Success Metrics

Clinical Success Rate
57.1%

Based on 4 completed trials

Completion Rate
57%(4/7)
Active Trials
14(61%)
Results Posted
150%(6 trials)
Terminated
3(13%)

Phase Distribution

Ph phase_1
9
39%
Ph phase_2
13
57%
Ph phase_3
1
4%

Phase Distribution

9

Early Stage

13

Mid Stage

1

Late Stage

Phase Distribution23 total trials
Phase 1Safety & dosage
9(39.1%)
Phase 2Efficacy & side effects
13(56.5%)
Phase 3Large-scale testing
1(4.3%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

50.0%

4 of 8 finished

Non-Completion Rate

50.0%

4 ended early

Currently Active

14

trials recruiting

Total Trials

23

all time

Status Distribution
Active(15)
Completed(4)
Terminated(4)

Detailed Status

Recruiting9
Active, not recruiting5
Completed4
Terminated3
Not yet recruiting1
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
23
Active
14
Success Rate
57.1%
Most Advanced
Phase 3

Trials by Phase

Phase 19 (39.1%)
Phase 213 (56.5%)
Phase 31 (4.3%)

Trials by Status

completed417%
recruiting939%
terminated313%
not_yet_recruiting14%
withdrawn14%
active_not_recruiting522%

Recent Activity

Clinical Trials (23)

Showing 20 of 23 trialsScroll for more
NCT05564390Phase 2

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Recruiting
NCT05554406Phase 2

Testing the Effects of Novel Therapeutics for Newly Diagnosed, Untreated Patients With High-Risk Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)

Recruiting
NCT04293562Phase 3

A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

Recruiting
NCT03878199Phase 1

Testing the Effect of Taking Ruxolitinib and CPX-351 in Combination for the Treatment of Advanced Phase Myeloproliferative Neoplasms

Terminated
NCT04128748Phase 1

Liposomal Cytarabine and Daunorubicin (CPX-351) and Quizartinib for the Treatment of Acute Myeloid Leukemia and High Risk Myelodysplastic Syndrome

Recruiting
NCT03896269Phase 1

CPX-351 in Treating Patients With Relapsed or Refractory High Risk Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia

Recruiting
NCT05554419Phase 2

Testing the Use of Combination Therapy in Patients With Persistent Low Level Acute Myeloid Leukemia Following Initial Treatment, The ERASE Study (A MyeloMATCH Treatment Trial)

Not Yet Recruiting
NCT04049539Phase 1

Vyxeos for Re-induction Treatment of Acute Myeloid Leukemia Patients With Persistent Disease After Induction

Recruiting
NCT05627232Phase 1

Tazemetostat and Palbociclib With CPX-351for R/R AML

Recruiting
NCT03226418Phase 2

Geriatric Assessment & Genetic Profiling to Personalize Therapy in Older Adults With Acute Myeloid Leukemia

Completed
NCT02286726Phase 2

CPX-351 in Treating Patients With Newly Diagnosed, High-Risk Acute Myeloid Leukemia

Completed
NCT03672539Phase 2

Liposome-encapsulated Daunorubicin-Cytarabine and Gemtuzumab Ozogamicin in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) or High Risk Myelodysplastic Syndrome

Active Not Recruiting
NCT03629171Phase 2

Liposome-encapsulated Daunorubicin-Cytarabine and Venetoclax in Treating Participants With Relapsed, Refractory or Untreated Acute Myeloid Leukemia

Recruiting
NCT04915612Phase 1

Liposomal Cytarabine, Daunorubicin, and Gemtuzumab Ozogamicin for the Treatment of Relapsed Refractory Pediatric Patients With Acute Myeloid Leukemia

Completed
NCT04269213Phase 2

CPX-351 for the Treatment of Secondary Acute Myeloid Leukemia in Patients Younger Than 60 Years Old

Active Not Recruiting
NCT04802161Phase 2

Comparing the Addition of an Anti-Cancer Drug, Pomalidomide, to the Usual Chemotherapy Treatment (Daunorubicin and Cytarabine Liposome) in Newly Diagnosed Acute Myeloid Leukemia With Myelodysplastic Syndrome-Related Changes

Active Not Recruiting
NCT04493164Phase 2

CPX-351 and Ivosidenib for the Treatment of IDH1 Mutated Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Recruiting
NCT04195945Phase 2

CPX-351 or CLAG-M Regimen for the Treatment of Acute Myeloid Leukemia or Other High-Grade Myeloid Neoplasms in Medically Less-Fit Patients

Active Not Recruiting
NCT04526288Phase 2

CPX-351 Versus Immediate Stem Cell Transplantation for the Treatment of High-Grade Myeloid Cancers With Measurable Residual Disease

Terminated
NCT03904251Phase 1

CPX-351 and Gemtuzumab Ozogamicin in Treating Patients With Relapsed Acute Myeloid Leukemia

Terminated

Drug Details

Intervention Type
DRUG
Total Trials
23