Success Metrics

Clinical Success Rate
62.5%

Based on 5 completed trials

Completion Rate
63%(5/8)
Active Trials
0(0%)
Results Posted
20%(1 trials)
Terminated
3(33%)

Phase Distribution

Ph phase_1
6
67%
Ph phase_2
2
22%

Phase Distribution

6

Early Stage

2

Mid Stage

0

Late Stage

Phase Distribution8 total trials
Phase 1Safety & dosage
6(75.0%)
Phase 2Efficacy & side effects
2(25.0%)

Highest Phase Reached

Phase 2

Trial Status & Enrollment

Completion Rate

62.5%

5 of 8 finished

Non-Completion Rate

37.5%

3 ended early

Currently Active

0

trials recruiting

Total Trials

9

all time

Status Distribution
Completed(5)
Terminated(3)
Other(1)

Detailed Status

Completed5
Terminated3
unknown1

Development Timeline

Analytics

Development Status

Total Trials
9
Active
0
Success Rate
62.5%
Most Advanced
Phase 2

Trials by Phase

Phase 16 (75.0%)
Phase 22 (25.0%)

Trials by Status

completed556%
terminated333%
unknown111%

Recent Activity

Clinical Trials (9)

Showing 9 of 9 trials
NCT03656510Phase 2

Study to Evaluate Safety and Antiviral Activity of Doses of JNJ-53718678 in Children (>=28 Days to <=3 Years) With Respiratory Syncytial Virus Infection

Terminated
NCT02729467Phase 1

A Study to Assess the Effects of Itraconazole and Rifampicin on the Single-Dose Pharmacokinetics of JNJ-53718678 in Healthy Adults

Completed
NCT04090086Phase 1

A Study to Assess Interaction Between JNJ-64417184 and JNJ-53718678 After Single and Multiple Dosing in Healthy Participants

Completed
NCT02387606Phase 2

Study to Evaluate Antiviral Activity, Safety, and Pharmacokinetics of Repeated Doses of Orally Administered JNJ 53718678 Against Respiratory Syncytial Virus Infection.

Completed
NCT04221412

Pre-Approval Access to JNJ-53718678 for the Treatment of Respiratory Syncytial Virus (RSV) Infection in (a) Immunocompromised Adult and Pediatric Participants

Unknown
NCT04332523Phase 1

A Study of JNJ-53718678 in Participants With Hepatic Impairment

Terminated
NCT02945007Phase 1

A Study to Assess the Relative Oral Bioavailability of a Single Dose of JNJ-53718678 Administered as Oral Concept Formulation Compared to the Current Oral Solution and to Assess the Effect of Food on the Pharmacokinetics of Oral Concept Formulation

Completed
NCT02593851Phase 1

A Study to Assess the Pharmacokinetics, Safety, and Tolerability of Multiple Doses of Orally Administered JNJ-53718678 in Infants Hospitalized With Respiratory Syncytial Virus (RSV) Infection

Terminated
NCT03002779Phase 1

A Study to Characterize the Absorption, Metabolism, and Excretion of 14C-JNJ-53718678 After a Single Oral Dose in Healthy Male Participants

Completed

All 9 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
9