Success Metrics

Clinical Success Rate
93.8%

Based on 272 completed trials

Completion Rate
94%(272/290)
Active Trials
30(9%)
Results Posted
27%(74 trials)
Terminated
18(5%)

Phase Distribution

Ph early_phase_1
6
2%
Ph not_applicable
12
4%
Ph phase_2
20
6%
Ph phase_1
283
83%
Ph phase_3
6
2%
Ph phase_4
11
3%

Phase Distribution

289

Early Stage

20

Mid Stage

17

Late Stage

Phase Distribution338 total trials
Early Phase 1First-in-human
6(1.8%)
Phase 1Safety & dosage
283(83.7%)
Phase 2Efficacy & side effects
20(5.9%)
Phase 3Large-scale testing
6(1.8%)
Phase 4Post-market surveillance
11(3.3%)
N/ANon-phased studies
12(3.6%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

92.2%

272 of 295 finished

Non-Completion Rate

7.8%

23 ended early

Currently Active

30

trials recruiting

Total Trials

340

all time

Status Distribution
Active(38)
Completed(272)
Terminated(23)
Other(7)

Detailed Status

Completed272
Recruiting25
Terminated18
Not yet recruiting8
unknown7
Withdrawn5

Development Timeline

Analytics

Development Status

Total Trials
340
Active
30
Success Rate
93.8%
Most Advanced
Phase 4

Trials by Phase

Early Phase 16 (1.8%)
Phase 1283 (83.7%)
Phase 220 (5.9%)
Phase 36 (1.8%)
Phase 411 (3.3%)
N/A12 (3.6%)

Trials by Status

recruiting257%
unknown72%
terminated185%
not_yet_recruiting82%
withdrawn51%
active_not_recruiting51%
completed27280%

Recent Activity

30 active trials
Showing 5 of 340
recruitingphase_1

A Study of Mevrometostat for Treatment of Relapsed/Refractory SCLC, Castration Resistant Prostate Cancer, and Follicular Lymphoma

NCT03460977
recruitingphase_1

A Study of LY4515100 in Healthy Participants

NCT07339722
recruitingphase_2

Itraconazole in Combination With Ablation for the Prevention of Esophageal Cancer in Patients With High-risk Barrett's Esophagus

NCT06732388
recruitingphase_1

A Study to Evaluate How Multiple Doses of Itraconazole Interacts With Nacresertib in Healthy Adult Participants

NCT07649954
recruitingphase_1

A Clinical Study to Test if an Investigational Treatment Called BNT326 is Safe and Potentially Beneficial When Used Alone or in Combination With Other Investigational Treatments Such as BNT327, for People With Advanced Malignant Tumors

NCT07070232
View all 340 trials

Clinical Trials (340)

Showing 20 of 340 trialsScroll for more
NCT03460977Phase 1

A Study of Mevrometostat for Treatment of Relapsed/Refractory SCLC, Castration Resistant Prostate Cancer, and Follicular Lymphoma

Recruiting
NCT07339722Phase 1

A Study of LY4515100 in Healthy Participants

Recruiting
NCT06732388Phase 2

Itraconazole in Combination With Ablation for the Prevention of Esophageal Cancer in Patients With High-risk Barrett's Esophagus

Recruiting
NCT07649954Phase 1

A Study to Evaluate How Multiple Doses of Itraconazole Interacts With Nacresertib in Healthy Adult Participants

Recruiting
NCT07070232Phase 1

A Clinical Study to Test if an Investigational Treatment Called BNT326 is Safe and Potentially Beneficial When Used Alone or in Combination With Other Investigational Treatments Such as BNT327, for People With Advanced Malignant Tumors

Recruiting
NCT07590102Phase 1

A Study to Investigate the Effect of the CYP3A Inducer Phenytoin and the CYP3A Inhibitor Itraconazole on the Pharmacokinetics of BGB-58067 in Healthy Participants

Recruiting
NCT07242781Phase 1

A Study to Evaluate the Effect of Itraconazole and Rifampin on the Drug Levels of AR-LDD (BMS-986365) in Healthy Adult Male Participants

Terminated
NCT07402915Phase 1

Drug-drug Interaction Study With AZD5335 and Itraconazole in Participants With Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Recruiting
NCT07685600Phase 1

Investigating the Effect of Itraconazole on the Pharmacokinetics of AZD4144 in Healthy Participants

Not Yet Recruiting
NCT07308652Phase 1

A Study in Healthy Men to Test How Itraconazole Influences the Amount of BI 764198 in the Blood

Completed
NCT07661108Phase 1

A Clinical Study of MK-8527 in Healthy Participants (MK-8527-021)

Recruiting
NCT07548606Phase 1

A Drug-Drug Interaction Study of Itraconazole and Opevesostat (MK-5684) in Healthy Adult Male Participants (MK-5684-017)

Completed
NCT06400472Phase 1

A Study of LY4170156 in Participants With Selected Advanced Solid Tumors

Recruiting
NCT07592572Phase 1

A Study of the Effects of Itraconazole on LY4395089 in Healthy Participants

Recruiting
NCT07575945Phase 1

A Study to Learn if a Medicine Called Itraconazole Changes How the Body Processes the Study Medicine PF-08642534 in Healthy Adults.

Active Not Recruiting
NCT06909162Phase 1

A Study to Evaluate the Effect of Food on the Single-Dose Pharmacokinetics and a Drug-Drug Interaction Evaluation of Itraconazole and Carbamazepine on INCB123667 When Administered Orally to Healthy Adult Participants

Completed
NCT07542847Phase 1

A Study to Test the Effects of Itraconazole and Carbamazepine on OPC-167832 in Healthy Men and Women

Completed
NCT06710990Phase 1

Investigation of Drug-drug Interaction of Ritonavir and Itraconazole on the Pharmacokinetics of SHR-A1811 in Subjects With HER2-expressing Advanced Breast Cancer

Completed
NCT06041438Phase 1

A Study in Healthy Men to Test Whether Itraconazole Influences the Amount of BI 1584862 in the Blood

Completed
NCT07620041Phase 1

QLC5508 in Advanced Solid Tumors:: C-QTc, Pharmacokinetics (PK) Comparisons and Drug-drug Interaction

Not Yet Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
340