Success Metrics

Clinical Success Rate
74.2%

Based on 276 completed trials

Completion Rate
74%(276/372)
Active Trials
197(31%)
Results Posted
88%(243 trials)
Terminated
96(15%)

Phase Distribution

Ph phase_4
6
1%
Ph early_phase_1
9
1%
Ph phase_3
53
8%
Ph not_applicable
3
0%
Ph phase_1
269
42%
Ph phase_2
285
45%

Phase Distribution

278

Early Stage

285

Mid Stage

59

Late Stage

Phase Distribution625 total trials
Early Phase 1First-in-human
9(1.4%)
Phase 1Safety & dosage
269(43.0%)
Phase 2Efficacy & side effects
285(45.6%)
Phase 3Large-scale testing
53(8.5%)
Phase 4Post-market surveillance
6(1.0%)
N/ANon-phased studies
3(0.5%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

68.7%

276 of 402 finished

Non-Completion Rate

31.3%

126 ended early

Currently Active

197

trials recruiting

Total Trials

637

all time

Status Distribution
Active(205)
Completed(276)
Terminated(126)
Other(30)

Detailed Status

Completed276
Active, not recruiting116
Terminated96
Recruiting81
Withdrawn30
unknown26

Development Timeline

Analytics

Development Status

Total Trials
637
Active
197
Success Rate
74.2%
Most Advanced
Phase 4

Trials by Phase

Early Phase 19 (1.4%)
Phase 1269 (43.0%)
Phase 2285 (45.6%)
Phase 353 (8.5%)
Phase 46 (1.0%)
N/A3 (0.5%)

Trials by Status

not_yet_recruiting81%
recruiting8113%
withdrawn305%
completed27643%
active_not_recruiting11618%
unknown264%
suspended41%
terminated9615%

Recent Activity

Clinical Trials (637)

Showing 20 of 637 trialsScroll for more
NCT03866382Phase 2

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

Recruiting
NCT07532902Phase 1

A Study of BMS-986504 With Standard-of-Care Therapy for People With Solid Tumor Cancer

Recruiting
NCT06049576Phase 1

Nivolumab and Ipilimumab With and Without Camu Camu for the Treatment of Patients With Metastatic Renal Cell Carcinoma

Active Not Recruiting
NCT05112601Phase 2

Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma

Recruiting
NCT06946797Phase 2

A Study to Evaluate Two Dosing Regimens of Subcutaneous Nivolumab in Combination With Intravenous Ipilimumab and Chemotherapy in Participants With Previously Untreated Metastatic or Recurrent Non-Small Cell Lung Cancer (NSCLC)

Recruiting
NCT03776487Phase 2

Nivolumab, Ipilimumab and Chemoradiation in Treating Patients With Resectable Gastric Cancer

Active Not Recruiting
NCT07291076Phase 1

A Study to Evaluate the Safety and Tolerability of Pumitamig Alone or In Combination With Ipilimumab in Participants With First-Line Advanced or Unresectable Hepatocellular Carcinoma (HCC) (ROSETTA HCC-206)

Recruiting
NCT03017820Phase 1

A Vaccine (VSV-hIFNβ-NIS) With or Without Cyclophosphamide and Combinations of Ipilimumab, Nivolumab, and Cemiplimab in Treating Relapsed or Refractory Multiple Myeloma, Acute Myeloid Leukemia or Lymphoma

Recruiting
NCT04929041Phase 2

Testing the Addition of Radiation Therapy to the Usual Treatment (Immunotherapy With or Without Chemotherapy) for Advanced Stage Non-small Cell Lung Cancer Patients Who Are PD-L1 Negative

Suspended
NCT02496208Phase 1

Cabozantinib S-malate and Nivolumab With or Without Ipilimumab in Treating Patients With Metastatic Genitourinary Tumors

Active Not Recruiting
NCT02834013Phase 2

Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

Active Not Recruiting
NCT04840589Phase 1

Testing the Combination of ZEN003694 and Nivolumab With or Without Ipilimumab in Solid Tumors

Suspended
NCT04317105Phase 1

Testing the Addition of an Anti-cancer Drug, Copanlisib, to the Usual Immunotherapy (Nivolumab With or Without Ipilimumab) in Patients With Advanced Solid Cancers That Have Changes in the Following Genes: PIK3CA and PTEN

Active Not Recruiting
NCT03793166Phase 3

Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer, The PDIGREE Study

Active Not Recruiting
NCT02453620Phase 1

Entinostat, Nivolumab, and Ipilimumab in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery or Locally Advanced or Metastatic HER2-Negative Breast Cancer

Active Not Recruiting
NCT06743126Phase 3

SUPRAME-ACTengine® IMA203 vs. Investigator's Choice of Treatment in Previously Treated, Unresectable or Metastatic Cutaneous Melanoma

Recruiting
NCT04751370Phase 2

Testing Nivolumab and Ipilimumab With Short-Course Radiation in Locally Advanced Rectal Cancer

Active Not Recruiting
NCT05407441Phase 1

Tazemetostat+Nivo/Ipi in INI1-Neg/SMARCA4-Def Tumors

Active Not Recruiting
NCT05896839Phase 1

Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metastatic Skin Cancer

Recruiting
NCT03604991Phase 2

Nivolumab and Ipilimumab in Treating Patients With Esophageal and Gastroesophageal Junction Adenocarcinoma Undergoing Surgery

Suspended

Drug Details

Intervention Type
BIOLOGICAL
Total Trials
637