Success Metrics

Clinical Success Rate
100.0%

Based on 11 completed trials

Completion Rate
100%(11/11)
Active Trials
20(56%)
Results Posted
82%(9 trials)

Phase Distribution

Ph phase_2
10
28%
Ph phase_4
6
17%
Ph phase_1
3
8%
Ph not_applicable
4
11%
Ph phase_3
9
25%

Phase Distribution

3

Early Stage

10

Mid Stage

15

Late Stage

Phase Distribution32 total trials
Phase 1Safety & dosage
3(9.4%)
Phase 2Efficacy & side effects
10(31.3%)
Phase 3Large-scale testing
9(28.1%)
Phase 4Post-market surveillance
6(18.8%)
N/ANon-phased studies
4(12.5%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

100.0%

11 of 11 finished

Non-Completion Rate

0.0%

0 ended early

Currently Active

20

trials recruiting

Total Trials

36

all time

Status Distribution
Active(22)
Completed(11)
Other(3)

Detailed Status

Recruiting18
Completed11
unknown3
Active, not recruiting2
Not yet recruiting2

Development Timeline

Analytics

Development Status

Total Trials
36
Active
20
Success Rate
100.0%
Most Advanced
Phase 4

Trials by Phase

Phase 13 (9.4%)
Phase 210 (31.3%)
Phase 39 (28.1%)
Phase 46 (18.8%)
N/A4 (12.5%)

Trials by Status

active_not_recruiting26%
not_yet_recruiting26%
unknown38%
completed1131%
recruiting1850%

Recent Activity

Clinical Trials (36)

Showing 20 of 36 trialsScroll for more
NCT07571135Phase 4

Letermovir vs Valganciclovir in CMV R+ Kidney Transplant

Not Yet Recruiting
NCT05711667Phase 3

A Study of the Drug Letermovir as Prevention of Cytomegalovirus Infection After Stem Cell Transplant in Pediatric Patients

Recruiting
NCT06118515Phase 1

A Safety Assessment of Oral Letermovir in Infants With Symptomatic Congenital Cytomegalovirus

Recruiting
NCT07199465Phase 1

A Clinical Study of Letermovir (MK-8228) in Children and Adolescents Who Receive a Kidney Transplant (KT) (MK-8228-077)

Recruiting
NCT05041426Phase 2

Letermovir for CMV Prevention After Lung Transplantation

Completed
NCT05446571Phase 3

Prenatal Treatment of Congenital Cytomegalovirus Infection With Letermovir Versus Valaciclovir

Recruiting
NCT04732260Not Applicable

Prenatal Treatment of Congenital Cytomegalovirus Infection With Letermovir Randomized Against Valaciclovir - CYMEVALIII STEP1

Completed
NCT07020533Phase 1

A Vaccine (CMV-MVA Triplex Vaccine) for the Enhancement of CMV-Specific Immunity and the Prevention of CMV Viremia in Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplant

Recruiting
NCT07488728Not Applicable

Letermovir Prophylaxis in Children With EBV-Positive T/NK-Cell Lymphoproliferative Disease and Refractory/Relapsed EBV-Associated Hemophagocytic Lymphohistiocytosis

Recruiting
NCT07235683Phase 4

Combination Letermovir and Standard of Care Antiviral for Enhanced Antiviral Response in Cytomegalovirus Infection in Lung Transplant Recipients

Recruiting
NCT06575374Phase 2

Single Arm Pilot Trial of Letermovir for CMV Prophy in CAR T Cell

Recruiting
NCT06334497Phase 3

Letermovir-based Dual Therapy for Treatment of Cytomegalovirus Infections

Recruiting
NCT06449586Phase 3

CMV-specific T Cell Immunity Test Indicated Prophylaxis of Letermovir After All-HSCT

Active Not Recruiting
NCT07266467Phase 4

Efficacy and Safety of Leymovir Versus Valganciclovir in Prevention of Cytomegalovirus Infection and Cytomegalovirus Disease in Chinese Kidney Transplant Recipients

Recruiting
NCT06920251Phase 2

Phase II Trials of Letermovir Prophylaxis in Patients With RRMM Undergoing Elranatamab Therapy

Recruiting
NCT04060277Phase 2

Triplex Vaccine in Preventing CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplantation

Active Not Recruiting
NCT06639854Not Applicable

The Use of Cytomegalovirus Cell Mediated Immunity to Optimize the Duration of Letermovir Prophylaxis in Hematopoietic Cell Transplant Recipients

Recruiting
NCT06407232Phase 3

Letermovir (Prevymis) for CMV in Kidney and Pancreas Transplant Recipients

Recruiting
NCT07079735Phase 2

Valganciclovir vs. Letermovir for CMV Prophylaxis in Heart Transplant

Recruiting
NCT05362916Not Applicable

Letermovir in ART-treated HIV-infected Persons

Completed

Drug Details

Intervention Type
DRUG
Total Trials
36