Success Metrics

Clinical Success Rate
75.0%

Based on 15 completed trials

Completion Rate
75%(15/20)
Active Trials
2(8%)
Results Posted
73%(11 trials)
Terminated
5(20%)

Phase Distribution

Ph phase_4
1
4%
Ph phase_2
3
12%
Ph phase_3
13
52%
Ph phase_1
7
28%

Phase Distribution

7

Early Stage

3

Mid Stage

14

Late Stage

Phase Distribution24 total trials
Phase 1Safety & dosage
7(29.2%)
Phase 2Efficacy & side effects
3(12.5%)
Phase 3Large-scale testing
13(54.2%)
Phase 4Post-market surveillance
1(4.2%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

68.2%

15 of 22 finished

Non-Completion Rate

31.8%

7 ended early

Currently Active

2

trials recruiting

Total Trials

25

all time

Status Distribution
Active(2)
Completed(15)
Terminated(7)
Other(1)

Detailed Status

Completed15
Terminated5
Withdrawn2
Active, not recruiting2
unknown1

Development Timeline

Analytics

Development Status

Total Trials
25
Active
2
Success Rate
75.0%
Most Advanced
Phase 4

Trials by Phase

Phase 17 (29.2%)
Phase 23 (12.5%)
Phase 313 (54.2%)
Phase 41 (4.2%)

Trials by Status

withdrawn28%
unknown14%
completed1560%
terminated520%
active_not_recruiting28%

Recent Activity

Clinical Trials (25)

Showing 20 of 25 trialsScroll for more
NCT00525616Phase 3

Efficiency and Tolerance of Rituximab (mabthéra) in Bullous Pemphigoid

Completed
NCT01350882Phase 3

Impact of Treatment With Rituximab on the Progression of Humoral Acute Rejection After Renal Transplantation

Completed
NCT04833114Phase 3

Polatuzumab Vedotin Plus Rituximab, Ifosfamide, Carboplatin and Etoposide (Pola-R-ICE) Versus R-ICE Alone in Second Line Treatment of Diffuse Large B-cell Lymphoma (DLBCL)

Active Not Recruiting
NCT06175338Phase 1

Study, Evaluating Pharmacokinetics, Pharmacodynamics, Immunogenicity and Safety Profiles of Rituximab Compared to MabThera® in Patients With Rheumatoid Arthritis

Active Not Recruiting
NCT03976102Phase 3

Compare Efficacy, Safety, and Immunogenicity of Proposed Rituximab Biosimilar (DRL_RI) With MabThera® in LTB Follicular Lymphoma

Completed
NCT04680962Phase 3

MabionCD20® Compared to MabThera® and Rituxan® in Patients With Rheumatoid Arthritis

Withdrawn
NCT02149121Phase 3

PK Similarity Prospective Phase 3 Study in Patients With Rheumatoid Arthritis

Completed
NCT03289182

An Observational Study of MabThera Subcutaneous (SC) Safety in Participants With Non-Hodgkin's Lymphoma (NHL) or Chronic Lymphocytic Leukemia (CLL)

Completed
NCT04671420Phase 3

Evaluate the Efficacy and Safety of HLX01 Versus Mabthera in Patients With Low Tumour Burden Follicular Lymphoma.

Withdrawn
NCT02809053Phase 3

A Randomized, Double-blind, Multi-center, Multi-national Trial to Evaluate the Efficacy, Safety, and Immunogenicity of SAIT101 Versus Rituximab as a First-line Immunotherapy Treatment in Patients With Low Tumor Burden Follicular Lymphoma

Completed
NCT02819726Phase 1

PK, PD, Safety, and Efficacy of SAIT101 Versus MabThera® Versus Rituxan® in Patients With Rheumatoid Arthritis

Completed
NCT02296775Phase 1

Comparative Pharmacokinetic, Pharmacodynamic, Safety and Efficacy Study of Three Anti-CD20 Monoclonal Antibodies in Patients With Moderate to Severe Rheumatoid Arthritis

Completed
NCT03161457Phase 1

A Study of JHL1101 Versus MabThera® in Subjects With Severe Rheumatoid Arthritis

Terminated
NCT03670901Phase 3

A Study to Compare the Efficacy and Safety of JHL1101 Versus Rituximab in Patients With Previously Untreated Diffuse Large B-Cell Lymphoma (DLBCL)

Terminated
NCT01526057Phase 2

A Pharmacokinetic/Pharmacodynamic Study Comparing PF-05280586 To Rituximab In Subjects With Active Rheumatoid Arthritis With An Inadequate Response To TNF Inhibitors (REFLECTIONS B328-01)

Completed
NCT02268045Phase 3

Study of RTXM83 Plus CHOP Chemotherapy Versus a Rituximab Plus CHOP Therapy in Patients With Non Hodgkin's Lymphoma

Completed
NCT03061838Phase 1

Safety, Tolerability, PK and PD of Biosimilar Drug Ritumax® Compared to Original Drug MabThera®

Terminated
NCT02213263Phase 3

A Study Of PF-05280586 (Rituximab-Pfizer) Or MabThera® (Rituximab-EU) For The First-Line Treatment Of Patients With CD20-Positive, Low Tumor Burden, Follicular Lymphoma (REFLECTIONS B328-06)

Completed
NCT01638715Phase 4

A Randomized, Multi-Center Biomarker Trial to Predict Therapeutic Responses of Patients With Rheumatoid Arthritis to a Specific Biologic Mode of Action

Completed
NCT01950273Phase 1

Pharmacokinetics and Pharmacodynamics of BI 695500 vs. Rituximab as First Line-treatment in Patients With Low Tumor Burden Follicular Lymphoma

Completed

Drug Details

Intervention Type
DRUG
Total Trials
25