Success Metrics

Clinical Success Rate
92.3%

Based on 12 completed trials

Completion Rate
92%(12/13)
Active Trials
0(0%)
Results Posted
67%(8 trials)
Terminated
1(8%)

Phase Distribution

Ph phase_2
8
62%
Ph phase_1
5
38%

Phase Distribution

5

Early Stage

8

Mid Stage

0

Late Stage

Phase Distribution13 total trials
Phase 1Safety & dosage
5(38.5%)
Phase 2Efficacy & side effects
8(61.5%)

Highest Phase Reached

Phase 2

Trial Status & Enrollment

Completion Rate

92.3%

12 of 13 finished

Non-Completion Rate

7.7%

1 ended early

Currently Active

0

trials recruiting

Total Trials

13

all time

Status Distribution
Completed(12)
Terminated(1)

Detailed Status

Completed12
Terminated1

Development Timeline

Analytics

Development Status

Total Trials
13
Active
0
Success Rate
92.3%
Most Advanced
Phase 2

Trials by Phase

Phase 15 (38.5%)
Phase 28 (61.5%)

Trials by Status

terminated18%
completed1292%

Recent Activity

Clinical Trials (13)

Showing 13 of 13 trials
NCT04439539Phase 2

A Study of JNJ-73763989, Pegylated Interferon Alpha-2a, Nucleos(t)Ide Analog (NA) With or Without JNJ-56136379 in Treatment-naive Participants With Hepatitis B e Antigen (HBeAg) Positive Chronic Hepatitis B Virus (HBV) Infection

Completed
NCT05123599Phase 1

A Study of JNJ-73763989, JNJ-64300535, and Nucleos(t)Ide Analogs in Virologically Suppressed, Hepatitis B e Antigen (HBeAg)- Negative Participants With Chronic Hepatitis B Virus Infection

Completed
NCT04585789Phase 2

A Study to Assess Intrahepatic and Peripheral Changes of Immunologic and Virologic Markers in Chronic Hepatitis B Virus Infection

Completed
NCT05275023Phase 2

An Efficacy and Safety Study of a Combination of JNJ-73763989, Nucleos(t)Ide Analogs (NA), and a Programmed Cell Death Protein Receptor-1 (PD-1) Inhibitor in Chronic Hepatitis B Participants

Completed
NCT04535544Phase 2

A Study of JNJ-73763989 + Nucleos(t)Ide Analog in Participants Co-Infected With Hepatitis B and Hepatitis D Virus

Completed
NCT03982186Phase 2

A Study of Different Combination Regimens Including JNJ-73763989 and/or JNJ-56136379 for the Treatment of Chronic Hepatitis B Virus Infection

Completed
NCT04129554Phase 2

A Study of JNJ 73763989+JNJ 56136379+Nucleos(t)Ide Analog (NA) Regimen Compared to NA Alone in e Antigen Negative Virologically Suppressed Participants With Chronic Hepatitis B Virus Infection

Completed
NCT04002752Phase 1

A Study of JNJ-73763989 in Healthy Japanese Adult Participants

Completed
NCT04667104Phase 2

A Study of JNJ-73763989, JNJ-56136379, Nucleos(t)Ide Analogs, and Pegylated Interferon Alpha-2a in Virologically Suppressed Participants With Chronic Hepatitis B Virus Infection

Completed
NCT05005507Phase 2

A Study of JNJ-73763989, Pegylated Interferon Alpha-2a and Nucleos(t)Ide Analogs in Participants With Chronic Hepatitis B Virus Infection

Terminated
NCT04963738Phase 1

A Study of JNJ-73763989 in Adult Participants With Renal Impairment

Completed
NCT04586439Phase 1

A Study of JNJ-73763989 in Healthy Chinese Adult Participants

Completed
NCT04208386Phase 1

A Study to Evaluate the Effect of Hepatic Impairment on JNJ-73763989

Completed

All 13 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
13