LPS
LPS is a biological therapy with 16 clinical trials. Currently 2 active trials ongoing. Historical success rate of 83.3%.
Success Metrics
Based on 10 completed trials
Phase Distribution
Phase Distribution
8
Early Stage
0
Mid Stage
3
Late Stage
Highest Phase Reached
Phase 4Trial Status & Enrollment
76.9%
10 of 13 finished
23.1%
3 ended early
2
trials recruiting
16
all time
Detailed Status
Development Timeline
Analytics
Development Status
Trials by Phase
Trials by Status
Recent Activity
Neural Response to Inflammatory Challenge in Major Depressive Disorder
Immunomodulatory Effects of Dexamethasone, Tocilizumab and Anakinra During Experimental Human Endotoxemia
A Study Exploring the Use of Vaccine and Antigen Challenges for Immune Monitoring in Healthy Participants
Peripheral Benzodiazepine Receptors (PBR28) Brain PET Imaging With Lipopolysaccharide Challenge for the Study of Microglia Function in Alzheimer's Disease
Brain Biomarker on Inflammation Response
Clinical Trials (16)
Neural Response to Inflammatory Challenge in Major Depressive Disorder
Immunomodulatory Effects of Dexamethasone, Tocilizumab and Anakinra During Experimental Human Endotoxemia
A Study Exploring the Use of Vaccine and Antigen Challenges for Immune Monitoring in Healthy Participants
Peripheral Benzodiazepine Receptors (PBR28) Brain PET Imaging With Lipopolysaccharide Challenge for the Study of Microglia Function in Alzheimer's Disease
Brain Biomarker on Inflammation Response
The Effects of Human Endotoxemia on Functional Capacity of Hematopoietic Stem and Progenitor Cells
First-time-in-Human (FTIH) Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single (in Both Fed and Fasted States) or Repeat Doses of GSK3358699
Vorapaxar in the Human Endotoxemia Model
A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Doses of Inhaled GSK1995057
The Effects of Preceding LPS Administration on the Fluenz-induced Immune Response
A Study To Evaluate The Safety And Effects On The Body Of An Investigational Drug Using An Endotoxin-Induced Inflammatory Response Model
Whey Protein Study - Identification of Sustainable Satiety
A Study of Intracellular Signaling in Muscle and Fat Cells During Ketosis
The Effects of Oral Dipyridamole Treatment on the Innate Immune Response During Human Endotoxemia
Inflammatory Markers in Sputum After LPS Inhalation
Ethnic Differences in the Inflammatory Response in Systemic Inflammation
All 16 trials loaded
Drug Details
- Intervention Type
- BIOLOGICAL
- Total Trials
- 16