Success Metrics

Clinical Success Rate
83.3%

Based on 5 completed trials

Completion Rate
83%(5/6)
Active Trials
1(13%)
Results Posted
120%(6 trials)
Terminated
1(13%)

Phase Distribution

Ph phase_1
1
13%
Ph phase_2
3
38%
Ph phase_3
3
38%

Phase Distribution

1

Early Stage

3

Mid Stage

3

Late Stage

Phase Distribution7 total trials
Phase 1Safety & dosage
1(14.3%)
Phase 2Efficacy & side effects
3(42.9%)
Phase 3Large-scale testing
3(42.9%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

83.3%

5 of 6 finished

Non-Completion Rate

16.7%

1 ended early

Currently Active

1

trials recruiting

Total Trials

8

all time

Status Distribution
Active(1)
Completed(5)
Terminated(1)
Other(1)

Detailed Status

Completed5
Recruiting1
unknown1
Terminated1

Development Timeline

Analytics

Development Status

Total Trials
8
Active
1
Success Rate
83.3%
Most Advanced
Phase 3

Trials by Phase

Phase 11 (14.3%)
Phase 23 (42.9%)
Phase 33 (42.9%)

Trials by Status

recruiting113%
unknown113%
terminated113%
completed563%

Recent Activity

1 active trials
Showing 5 of 8
completedphase_3

A Study to Evaluate Lumasiran in Patients With Advanced Primary Hyperoxaluria Type 1

NCT04152200
completedphase_3

A Study of Lumasiran in Infants and Young Children With Primary Hyperoxaluria Type 1

NCT03905694
recruitingphase_2

Lumasiran in Hyperoxalaemic Patients on Haemodialysis

NCT06225544
completedphase_3

A Study to Evaluate Lumasiran in Children and Adults With Primary Hyperoxaluria Type 1

NCT03681184
terminatedphase_2

A Study to Evaluate Lumasiran in Adults With Recurrent Calcium Oxalate Kidney Stone Disease and Elevated Urinary Oxalate Levels

NCT05161936
View all 8 trials

Clinical Trials (8)

Showing 8 of 8 trials
NCT04152200Phase 3

A Study to Evaluate Lumasiran in Patients With Advanced Primary Hyperoxaluria Type 1

Completed
NCT03905694Phase 3

A Study of Lumasiran in Infants and Young Children With Primary Hyperoxaluria Type 1

Completed
NCT06225544Phase 2

Lumasiran in Hyperoxalaemic Patients on Haemodialysis

Recruiting
NCT03681184Phase 3

A Study to Evaluate Lumasiran in Children and Adults With Primary Hyperoxaluria Type 1

Completed
NCT05161936Phase 2

A Study to Evaluate Lumasiran in Adults With Recurrent Calcium Oxalate Kidney Stone Disease and Elevated Urinary Oxalate Levels

Terminated
NCT03350451Phase 2

An Extension Study of an Investigational Drug, Lumasiran (ALN-GO1), in Participants With Primary Hyperoxaluria Type 1

Completed
NCT04125472

Expanded Access Protocol to Provide Lumasiran to Patients With Primary Hyperoxaluria Type 1

Unknown
NCT02706886Phase 1

Study of Lumasiran in Healthy Adults and Patients With Primary Hyperoxaluria Type 1

Completed

All 8 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
8