Success Metrics

Active Trials
32(68%)

Phase Distribution

Ph phase_1
11
23%
Ph phase_2
35
74%

Phase Distribution

11

Early Stage

35

Mid Stage

0

Late Stage

Phase Distribution46 total trials
Phase 1Safety & dosage
11(23.9%)
Phase 2Efficacy & side effects
35(76.1%)

Highest Phase Reached

Phase 2

Trial Status & Enrollment

Completion Rate

0.0%

0 of 1 finished

Non-Completion Rate

100.0%

1 ended early

Currently Active

32

trials recruiting

Total Trials

47

all time

Status Distribution
Active(46)
Terminated(1)

Detailed Status

Recruiting31
Not yet recruiting14
Active, not recruiting1
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
47
Active
32
Success Rate
N/A
Most Advanced
Phase 2

Trials by Phase

Phase 111 (23.9%)
Phase 235 (76.1%)

Trials by Status

active_not_recruiting12%
recruiting3166%
withdrawn12%
not_yet_recruiting1430%

Recent Activity

Clinical Trials (47)

Showing 20 of 47 trialsScroll for more
NCT07397338Phase 1

Study of RAS(ON) Inhibitors in Combination With Ivonescimab in Patients With Solid Tumors

Recruiting
NCT06959550Phase 2

Phase II Study of Anti-PD-1/VEGF Bispecific Antibody Ivonescimab in Patients With Previously Treated Metastatic Colorectal Cancer

Recruiting
NCT07560124Phase 1

A Study of AK138D1 Alone or in Combination With Ivonescimab in Advanced Breast Cancer

Not Yet Recruiting
NCT06846346Phase 2

Testing Ivonescimab in Combination With Chemotherapy in Advanced or Metastatic Gastric/Gastroesophageal Adenocarcinoma

Recruiting
NCT06844422Phase 1

Adapted Guided Stereotactic Body Radiotherapy Combined With Chemotherapy and Enhancement of Novel Drug Ivonescimab for Pancreatic Cancer (ASCEND)

Recruiting
NCT07535437Phase 1

A Study of Ivonescimab in Combination With Dato-DXd or Osimertinib in People With Non-Small Cell Lung Cancer

Recruiting
NCT06567314Phase 2

Phase 2 Study of Ivonescimab in Patients With Cutaneous Squamous Cell Carcinoma

Recruiting
NCT07535463Phase 1

A Study of Ivonescimab, Chemotherapy, and Stereotactic Radiosurgery for People With Non-Small Cell Lung Cancer

Recruiting
NCT07516925Phase 2

A Study of Ivonescimab in People With Leiomyosarcoma

Recruiting
NCT07017673Phase 2

Phase II Trial of Ivonescimab in Combination With Carboplatin + Docetaxel in Patients With Early-Stage Triple Negative Breast Cancer

Recruiting
NCT06868732Phase 1

Evaluation of JSKN016 Combination Therapy in Subjects With NSCLC

Recruiting
NCT06925724Phase 2

A Study of Ivonescimab in People With Endometrial and Cervical Cancers

Recruiting
NCT06840834Phase 2

Evaluating Ivonescimab as a Potential Treatment for Pleural Mesothelioma Patients Whose Cancer Has Returned After Previous Immunotherapy and Chemotherapy

Recruiting
NCT07472478Phase 2

Phase II Neoadjuvant Study of Garsorasib Followed by Ivonescimab Plus Chemotherapy in Resectable Stage IIA-IIIB KRAS G12C-Mutant NSCLC (GIVEN Study)

Not Yet Recruiting
NCT07359040

Mechanism of Enhanced Efficacy of Ivonescimab in Neoadjuvant Therapy for Non-Small Cell Lung Cancer

Active Not Recruiting
NCT06951646Phase 2

ctDNA-MRD Guided Escalation of Ivonescimab and Docetaxel in Advanced NSCLC With Long-Term Responses to First-line Immunotherapy (CR1STAL-Adaptive)

Recruiting
NCT07070466Phase 2

Ivonescimab in Comb. With FOLFOX in Advanced HER2 Neg. GEA

Recruiting
NCT06940518Phase 2

Phase II Trial of Ivonescimab in Previously Treated Patients With Advanced Clear Cell Renal Cell Carcinoma

Recruiting
NCT06672575Phase 1

A Phase I/II Study of IVONESCIMAB in Recurrent Glioblastoma

Recruiting
NCT07405190Phase 2

Ivonescimab Alone And With Carboplatin/Pemetrexed For NSCLC

Not Yet Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
47