Success Metrics

Clinical Success Rate

75.0%

Based on 3 completed trials

Completion Rate

75%(3/4)

Active Trials

1(20%)

Results Posted

133%(4 trials)

Terminated

1(20%)

Phase Distribution

Ph phase_1

20%

Ph phase_2

80%

Phase Distribution

Early Stage

Mid Stage

Late Stage

Phase Distribution5 total trials

Phase 1Safety & dosage

1(20.0%)

Phase 2Efficacy & side effects

4(80.0%)

Highest Phase Reached

Phase 2

Trial Status & Enrollment

Completion Rate

75.0%

3 of 4 finished

Non-Completion Rate

25.0%

1 ended early

Currently Active

trials recruiting

Total Trials

all time

Status Distribution

Active(1)

Completed(3)

Terminated(1)

Detailed Status

Completed3

Recruiting1

Terminated1

Development Timeline

Analytics

Development Status

Total Trials

Active

Success Rate

75.0%

Most Advanced

Phase 2

Trials by Phase

Phase 11 (20.0%)

Phase 24 (80.0%)

Trials by Status

recruiting120%

terminated120%

completed360%

Recent Activity

1 active trials

Showing 5 of 5

completedphase_2

LUMINOS-102: Lerapolturev With or Without Immune Checkpoint Blockade in Advanced PD-1 Refractory Melanoma

NCT04577807

recruitingphase_2

Lerapolturev (PVSRIPO) in GBM

NCT06177964

completedphase_2

Lerapolturev in Recurrent Malignant Glioma

NCT02986178

completedphase_2

LUMINOS-101: Lerapolturev (PVSRIPO) and Pembrolizumab in Patients With Recurrent Glioblastoma

NCT04479241

terminatedphase_1

LUMINOS-103: A Basket Trial of Safety & Efficacy of Lerapolturev With or Without Checkpoint Inhibitors

NCT04690699

Clinical Trials (5)

Showing 5 of 5 trials

NCT04577807Phase 2

LUMINOS-102: Lerapolturev With or Without Immune Checkpoint Blockade in Advanced PD-1 Refractory Melanoma

Completed

NCT06177964Phase 2

Lerapolturev (PVSRIPO) in GBM

Recruiting

NCT02986178Phase 2

Lerapolturev in Recurrent Malignant Glioma

Completed

NCT04479241Phase 2

LUMINOS-101: Lerapolturev (PVSRIPO) and Pembrolizumab in Patients With Recurrent Glioblastoma

Completed

NCT04690699Phase 1

LUMINOS-103: A Basket Trial of Safety & Efficacy of Lerapolturev With or Without Checkpoint Inhibitors

Terminated

All 5 trials loaded

Drug Details

Intervention Type: DRUG
Total Trials: 5