Success Metrics

Clinical Success Rate
50.0%

Based on 5 completed trials

Completion Rate
50%(5/10)
Active Trials
42(71%)
Results Posted
120%(6 trials)
Terminated
5(8%)

Phase Distribution

Ph early_phase_1
1
2%
Ph phase_2
35
59%
Ph phase_1
15
25%
Ph phase_3
8
14%

Phase Distribution

16

Early Stage

35

Mid Stage

8

Late Stage

Phase Distribution59 total trials
Early Phase 1First-in-human
1(1.7%)
Phase 1Safety & dosage
15(25.4%)
Phase 2Efficacy & side effects
35(59.3%)
Phase 3Large-scale testing
8(13.6%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

41.7%

5 of 12 finished

Non-Completion Rate

58.3%

7 ended early

Currently Active

42

trials recruiting

Total Trials

59

all time

Status Distribution
Active(45)
Completed(5)
Terminated(7)
Other(2)

Detailed Status

Active, not recruiting22
Recruiting20
Terminated5
Completed5
Not yet recruiting3
unknown2

Development Timeline

Analytics

Development Status

Total Trials
59
Active
42
Success Rate
50.0%
Most Advanced
Phase 3

Trials by Phase

Early Phase 11 (1.7%)
Phase 115 (25.4%)
Phase 235 (59.3%)
Phase 38 (13.6%)

Trials by Status

terminated58%
unknown23%
withdrawn23%
completed58%
recruiting2034%
active_not_recruiting2237%
not_yet_recruiting35%

Recent Activity

Clinical Trials (59)

Showing 20 of 59 trialsScroll for more
NCT04126200Phase 1

Platform Study of Belantamab Mafodotin as Monotherapy and in Combination With Anti-cancer Treatments in Participants With Relapsed/Refractory Multiple Myeloma (RRMM)

Active Not Recruiting
NCT04653246Phase 2

Isatuximab, Lenalidomide, Bortezomib, and Dexamethasone in NDMM

Active Not Recruiting
NCT04763616Phase 2

Study of Isatuximab and Cemiplimab in Relapsed or Refractory Natural Killer/T-cell Lymphoid Malignancy

Completed
NCT02960555Phase 2

Isatuximab With or Without Lenalidomide in Patients With High Risk Smoldering Multiple Myeloma (ISAMAR)

Active Not Recruiting
NCT06182774Phase 3

Fixed Duration vs Continuous Anti-CD38 Antibody Therapy Among Transplant Ineligible Older Adults With Newly-Diagnosed Multiple Myeloma

Recruiting
NCT05873205Phase 2

Open-Label, Phase II Trial of Isatuximab for Patients With Refractory Immune Cytopenias After Allogeneic Hematopoietic Cell Transplantation

Active Not Recruiting
NCT04643002Phase 1

Isatuximab in Combination With Novel Agents in RRMM - Master Protocol

Recruiting
NCT07479979Phase 1

Study of Selinexor With Carfilzomib, Isatuximab and Dexamethasone for Patients With Relapsed and/or Refractory Multiple Myeloma

Not Yet Recruiting
NCT05272826Phase 2

Study of Iberdomide, Bortezomib, Dexamethasone With Isatuximab Added on Demand for ND-NTE MM Patients

Recruiting
NCT05690984Phase 2

Elimination of Minimal Residual Disease After Transplant

Active Not Recruiting
NCT04883242Phase 2

Isatuximab, Carfilzomib, Pomalidomide, and Dexamethasone for the Treatment of Relapsed or Refractory Multiple Myeloma

Active Not Recruiting
NCT06203912Phase 1

Donor Immune Cells (TGFbi NK Cells) and Isatuximab for the Treatment of Relapsed or Refractory Multiple Myeloma

Active Not Recruiting
NCT05344833Phase 2

Post-Autologous Transplant Maintenance With Isatuximab and Lenalidomide in Minimal Residual Disease Positive Multiple Myeloma

Recruiting
NCT05804032Phase 3

Lenalidomide, Bortezomib and Dexamethasone Induction Therapy With Either Intravenous or Subcutaneous Isatuximab in Patients With Newly Diagnosed Multiple Myeloma

Completed
NCT04754945Phase 1

Isatuximab as Upfront Therapy for the Treatment of High Risk AL Amyloidosis

Active Not Recruiting
NCT04751877Phase 3

Multicenter Open Label Phase 3 Study of Isatuximab Plus Lenalidomide and Dexamethasone With/Without Bortezomib in the Treatment of Newly Diagnosed Non Frail Transplant Ineligible Multiple Myeloma Elderly Patients (≥ 65; < 80 Years).

Active Not Recruiting
NCT03617731Phase 3

Trial on the Effect of Isatuximab to Lenalidomide/Bortezomib/Dexamethasone (RVd) Induction and Lenalidomide Maintenance in Patients With Newly Diagnosed Myeloma (GMMG HD7)

Active Not Recruiting
NCT06216158Phase 3

Iberdomide vs. Iberdomide Plus Isatuximab Maintenance Therapy Post ASCT in Newly Diagnosed Multiple Myeloma

Recruiting
NCT04430894Phase 2

KRDI in Transplant-Eligible MM

Active Not Recruiting
NCT04240054Phase 2

Bortezomib, Isatuximab, Cyclophosphamide and Dexamethasone Induction in Transplant-Eligible Multiple Myeloma Patients With Renal Insufficiency

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
59