Acetate in Grade 2 Endometrioid Endometrial Cancer

Terminated
NCT04897217Phase 3

Levonorgestrel-Releasing Intrauterine System (LNG-IUS) in the Management of Atypical Endometrial Hyperplasia

Withdrawn
NCT05380479Phase 2

Mirtazapine Versus Megestrol Acetate in Treatment of Anorexia-cachexia in Advanced Cancer Patients.

Unknown
NCT02269670Phase 2

Phase II Study of Everolimus Beyond Progression

Terminated
NCT00001079Phase 2

A Study of Megestrol Acetate Alone or in Combination With Testosterone Enanthate Drug in the Treatment of HIV-Associated Weight Loss

Completed
NCT01968317Phase 2

Megestrol Acetate Plus Metformin to Megestrol Acetate in Patients With Endometrial Atypical Hyperplasia or Early Stage Endometrial Adenocarcinoma

Completed
NCT00031785Phase 3

Megestrol in Treating Patients Who Are Undergoing Radiation Therapy for Lung Cancer

Completed

Drug Details

Intervention Type
DRUG
Total Trials
46