Success Metrics

Clinical Success Rate
75.5%

Based on 37 completed trials

Completion Rate
76%(37/49)
Active Trials
15(18%)
Results Posted
43%(16 trials)
Terminated
12(14%)

Phase Distribution

Ph phase_1
16
19%
Ph not_applicable
4
5%
Ph phase_3
21
25%
Ph early_phase_1
2
2%
Ph phase_2
38
46%

Phase Distribution

18

Early Stage

38

Mid Stage

21

Late Stage

Phase Distribution81 total trials
Early Phase 1First-in-human
2(2.5%)
Phase 1Safety & dosage
16(19.8%)
Phase 2Efficacy & side effects
38(46.9%)
Phase 3Large-scale testing
21(25.9%)
N/ANon-phased studies
4(4.9%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

68.5%

37 of 54 finished

Non-Completion Rate

31.5%

17 ended early

Currently Active

15

trials recruiting

Total Trials

83

all time

Status Distribution
Active(17)
Completed(37)
Terminated(17)
Other(12)

Detailed Status

Completed37
Terminated12
unknown11
Recruiting9
Active, not recruiting6
Withdrawn5

Development Timeline

Analytics

Development Status

Total Trials
83
Active
15
Success Rate
75.5%
Most Advanced
Phase 3

Trials by Phase

Early Phase 12 (2.5%)
Phase 116 (19.8%)
Phase 238 (46.9%)
Phase 321 (25.9%)
N/A4 (4.9%)

Trials by Status

not_yet_recruiting22%
terminated1214%
active_not_recruiting67%
withdrawn56%
suspended11%
unknown1113%
recruiting911%
completed3745%

Recent Activity

Clinical Trials (83)

Showing 20 of 83 trialsScroll for more
NCT06325683Phase 2

Anti-Lag-3 (Relatlimab) and Anti-PD-1 Blockade (Nivolumab) Versus Standard of Care (Lomustine) for the Treatment of Patients With Recurrent Glioblastoma

Suspended
NCT05902169Phase 3

Sonocloud-9 in Association With Carboplatin Versus Standard-of-Care Chemotherapies (CCNU or TMZ) in Recurrent GBM

Recruiting
NCT03970447Phase 2

A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma

Recruiting
NCT02724579Phase 2

Reduced Craniospinal Radiation Therapy and Chemotherapy in Treating Younger Patients With Newly Diagnosed WNT-Driven Medulloblastoma

Active Not Recruiting
NCT05382338Phase 3

A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss

Recruiting
NCT05326464Phase 3

Tofacitinib in Recurrent GBM Patients

Completed
NCT05095376Phase 3

Testing the Addition of the Chemotherapy Drug Lomustine (Gleostine) to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Methylated Glioblastoma

Active Not Recruiting
NCT00085735Phase 3

Comparison of Radiation Therapy Regimens in Combination With Chemotherapy in Treating Young Patients With Newly Diagnosed Standard-Risk Medulloblastoma

Completed
NCT07632209Phase 2

Lomustine Combined With Anlotinib as Interventional Therapy for Extensive-stage Small Cell Lung Cancer Resistant to Second-line and Above Treatment

Not Yet Recruiting
NCT05904119Phase 3

Lomustine With and Without Reirradiation for First Progression of Glioblastoma: a Randomized Phase III Study

Recruiting
NCT07629089Phase 1

VorAsidenib With Lomustine In Patients With rEcurrent IDH-mutaNT Glioma Harboring IDH1 and/or IDH2 Mutations

Not Yet Recruiting
NCT03382977Phase 1

Study to Evaluate Safety, Tolerability, and Optimal Dose of Candidate GBM Vaccine VBI-1901 in Recurrent GBM Subjects

Terminated
NCT06336291Phase 2

A Study With L19TNF in Combination With Lomustine in Patients With Glioblastoma at Progression or Recurrence

Active Not Recruiting
NCT04762069Phase 2

A Study of Berubicin in Adult Subjects With Recurrent Glioblastoma Multiforme

Active Not Recruiting
NCT06419946Phase 3

Lomustine in Addition to Standard of Care in Patients With MGMT Methylated Glioblastoma

Recruiting
NCT04049669Phase 2

Pediatric Trial of Indoximod With Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPG

Active Not Recruiting
NCT01582269Phase 2

A Study in Recurrent Glioblastoma (GB)

Completed
NCT04402073Phase 2

Personalized Risk-Adapted Therapy in Post-Pubertal Patients With Newly-Diagnosed Medulloblastoma

Terminated
NCT07145112Phase 1

Laser Interstitial Thermal Therapy (LITT) and Lomustine (CCNU) for Recurrent Glioblastoma

Recruiting
NCT04863950Phase 2

Investigator-Initiated Study of Imipramine Hydrochloride and Lomustine in Recurrent Glioblastoma

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
83