Success Metrics

Clinical Success Rate
85.7%

Based on 42 completed trials

Completion Rate
86%(42/49)
Active Trials
4(7%)
Results Posted
50%(21 trials)
Terminated
7(11%)

Phase Distribution

Ph phase_1
13
21%
Ph early_phase_1
1
2%
Ph not_applicable
3
5%
Ph phase_4
13
21%
Ph phase_2
19
31%
Ph phase_3
10
16%

Phase Distribution

14

Early Stage

19

Mid Stage

23

Late Stage

Phase Distribution59 total trials
Early Phase 1First-in-human
1(1.7%)
Phase 1Safety & dosage
13(22.0%)
Phase 2Efficacy & side effects
19(32.2%)
Phase 3Large-scale testing
10(16.9%)
Phase 4Post-market surveillance
13(22.0%)
N/ANon-phased studies
3(5.1%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

84.0%

42 of 50 finished

Non-Completion Rate

16.0%

8 ended early

Currently Active

4

trials recruiting

Total Trials

61

all time

Status Distribution
Active(4)
Completed(42)
Terminated(8)
Other(7)

Detailed Status

Completed42
Terminated7
unknown7
Recruiting4
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
61
Active
4
Success Rate
85.7%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (1.7%)
Phase 113 (22.0%)
Phase 219 (32.2%)
Phase 310 (16.9%)
Phase 413 (22.0%)
N/A3 (5.1%)

Trials by Status

recruiting47%
terminated711%
unknown711%
withdrawn12%
completed4269%

Recent Activity

Clinical Trials (61)

Showing 20 of 61 trialsScroll for more
NCT07540338Phase 1

A Study to Investigate Lithium Brain/Plasma Pharmacokinetics and Safety of an AL001 Oral Capsule Compared to a Marketed Immediate-release Lithium Carbonate Capsule in Subjects With Bipolar I Disorder

Recruiting
NCT06184581Phase 4

Lithium Versus Lamotrigine in Bipolar Disorder, Type II

Recruiting
NCT05814640Phase 1

Sequenced Treatment Alternatives to Relieve Adolescent Depression (STAR-AD)

Recruiting
NCT04623398Phase 3

Effect of Lithium in Patients With Autism Spectrum Disorder and Phelan-McDermid Syndrome (SHANK3 Haploinsufficiency)

Completed
NCT05126238Phase 3

A Lithium-Based Medication to Improve Neurological Outcomes After Surgical Carotid Reconstruction

Terminated
NCT03185208Phase 4

Lithium As a Treatment to Prevent Impairment of Cognition in Elders

Completed
NCT06719544Phase 1

A Study of Lithium and Enlicitide in Healthy Adult Participants (MK-0616-034)

Completed
NCT02862210Phase 2

Low-Dose Lithium for the Treatment of Behavioral Symptoms in Frontotemporal Dementia

Completed
NCT05402891Phase 2

The CHAMP-study: The CHemopreventive Effect of Lithium in Familial AdenoMatous Polyposis

Completed
NCT01565759Phase 1

In Vivo Lithium Treatment Effects on Gene Expression Levels in Lymphoblastoid Cell Lines From Human Healthy Subjects

Completed
NCT06424613

Effects of Lithium on Suicide Prevention in Adolescents and Young Adults With Bipolar Disorder in China

Recruiting
NCT02893371

Longitudinal Comparative Effectiveness of Bipolar Disorder Therapies

Terminated
NCT01112813Phase 3

The Neurotrophic Effects of Lithium Carbonate Following Stroke: A Feasibility Study

Completed
NCT02999022Phase 2

Lithium for Fracture Treatment: a Double Blind Randomized Controlled Trial (LiFT)

Unknown
NCT05221593Phase 3

Efficacy of Lithium Against Chemotherapy Induced Neutropenia in Breast Cancer Patients

Completed
NCT04222816Phase 4

Effect of Regulated Add -on Sodium Chloride Intake on Stabilization of Serum Lithium Concentration in Bipolar Disorder

Completed
NCT02601859Not Applicable

Evaluation of Lithium as a Glycogen-Synthase-Kinase-3 (GSK-3) Inhibitor in Mild Cognitive Impairment

Completed
NCT02918097Phase 4

Cost- Effectiveness and Quality of Life Assessment in Bipolar Disorder Depressive Episode

Completed
NCT00790582Phase 2

A Multi-Center Controlled Screening Trial of Safety and Efficacy of Lithium Carbonate in Subjects With Amyotrophic Lateral Sclerosis (ALS)

Completed
NCT00683943Phase 1

Lithium Treatment for Patients With Spinocerebellar Ataxia Type I

Completed

Drug Details

Intervention Type
DRUG
Total Trials
61