Success Metrics

Clinical Success Rate
75.8%

Based on 370 completed trials

Completion Rate
76%(370/488)
Active Trials
228(28%)
Results Posted
85%(314 trials)
Terminated
118(14%)

Phase Distribution

Ph phase_2
377
45%
Ph early_phase_1
7
1%
Ph phase_1
292
35%
Ph not_applicable
9
1%
Ph phase_3
119
14%
Ph phase_4
11
1%

Phase Distribution

299

Early Stage

377

Mid Stage

130

Late Stage

Phase Distribution815 total trials
Early Phase 1First-in-human
7(0.9%)
Phase 1Safety & dosage
292(35.8%)
Phase 2Efficacy & side effects
377(46.3%)
Phase 3Large-scale testing
119(14.6%)
Phase 4Post-market surveillance
11(1.3%)
N/ANon-phased studies
9(1.1%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

71.0%

370 of 521 finished

Non-Completion Rate

29.0%

151 ended early

Currently Active

228

trials recruiting

Total Trials

829

all time

Status Distribution
Active(249)
Completed(370)
Terminated(151)
Other(59)

Detailed Status

Completed370
Active, not recruiting131
Terminated118
Recruiting97
unknown57
Withdrawn33

Development Timeline

Analytics

Development Status

Total Trials
829
Active
228
Success Rate
75.8%
Most Advanced
Phase 4

Trials by Phase

Early Phase 17 (0.9%)
Phase 1292 (35.8%)
Phase 2377 (46.3%)
Phase 3119 (14.6%)
Phase 411 (1.3%)
N/A9 (1.1%)

Trials by Status

withdrawn334%
completed37045%
not_yet_recruiting182%
active_not_recruiting13116%
unknown577%
enrolling_by_invitation30%
recruiting9712%
terminated11814%
suspended20%

Recent Activity

Clinical Trials (829)

Showing 20 of 829 trialsScroll for more
NCT02232516Phase 2

Romidepsin and Lenalidomide in Treating Patients With Previously Untreated Peripheral T-Cell Lymphoma

Completed
NCT01352962Phase 1

Gemcitabine, Carboplatin, and Lenalidomide for Treatment of Advanced/Metastatic Urothelial Cancer and Other Solid Tumors

Completed
NCT00644228Phase 3

Lenalidomide and Dexamethasone With or Without Bortezomib in Treating Patients With Previously Untreated Multiple Myeloma

Active Not Recruiting
NCT00602641Phase 3

Melphalan, Prednisone, and Thalidomide or Lenalidomide in Treating Patients With Newly Diagnosed Multiple Myeloma

Active Not Recruiting
NCT07095452Phase 2

A Study to Assess A Change in Disease Activity and Adverse Events of Intravenous Etentamig and Daratumumab (Etentamig+D) Compared to Daratumumab, Lenalidomide, and Dexamethasone (DRd) in Adult Participants With Newly Diagnosed Multiple Myeloma Not Eligible for Transplant

Recruiting
NCT07639138Phase 2

Lenalidomide Plus Targeted Therapy and Immunotherapy for Refractory HCC

Recruiting
NCT05100862Phase 3

A Study of Zanubrutinib Plus Anti-CD20 Versus Lenalidomide Plus Rituximab in Participants With Relapsed/Refractory Follicular or Marginal Zone Lymphoma

Recruiting
NCT05561387Phase 3

Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment

Recruiting
NCT06348147Phase 2

Dara-RVd Induction for Newly Diagnosed Multiple Myeloma With Autologous Stem Cell Transplantation

Withdrawn
NCT05623020Phase 3

A Study to Learn About the Effects of the Combination of Elranatamab, Daratumumab and Lenalidomide Compared With Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma Who Are Not Candidates for Transplant

Recruiting
NCT07018050Phase 2

Phase II Study of QLS32015 Combination Therapy in the Treatment of Multiple Myeloma

Recruiting
NCT05776979Phase 2

Post-Transplant Maintenance Therapy With Isatuximab Plus Lenalidomide for High-Risk Multiple Myeloma Patients

Recruiting
NCT04923893Phase 3

A Study of Bortezomib, Lenalidomide and Dexamethasone (VRd) Followed by Cilta-cel, a CAR-T Therapy Directed Against BCMA Versus VRd Followed by Lenalidomide and Dexamethasone (Rd) Therapy in Participants With Newly Diagnosed Multiple Myeloma for Whom ASCT is Not Planned as Initial Therapy

Active Not Recruiting
NCT04722146Phase 1

A Study of Teclistamab With Other Anticancer Therapies in Participants With Multiple Myeloma

Active Not Recruiting
NCT04133636Phase 2

A Study of JNJ-68284528, a Chimeric Antigen Receptor T Cell (CAR-T) Therapy Directed Against B-cell Maturation Antigen (BCMA) in Participants With Multiple Myeloma

Active Not Recruiting
NCT06284122Phase 3

Study of Mosunetuzumab Plus Lenalidomide Compared to Anti-CD20 Anti-body + Chemotherapy in Follicular Lymphoma FLIPI2-5

Recruiting
NCT01702831Phase 2

Busulfan & Melphalan Conditioning for Autologous Stem Cell Transplant (ASCT) and Lenalidomide Maintenance

Completed
NCT05438043Phase 3

A Study of Daratumumab

Recruiting
NCT05050097Phase 1

A Study of Talquetamab With Other Anticancer Therapies in Participants With Multiple Myeloma

Active Not Recruiting
NCT06577025Phase 2

A Study of Different Sequences of Cilta-cel, Talquetamab in Combination With Daratumumab and Teclistamab in Combination With Daratumumab Following Induction With Daratumumab, Bortezomib, Lenalidomide and Dexamethasone in Participants With Standard-risk Newly Diagnosed Multiple Myeloma

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
829