Success Metrics

Clinical Success Rate
90.0%

Based on 36 completed trials

Completion Rate
90%(36/40)
Active Trials
2(5%)
Results Posted
97%(35 trials)
Terminated
4(10%)

Phase Distribution

Ph phase_4
9
21%
Ph phase_2
4
10%
Ph not_applicable
7
17%
Ph phase_1
3
7%
Ph phase_3
18
43%

Phase Distribution

3

Early Stage

4

Mid Stage

27

Late Stage

Phase Distribution41 total trials
Phase 1Safety & dosage
3(7.3%)
Phase 2Efficacy & side effects
4(9.8%)
Phase 3Large-scale testing
18(43.9%)
Phase 4Post-market surveillance
9(22.0%)
N/ANon-phased studies
7(17.1%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

90.0%

36 of 40 finished

Non-Completion Rate

10.0%

4 ended early

Currently Active

2

trials recruiting

Total Trials

42

all time

Status Distribution
Active(2)
Completed(36)
Terminated(4)

Detailed Status

Completed36
Terminated4
Recruiting2

Development Timeline

Analytics

Development Status

Total Trials
42
Active
2
Success Rate
90.0%
Most Advanced
Phase 4

Trials by Phase

Phase 13 (7.3%)
Phase 24 (9.8%)
Phase 318 (43.9%)
Phase 49 (22.0%)
N/A7 (17.1%)

Trials by Status

completed3686%
recruiting25%
terminated410%

Recent Activity

Clinical Trials (42)

Showing 20 of 42 trialsScroll for more
NCT07277907Phase 3

Efficacy and Safety of Lubiprostone in the Treatment of Slow Transit Constipation

Recruiting
NCT03720613

Risk of Major Adverse Cardiovascular Events for Naldemedine & Other Medications for Opioid Induced Constipation

Recruiting
NCT01839734Phase 2

Lubiprostone as a Modulator of Gut Microbial Translocation in HIV With Incomplete CD4 Recovery on Antiretroviral Therapy

Completed
NCT00908076Phase 4

Amitiza in Constipation Associated With PD (Parkinson's Disease)

Completed
NCT01096290Phase 4

Comparison of Lubiprostone and Placebo for the Relief of Constipation From Constipating Medications

Terminated
NCT00746395Phase 4

Randomized, Placebo-controlled Trial of Lubiprostone as a Preparation for Capsule Endoscopy

Completed
NCT02481947Phase 3

A Safety and Efficacy Evaluation of BLI400 Laxative in Constipated Adults

Completed
NCT02042183Phase 3

Lubiprostone in Children With Functional Constipation

Completed
NCT02766777Phase 3

Evaluation of the Safety of Lubiprostone in Pediatric Participants Aged ≥ 6 Years to < 18 Years With Functional Constipation

Completed
NCT01298219Phase 3

Opioid-induced Bowel Dysfunction (OBD) Pivotal Assessment of Lubiprostone (OPAL)

Completed
NCT02138136Phase 3

Lubiprostone for Children With Constipation

Completed
NCT03097861Phase 3

Evaluation of the Bioequivalence of Sprinkle and Capsule Formulations of Lubiprostone, as Compared to Placebo

Completed
NCT02544152Phase 2

Evaluation of the Efficacy and Safety of Lubiprostone in Adults With Mixed or Unsubtyped Irritable Bowel Syndrome

Terminated
NCT00452335Phase 4

Safety and Efficacy of Lubiprostone in Pediatric Patients With Constipation

Completed
NCT00399542Phase 3

Efficacy and Safety of Lubiprostone in Patients With Irritable Bowel Syndrome With Constipation

Completed
NCT00595946Phase 3

Opioid-induced Bowel Dysfunction: Pivotal Assessment of Lubiprostone

Completed
NCT01993875Phase 3

Pharmacodynamic, Pharmacokinetic, and Tolerability Study of a Liquid Form of Lubiprostone in Adult Subjects With Chronic Idiopathic Constipation

Completed
NCT00597428Phase 3

Opioid-induced Bowel Dysfunction Pivotal Assessment of Lubiprostone

Completed
NCT00380250Phase 3

Efficacy and Safety of Lubiprostone in Patients With Irritable Bowel Syndrome With Constipation

Completed
NCT02729909Phase 3

Lubiprostone for Chronic Idiopathic Constipation Treatment

Completed

Drug Details

Intervention Type
DRUG
Total Trials
42