Success Metrics

Clinical Success Rate
85.0%

Based on 384 completed trials

Completion Rate
85%(384/452)
Active Trials
73(11%)
Results Posted
46%(177 trials)
Terminated
68(10%)

Phase Distribution

Ph phase_1
88
13%
Ph phase_2
132
19%
Ph early_phase_1
32
5%
Ph not_applicable
147
22%
Ph phase_4
194
28%
Ph phase_3
57
8%

Phase Distribution

120

Early Stage

132

Mid Stage

251

Late Stage

Phase Distribution650 total trials
Early Phase 1First-in-human
32(4.9%)
Phase 1Safety & dosage
88(13.5%)
Phase 2Efficacy & side effects
132(20.3%)
Phase 3Large-scale testing
57(8.8%)
Phase 4Post-market surveillance
194(29.8%)
N/ANon-phased studies
147(22.6%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

77.7%

384 of 494 finished

Non-Completion Rate

22.3%

110 ended early

Currently Active

73

trials recruiting

Total Trials

683

all time

Status Distribution
Active(93)
Completed(384)
Terminated(110)
Other(96)

Detailed Status

Completed384
unknown91
Terminated68
Recruiting59
Withdrawn42
Not yet recruiting17

Development Timeline

Analytics

Development Status

Total Trials
683
Active
73
Success Rate
85.0%
Most Advanced
Phase 4

Trials by Phase

Early Phase 132 (4.9%)
Phase 188 (13.5%)
Phase 2132 (20.3%)
Phase 357 (8.8%)
Phase 4194 (29.8%)
N/A147 (22.6%)

Trials by Status

active_not_recruiting142%
suspended51%
unknown9113%
not_yet_recruiting172%
completed38456%
terminated6810%
withdrawn426%
recruiting599%
enrolling_by_invitation30%

Recent Activity

Clinical Trials (683)

Showing 20 of 683 trialsScroll for more
NCT04781673Phase 4

Ketamine vs Lidocaine in Traumatic Rib Fractures

Active Not Recruiting
NCT03090776Early Phase 1

Prevention of Post Mastectomy With Intraoperative Ketamine

Completed
NCT04560660Phase 2

Ketamine-enhanced Prolonged Exposure Therapy in PTSD

Completed
NCT07705022Phase 2

Assessing Covert Consciousness During Dexmedetomidine and Ketamine Sedation: An fMRI Study

Not Yet Recruiting
NCT05756621

Dual Anti-glutamate Therapy in Super-refractory Status Epilepticus After Cardiac Arrest

Completed
NCT05268562Phase 4

Ketamine and Kidney Injury in Cardiac Surgery

Active Not Recruiting
NCT05401227Phase 1

Glutamatergic Mechanisms: Aim2

Recruiting
NCT05229055Phase 2

Intranasal Ketamine Versus Subcutaneous Ketamine for Treatment of Post-traumatic Acute Pain in the Emergency Department ( INVESCK )

Completed
NCT06480201Phase 1

Gamma Oscillations as a Prognostic Marker for Ketamine Therapy in Treatment Resistant Depression

Recruiting
NCT07680140Phase 4

Biomarker-Guided Antidepressant Selection

Not Yet Recruiting
NCT03573349Early Phase 1

Ketamine Associated ACC GABA and Glutamate Change and Depression Remission:

Active Not Recruiting
NCT07676955Phase 4

Dexmedetomidine Versus Ketamine Loading for Dexmedetomidine Sedation During Elective Cesarean Section Under Spinal Anesthesia

Completed
NCT07670052Phase 4

Intraperitoneal Ketamine Versus Fentanyl as Adjuvants to Bupivacaine in Laparoscopic Cholecystectomy

Not Yet Recruiting
NCT06986109Not Applicable

Effect of Subanaesthetic Dose of Ketamine on Depth of Anaesthesia Consistency

Completed
NCT03065335Phase 1

Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated-Dosed Ketamine Infusions in Major Depressive Disorder

Recruiting
NCT05597878Phase 2

Opioid-Free Pain Control Regimen Following Robotic Radical Prostatectomy

Terminated
NCT07640243Not Applicable

Sedation Methods in Percutaneous Transhepatic Biliary Drainage: Procedure Quality and Recovery

Recruiting
NCT05306899Phase 3

Multi-center RCT of IV Ketamine Efficacy and Safety in Chronic Daily Headaches

Recruiting
NCT02734602Not Applicable

Imaging SV2A in Mood Disorders

Active Not Recruiting
NCT06538285Phase 2

Ketamine-Assisted Recovery for Methamphetamine Use Disorder & HIV

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
683