Success Metrics

Clinical Success Rate
73.8%

Based on 284 completed trials

Completion Rate
74%(284/385)
Active Trials
191(30%)
Results Posted
87%(248 trials)
Terminated
101(16%)

Phase Distribution

Ph early_phase_1
9
1%
Ph phase_3
53
8%
Ph phase_2
286
45%
Ph phase_4
6
1%
Ph not_applicable
3
0%
Ph phase_1
269
42%

Phase Distribution

278

Early Stage

286

Mid Stage

59

Late Stage

Phase Distribution626 total trials
Early Phase 1First-in-human
9(1.4%)
Phase 1Safety & dosage
269(43.0%)
Phase 2Efficacy & side effects
286(45.7%)
Phase 3Large-scale testing
53(8.5%)
Phase 4Post-market surveillance
6(1.0%)
N/ANon-phased studies
3(0.5%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

68.4%

284 of 415 finished

Non-Completion Rate

31.6%

131 ended early

Currently Active

191

trials recruiting

Total Trials

638

all time

Status Distribution
Active(194)
Completed(284)
Terminated(131)
Other(29)

Detailed Status

Completed284
Active, not recruiting115
Terminated101
Recruiting76
Withdrawn30
unknown24

Development Timeline

Analytics

Development Status

Total Trials
638
Active
191
Success Rate
73.8%
Most Advanced
Phase 4

Trials by Phase

Early Phase 19 (1.4%)
Phase 1269 (43.0%)
Phase 2286 (45.7%)
Phase 353 (8.5%)
Phase 46 (1.0%)
N/A3 (0.5%)

Trials by Status

active_not_recruiting11518%
recruiting7612%
unknown244%
terminated10116%
withdrawn305%
completed28445%
suspended51%
not_yet_recruiting30%

Recent Activity

Clinical Trials (638)

Showing 20 of 638 trialsScroll for more
NCT05896839Phase 1

Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metastatic Skin Cancer

Recruiting
NCT03604978Phase 1

Nivolumab and Multi-fraction Stereotactic Radiosurgery With or Without Ipilimumab in Treating Patients With Recurrent Grade II-III Meningioma

Active Not Recruiting
NCT01134614Phase 2

Ipilimumab With or Without Sargramostim in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery

Active Not Recruiting
NCT03866382Phase 2

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

Recruiting
NCT04079712Phase 2

Testing the Combination of XL184 (Cabozantinib), Nivolumab, and Ipilimumab for Poorly Differentiated Neuroendocrine Tumors

Active Not Recruiting
NCT02314169Phase 2

Nivolumab With or Without Ipilimumab in Treating Patients With Refractory Metastatic Anal Canal Cancer

Active Not Recruiting
NCT04145115Phase 2

A Study Testing the Effect of Immunotherapy (Ipilimumab and Nivolumab) in Patients With Recurrent Glioma With Elevated Mutational Burden

Active Not Recruiting
NCT01274338Phase 3

Ipilimumab or High-Dose Interferon Alfa-2b in Treating Patients With High-Risk Stage III-IV Melanoma That Has Been Removed by Surgery

Active Not Recruiting
NCT06866262Phase 1

Inulin Gel in Combination With Ipilimumab and Nivolumab for the Treatment of Metastatic or Locally Advanced Kidney Cell Cancer, ICON Trial

Recruiting
NCT02453620Phase 1

Entinostat, Nivolumab, and Ipilimumab in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery or Locally Advanced or Metastatic HER2-Negative Breast Cancer

Active Not Recruiting
NCT03816332Phase 1

Tacrolimus, Nivolumab, and Ipilimumab in Treating Kidney Transplant Recipients With Selected Unresectable or Metastatic Cancers

Active Not Recruiting
NCT02339571Phase 2

A Phase II/III Trial of Nivolumab, Ipilimumab, and GM-CSF in Patients With Advanced Melanoma

Active Not Recruiting
NCT03914300Phase 2

Testing the Combination of Cabozantinib, Nivolumab, and Ipilimumab (CaboNivoIpi) for Advanced Differentiated Thyroid Cancer

Active Not Recruiting
NCT04840589Phase 1

Testing the Combination of ZEN003694 and Nivolumab With or Without Ipilimumab in Solid Tumors

Suspended
NCT02224781Phase 3

Dabrafenib and Trametinib Followed by Ipilimumab and Nivolumab or Ipilimumab and Nivolumab Followed by Dabrafenib and Trametinib in Treating Patients With Stage III-IV BRAFV600 Melanoma

Active Not Recruiting
NCT05112601Phase 2

Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma

Recruiting
NCT03604991Phase 2

Nivolumab and Ipilimumab in Treating Patients With Esophageal and Gastroesophageal Junction Adenocarcinoma Undergoing Surgery

Suspended
NCT03816345Phase 1

Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

Recruiting
NCT02506153Phase 3

Physician/Patient Choice of Either High-Dose Recombinant Interferon Alfa-2B or Ipilimumab, Versus Pembrolizumab in Treating Patients With Stage III-IV High Risk Melanoma That Has Been Removed by Surgery

Active Not Recruiting
NCT04290546Phase 1

CIML NK Cell in Head & Neck Cancer

Completed

Drug Details

Intervention Type
DRUG
Total Trials
638