Success Metrics

Clinical Success Rate

88.9%

Based on 8 completed trials

Completion Rate

89%(8/9)

Active Trials

1(6%)

Results Posted

25%(2 trials)

Terminated

1(6%)

Phase Distribution

Ph early_phase_1

Ph phase_2

33%

Ph not_applicable

11%

Ph phase_3

17%

Ph phase_4

17%

Ph phase_1

17%

Phase Distribution

Early Stage

Mid Stage

Late Stage

Phase Distribution18 total trials

Early Phase 1First-in-human

1(5.6%)

Phase 1Safety & dosage

3(16.7%)

Phase 2Efficacy & side effects

6(33.3%)

Phase 3Large-scale testing

3(16.7%)

Phase 4Post-market surveillance

3(16.7%)

N/ANon-phased studies

2(11.1%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

66.7%

8 of 12 finished

Non-Completion Rate

33.3%

4 ended early

Currently Active

trials recruiting

Total Trials

all time

Status Distribution

Active(3)

Completed(8)

Terminated(4)

Other(3)

Detailed Status

Completed8

Withdrawn3

unknown3

Not yet recruiting2

Terminated1

Active, not recruiting1

Development Timeline

Analytics

Development Status

Total Trials

Active

Success Rate

88.9%

Most Advanced

Phase 4

Trials by Phase

Early Phase 11 (5.6%)

Phase 13 (16.7%)

Phase 26 (33.3%)

Phase 33 (16.7%)

Phase 43 (16.7%)

N/A2 (11.1%)

Trials by Status

terminated16%

withdrawn317%

active_not_recruiting16%

completed844%

unknown317%

not_yet_recruiting211%

Recent Activity

1 active trials

Showing 5 of 18

not_yet_recruitingphase_1

Vasodilator Therapy With Isosorbide Mononitrate or Diltiazem to Reduce Vasotoxicity in Patients With Gastrointestinal Cancer Receiving Fluoropyrimidine Therapy

NCT07456852

not_yet_recruitingphase_3

Isosorbide Mononitrate and Butylphthalide to Reduce the Risk of Disability in Patients With Acute Lacunar Stroke (IMPACT)

NCT07252544

active_not_recruitingnot_applicable

Cervical Ripening With Misoprostol vs Isosorbide Mononitrate ; A Parallel -Arm Randomized Controlled Trial

NCT07121634

completedphase_4

Nitric Oxide Donor Isosorbide Mono Nitrate for Cervical Ripening in Induction of Labor

NCT03544606

withdrawnphase_2

Termination Of Anembryonic Pregnancy

NCT02573051

View all 18 trials

Clinical Trials (18)

Showing 18 of 18 trials

NCT07456852Phase 1

Vasodilator Therapy With Isosorbide Mononitrate or Diltiazem to Reduce Vasotoxicity in Patients With Gastrointestinal Cancer Receiving Fluoropyrimidine Therapy

Not Yet Recruiting

NCT07252544Phase 3

Isosorbide Mononitrate and Butylphthalide to Reduce the Risk of Disability in Patients With Acute Lacunar Stroke (IMPACT)

Not Yet Recruiting

NCT07121634Not Applicable

Cervical Ripening With Misoprostol vs Isosorbide Mononitrate ; A Parallel -Arm Randomized Controlled Trial

Active Not Recruiting

NCT03544606Phase 4

Nitric Oxide Donor Isosorbide Mono Nitrate for Cervical Ripening in Induction of Labor

Completed

NCT02573051Phase 2

Termination Of Anembryonic Pregnancy

Withdrawn

NCT04051957Phase 2

Isosorbide Mononitrate For Anti-Vascular Endothelial Growth Factor (VEGF) Induced Kidney Injury

Terminated

NCT05341856Early Phase 1

Uterine Artery Doppler Changes After Vaginal Administration of Isosorbide Mononitrate In Patients With URPL

Unknown

NCT04729088Phase 1

Pharmacokinetics Trial of Isosorbide Mononitrate 0.5% Gel for Intra Anal Application in Healthy Subjects

Withdrawn

NCT04312048Phase 3

the Effect of Isosorbide Mononitrate in Reducing Pain During Cooper Intrauterine Device Insertion

Completed

NCT03665779Phase 3

Nitric Oxide Donor Isosorbide Mono Nitrate for Induction of Labor With Pre-labor Rupture of Membranes

Completed

NCT03854383Phase 2

Using Isosorbide Mononitrate in Reducing Time in Induction of Labor in Post Date Women

Unknown

NCT03587077Not Applicable

Pain Relief During IUD Insertion in Women Delivered Only by Elective Cesarean Section

Unknown

NCT03407521Phase 4

Misoprosotol and Isosorbide Mononitrate for Induction of Second Trimester Abortion

Completed

NCT02481323Phase 2

Lacunar Intervention Trial 1 (LACI-1)

Completed

NCT02667535Phase 1

PK, PD and Safety Comparative Trial of Isosorbide Mononitrate Gel in Healthy Participants and With Anal Fissure

Withdrawn

NCT02053493Phase 2

Nitrate's Effect on Activity Tolerance in Heart Failure With Preserved Ejection Fraction

Completed

NCT02712125Phase 2

Nitric Oxide Donors for Treatment of Isolated Oligohydramnios

Completed

NCT00450164Phase 4

Secondary Prophylaxis After Variceal Bleeding in Non-Responders

Completed

All 18 trials loaded

Drug Details

Intervention Type: DRUG
Total Trials: 18